Controlled ion and molecule transfer, the basis for many natural processes, is starting to be harnessed in a range of rudimentary supramolecular systems using a range of stimuli. An overview of biocompatible and purely artificial molecule-based systems employing intra- and intermolecular transfer processes is presented.

The use of lanthanide ion-directed synthesis in the formation of supramolecular self-assembly structures is described, focussing on recent examples from the literature.

Selenium-induced cyclization of 4-hydroxy-5-pentenylamines and 5-hydroxy-6-hexenylamines occurs with regio- and stereo-selectivity. Substituted pyrrolidines and piperidines are then afforded by oxidation of the Se^II intermediate to Se^VI and subsequent substitution with nucleophiles.

Three new morphine-based compounds containing arginyl and tetra-arginyl substitutents have been prepared. All had relatively high affinity for opoid receptors and the tetraarginyl compound showed some promise as an analgesic. None of the molecules showed transdermal activity.

Three new coordination compounds of Co^II/Cu^II with 5-nitro-1,2,3-benzenetricarboxylate (O₂N-btcH₃) and 4,4′-bipyridyl ligands were synthesized and crystallographically characterized. It is found that these complexes are constructed by bi-/tri-nuclear secondary building units (SBUs) and exhibit intriguing 2D or 3D topological networks.

Synchrotron data for the yellow polymorph of PtCl₂(bipy) and PdI₂(bipy) allow determination of crystal structures, and a comparison of structural chemistry for the series MX₂(bipy) (M = Pd, Pt; X = Cl, Br, I) with nine structures distributed over five space groups.

Typical POCl₃ contains predominantly ¹⁶O; consequently the reaction of POCl₃ with water that is highly enriched in ¹⁸O produces predominantly five ^16,18O isotope analogues of H₃PO₄. The proportions of the corresponding ^16,18O isotope analogues of [H₂PO₄]^–, estimated by electrospray ionization mass spectrometry, show that the O from POCl₃ and H₂O mix randomly into H₃PO₄.

A new series of studies was carried out for 2-chloro-2,2-difluoroacetamide (CDFA) in order to complete its characterization. Following this goal, thermal decomposition, vapour FT-IR, mass spectrometry, low-temperature NMR, and theoretical studies were performed. Also, conformational analysis was carried out both experimentally and theoretically for CDFA in protic and aprotic solvents.

A series of 2D and 3D novel lanthanide complexes constructed from squarate C₄O₄^2– are prepared. Three new coordination modes, a bidentate/monodentate μ3 and two bidentate/monodentate μ4 coordination modes, are first reported. In addition, the variable-temperature magnetic properties, the solid-state near-infrared (NIR) luminescence spectra, and the thermogravimetric analyses are discussed.

CuX-oxidant systems are studied for the preparation of 5-halo-1,4-disubstituted-1,2,3-triazoles by the combination of a CuAAC reaction and an oxidative halogenation reaction in one pot, and an efficient method for the preparation of these kind of compounds under mild conditions is developed.

A series of novel homocamptothecin derivatives conjugating with dihydropyridine derivates were designed and synthesized based on a semisynthetic route. Most of the synthesized compounds exhibited good cytotoxic activity on tumour cell lines and showed superior Topo I inhibition activity comparable to or higher than camptothecins.

Aliphatic nitrile oxides were generated in situ, by dehydration of terminal nitro compounds, and reacted with dipolarophiles using continuous flow techniques to afford substituted isoxazolines. In-line scavenger cartridges conveniently removed by-products and unreacted reagents to give almost pure crude products.

Constructive embedding is developed so that one can elaborate new polyenes that have known embeddability.

Porphyrin-fullerene tetrad with Langmuir­­–Blodget films on Au substrates shows diode-like behaviour. Photocurrent polarity can be switched from cathodic to anodic and vice versa by changing the subtrate potential. Photoelectrochemical properties of this system were used to mimic a two-channel demultiplexer.