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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
Australian Journal of Chemistry

Australian Journal of Chemistry

Volume 74 Number 9 2021

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The alignment of intended learning outcomes for chemistry graduates and the actualised outcomes has been called into question recently. This article provides an overview of three literature-based chemistry education approaches to address this: authentic research experiences, engaging students in citizen science projects, and curriculum reform aligned with systems thinking frameworks.

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Enantiomerically enriched or homochiral cis-1,2-dihydrocatechols such as 10 have been elaborated via their Diels–Alder adducts (e.g. 20) and then the corresponding sulfites (e.g. 21 and 22) into the title compounds 23.

CH21137Tandem Oxidation-Dehydrogenation of (Hetero)Arylated Primary Alcohols via Perruthenate Catalysis

Christian J. Bettencourt 0000-0001-5855-9198, Sharon Chow 0000-0001-8193-3504, Peter W. Moore 0000-0003-0527-4249, Christopher D. G. Read 0000-0002-1967-7287, Yanxiao Jiao 0000-0003-2678-4723, Jan Peter Bakker, Sheng Zhao, Paul V. Bernhardt 0000-0001-6839-1763 and Craig M. Williams 0000-0002-3834-7398
pp. 652-659
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A novel method is described, using perruthenate salts, for performing the rarely reported dehydrogenation of primary alcohols to afford unsaturated aldehydes in low to moderate yields. The discovery, method development, reaction scope, and associated challenges of this method are presented in detail.

CH21122Theoretical Determination of pKas of P(1)-H Phospholes and their Comparison with N(1)-H Azoles

Sanjeev Rachuru 0000-0002-6117-7112, Jagannadham Vandanapu 0000-0001-9152-7729 and Adam A. Skelton 0000-0003-0155-8287
pp. 660-668
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In this article, the pKas of seven phospholes were determined theoretically. The major challenge in their determination is that the experimental pKas of all the seven phospholes are not reported in the literature. We are the first ones to endeavour to calculate their pKas.

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We developed a simple and selective fluorescent aptasensor for the detection of oxytetracycline (OTC) using aptamer-conjugated gold nanoparticles (AuNPs) and a complex formed between oxytetracycline and a europium cation. In this study, AuNPs were modified with an OTC aptamer using two methods (Tween and NaCl methods).

CH21156Synthesis of Three Dimensional Cs-γ-CD-MOFs and the Adsorption of Myricetin

Lan Xie, Yangyang Zheng, Jie Deng, Wenkang Jiang and Huijun Liu 0000-0002-7126-4738
pp. 676-683
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A new Cs-γ-CD-MOF material was synthesised by an improved gas vapour diffusion method. The adsorption capacity of γ-CD (142.92 mg g−1) and Cs-γ-CD-MOFs (280.05 mg g−1) for myricetin was compared. The energy and conformation of the adsorption of myricetin on Cs-γ-CD-MOFs were obtained by molecular docking.

CH21120Temperature Replica Exchange Molecular Dynamics Simulations of Cyclic Peptide Conformation

Karen M. Corbett 0000-0002-7430-9188, Colin W. Pouton and David K. Chalmers
pp. 684-685
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Cyclic peptides have pharmaceutical, materials chemistry, and agricultural applications. Structure–function relationships are essential to understanding cyclic peptide activity and developing novel, functional cyclic peptides. Computer simulations, in particular temperature replica exchange molecular dynamics simulations (TREMDS), allow in-depth study of cyclic peptide conformations. Here, we discuss the background of TREMDS and their recent applications to the study of cyclic peptide conformations.

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