Register      Login
Journal of Primary Health Care Journal of Primary Health Care Society
Journal of The Royal New Zealand College of General Practitioners
RESEARCH ARTICLE (Open Access)

Milk thistle

Rayna Sharma 1 , E Lyn Lee 2 , Jo Barnes https://orcid.org/0000-0002-1522-8433 1 *
+ Author Affiliations
- Author Affiliations

1 School of Pharmacy, University of Auckland, Auckland, PB 92019, New Zealand.

2 Kuala Lumpur, Malaysia.

* Correspondence to: j.barnes@auckland.ac.nz

Journal of Primary Health Care 16(3) 319-321 https://doi.org/10.1071/HC24131
Submitted: 29 August 2024  Accepted: 2 September 2024  Published: 9 September 2024

© 2024 The Author(s) (or their employer(s)). Published by CSIRO Publishing on behalf of The Royal New Zealand College of General Practitioners. This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND)

Key references

Marmouzi I, Bouyahya A, Ezzat SM, et al. The food plant Silybum marianum (L.) Gaertn.: phytochemistry, ethnopharmacology and clinical evidence. J Ethnopharmacol 2021; 265: 113303.
| Crossref | Google Scholar | PubMed |

Bokelmann JM. Medicinal herbs in primary care. Philadelphia: Elsevier; 2021. Chapter 61, Milk Thistle (Silybum marianum): Seeds, Flower Heads. Available at https://www.sciencedirect.com/book/9780323846769/medicinal-herbs-in-primary-care [cited 6 March 2024].

Yang Z, Zhuang L, Lu Y, et al. Effects and tolerance of silymarin (milk thistle) in chronic hepatitis C virus infection patients: a meta-analysis of randomized controlled trials. Biomed Res Int 2014; 2014: 941085 PMCID: PMC4163440.
| Crossref | Google Scholar | PubMed |

Mayer KE, Myers RP, Lee SS. Silymarin treatment of viral hepatitis: a systematic review. J Viral Hepat 2005; 12(6): 559-67.
| Crossref | Google Scholar | PubMed |

Zhong S, Fan Y, Yan Q, et al. The therapeutic effect of silymarin in the treatment of nonalcoholic fatty disease: a meta-analysis (PRISMA) of randomized control trials. Medicine 2017; 96(49): e9061 PMCID: PMC5728929.
| Crossref | Google Scholar | PubMed |

Rambaldi A, Jacobs BP, Gluud C. Milk thistle for alcoholic and/or hepatitis B or C virus liver diseases. Cochrane Database Syst Rev 2007; 2007(4): CD003620.
| Crossref | Google Scholar | PubMed |

Stockley’s Herbal Medicines Interactions. Pharmaceutical Press. Available at https://about.medicinescomplete.com/publication/stockleys-herbal-medicines-interactions-2/ [cited 27 August 2024].

Xie Y, Zhang D, Zhang J, et al. Metabolism, transport and drug-drug interactions of silymarin. Molecules 2019; 24(20): 3693 PMCID: PMC6832356.
| Crossref | Google Scholar | PubMed |