Congenital and perinatal cytomegalovirus (CMV): has diagnosis improved in 30 years?

Abstract

The implication of a diagnosis of cytomegalovirus (CMV) during pregnancy or in the neonatal period remains uncertain despite our increased understanding of the pathophysiology of the disease. Current tests for CMV include serological tests (usually EIA IgG, IgM, avidity) and nucleic acid testing (NAT). When used together, these tests offer improved reliability in diagnosis of CMV in pregnant women and infants.