The relevance of probiotics in Caesarean-born neonates
Hanna E Sidjabat A E , Alaa Mohammed Ali Alsaggaf B , Akshatha Gopalakrishna B , Evelyn Nadar B , Adam Irwin B C and Pieter Koorts D
+ Author Affiliations
- Author Affiliations
A Menzies Health Institute Queensland, Griffith University, Gold Coast, Qld 4222, Australia
B The University of Queensland, UQ Centre for Clinical Research, Herston, Qld 4029, Australia
C Infection Management and Prevention Service, Children’s Health Queensland Hospital and Health Service, Brisbane, Qld 4101, Australia
D Grantley Stable Neonatal Unit and Queensland Milk Bank, Royal Brisbane and Women’s Hospital, Brisbane, Qld 4029, Australia
E Email: h.sidjabat@griffith.edu.au
Microbiology Australia 41(2) 75-81 https://doi.org/10.1071/MA20020
Published: 27 May 2020
Abstract
There is growing interest in the use of probiotics in neonates. In particular, Lactobacillus rhamnosus, L. acidophilus, Bifidobacterium breve and B. longum have been well studied. Caesarean-section (CS)-born infants often lack Lactobacillus spp. and Bifidobacterium spp., which showed increasing evidence in establishing the neonatal immune system. Furthermore, CS increases the difficulties for mothers in initiating and sustaining breastfeeding. Increasing evidence shows CS-born infants are more susceptible to allergy, infections and chronic inflammatory diseases later in life. The number of CS births has increased continuously, now accounting for 35% of all deliveries Australia wide. In this context, probiotics may have a role in establishing a healthy neonatal gut microbiome.
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