Improved prospects for food allergy prevention
Rohan Ameratunga1 Auckland City Hospital, Grafton, Auckland, New Zealand
Correspondence to: Rohan Ameratunga, Auckland City Hospital, Park Rd, Grafton 1010, Auckland, New Zealand. Email: rohana@adhb.govt.nz
Journal of Primary Health Care 9(4) 254-257 https://doi.org/10.1071/HC17042
Published: 13 October 2017
Journal Compilation © Royal New Zealand College of General Practitioners 2017.
This is an open access article licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Abstract
Three recent publications from Professor Gideon Lack have fundamentally changed our understanding of how to prevent food allergy. His team has shown that early introduction of allergenic foods may prevent food allergy in most but not all high-risk children. Various allergy and paediatric societies around the world are changing their recommendations based on these three studies. It appears there is a window of opportunity to safely introduce allergenic foods to high-risk children. This has resource implications, as some of these children will need testing and food challenges.
KEY POINT: Allergenic foods must be introduced as soon as safely possible to at-risk children.
References
[1] Crooks C, Ameratunga R, Simmons G, et al. The changing epidemiology of food allergy–implications for New Zealand. N Z Med J. 2008; 121 74–82.[2] Osborne NJ, Koplin JJ, Martin PE, et al. Prevalence of challenge-proven IgE-mediated food allergy using population-based sampling and predetermined challenge criteria in infants. J Allergy Clin Immunol. 2011; 127 668–76.e2.
| Prevalence of challenge-proven IgE-mediated food allergy using population-based sampling and predetermined challenge criteria in infants.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3MXjs1Wlu78%3D&md5=2a286fca2adf93e7519e53c3686b10b9CAS |
[3] Crooks C, Ameratunga R, Brewerton M, et al. Adverse reactions to food in New Zealand children aged 0–5 years. N Z Med J. 2010; 123 14–23.
[4] Du Toit G, Roberts G, Sayre PH, et al. Randomized trial of peanut consumption in infants at risk for peanut allergy. N Engl J Med. 2015; 372 803–13.
| Randomized trial of peanut consumption in infants at risk for peanut allergy.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC2MXjvFGnsLo%3D&md5=bab233accfa2cf042547a3eb441d888cCAS |
[5] Du Toit G, Sayre PH, Roberts G, et al. Effect of avoidance on peanut allergy after early peanut consumption. N Engl J Med. 2016; 374 1435–43.
| Effect of avoidance on peanut allergy after early peanut consumption.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC28Xht1Ojtb%2FJ&md5=257607665421c1c422ec9d09c4fb240cCAS |
[6] Perkin MR, Logan K, Tseng A, et al. Randomized trial of introduction of allergenic foods in breast-fed infants. N Engl J Med. 2016; 374 1733–43.
| Randomized trial of introduction of allergenic foods in breast-fed infants.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC28XhtlOltLnO&md5=3ad0220273db65eb0a1e6dd14327c193CAS |
[7] du Toit G, Tsakok T, Lack S, Lack G. Prevention of food allergy. J Allergy Clin Immunol. 2016; 137 998–1010.
| Prevention of food allergy.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC28XlsF2nu7k%3D&md5=6b733e51b5f16d4920e85bb1113c2d42CAS |
[8] Du Toit G, Katz Y, Sasieni P, et al. Early consumption of peanuts in infancy is associated with a low prevalence of peanut allergy. J Allergy Clin Immunol. 2008; 122 984–91.
| Early consumption of peanuts in infancy is associated with a low prevalence of peanut allergy.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXhtlGgsr3L&md5=6ccf6362bf46fa98ce6b228f8cee58adCAS |
[9] Togias A, Cooper SF, Acebal ML, et al. Addendum guidelines for the prevention of peanut allergy in the United States: report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel. J Allergy Clin Immunol. 2017; 139 29–44.
| Addendum guidelines for the prevention of peanut allergy in the United States: report of the National Institute of Allergy and Infectious Diseases-sponsored expert panel.Crossref | GoogleScholarGoogle Scholar |