Treatment of diseases using nucleic acid-based approaches is of increasing importance. However, these drugs need to be delivered in nanoparticles to ensure high bioavailability. To ensure the formation of well-defined nanoparticles, flow assembly is increasingly employed. In this review, we map the pathways to nucleic acid-loaded polymer-based nanoparticles prepared by flow.

In intramolecular reactions of benzene derivatives with alkenes, meta or [2 + 3] photocycloadditions take place in competition with ortho or [2 + 2] additions and complex structures are obtained. The substitution pattern and the spin multiplicity significantly affect the competition between the two reaction modes. A topological analysis facilitates the application these photoreactions to target oriented synthesis.

This review article highlights the state of the art in solid-state SEC (ultraviolet–visible–near-infrared (UV-Vis-NIR), infrared (IR), Raman, photoluminescence, electron paramagnetic resonance (EPR), and X-ray absorption (XAS) spectroscopy) relevant to interrogating solid-state materials, particularly those in the burgeoning field of metal–organic frameworks (MOFs).