Charms & Harms: Ginkgo

Abstract

SUMMARY MESSAGE: Evidence for the efficacy of ginkgo extracts for cognitive impairment and dementia, intermittent claudication, acute ischaemic stroke, tinnitus and age-related macular degeneration is unconvincing. Ginkgo preparations have been associated with haemorrhagic reactions. Health professionals should be aware of the possibility of (undisclosed) use of ginkgo; use of ginkgo should be avoided, or at least used only with caution, in patients with bleeding disorders and those taking conventional anti-platelet or anticoagulant agents. If using ginkgo, these patients should be advised to be vigilant for signs of bleeding and to seek professional help. Suspected adverse drug reactions should be reported to CARM. As with all herbal medicines, different ginkgo products vary in their pharmaceutical quality, and the implications of this for efficacy and safety should be considered.