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Reproduction, Fertility and Development Reproduction, Fertility and Development Society
Vertebrate reproductive science and technology
Reproduction, Fertility and Development

Reproduction, Fertility and Development

Volume 37 Number 5 2025

RD24164Maternal aging reduces female fecundity and alters offspring phenotype in a sex-specific manner

Macarena B. Gonzalez 0000-0002-6567-938X, Eryk Andreas, Yasmyn E. Winstanley 0000-0002-0196-0965, Haley S. Connaughton, Karagh E. Loring, Cheryl Shoubridge 0000-0002-0157-3084 and Rebecca L. Robker 0000-0002-1538-4604

Diagram summarising the effects of maternal aging on fecundity and offspring phenotype.

More couples are delaying childbearing, which unfortunately can negatively influence the health of their child. Using reproductively old mice at 12 months old, we examined the characteristics of the offspring of older mothers at birth, and then followed them to adulthood and measured markers of adult health, namely growth, glucose tolerance, immune function and behaviour. This study provides insights into how maternal age influences the health and development of their offspring. Image by Macarena B. Gonzalez.

This article belongs to the collection: Frontiers in Reproduction Science – Rising Stars at the Society for Reproductive Biology 2023.

RD24127Sodium alginate and bovine serum albumin co-combined improved the cryopreservation quality of boar sperm through the PI3K-AKT pathway

Jing Wang, Yongyong Rao, Chongfan Du, Ao Wang, Yanling Wu, Ruiyi Lin, Tianfang Xiao and Weimin Lin 0000-0001-7348-4614

Schematic diagram showing how SA and BSA together improve the quality of cryopreserved sperm.

The optimization of sperm freezing and storage program has an important impact on reducing breeding costs, improving reproductive efficiency, overcoming reproductive diseases, and protecting germplasm resources. In this paper, we have included two potential additives, sodium alginate (SA) and bovine serum albumin (BSA), which can effectively improve sperm motility after cryopreservation. This is of great significance for improving the quality of pig semen, improving reproductive ability and the development of modern pig breeding industry. Image by Jing Wang using Figdraw.

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