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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

Facile Preparation of Highly Luminescent Nitrogen-Doped Carbonaceous Nanospheres and Potential Application in Intracellular Imaging of Quercetin

Buhong Gao A , Yu Sun B , Yingchun Miao A , Huihua Min A , Li Xu B D and Chaobo Huang C D
+ Author Affiliations
- Author Affiliations

A Advanced Analysis and Testing Center, Nanjing Forestry University, Nanjing 210037, China.

B College of Science, Nanjing Forestry University, Nanjing 210037, China.

C College of Chemical Engineering, Nanjing Forestry University, Nanjing 210037, China.

D Corresponding authors. Email: xuliby@njfu.edu.cn; 1377655972@qq.com

Australian Journal of Chemistry 71(11) 882-889 https://doi.org/10.1071/CH18370
Submitted: 3 August 2018  Accepted: 13 September 2018   Published: 10 October 2018

Abstract

Highly luminescent nitrogen-doped carbonaceous nanospheres (LNCNs) were synthesized by a one-pot hydrothermal reaction of β-cyclodextrin (β-CD) and branched polyethylenimine (BPEI). Both the N-doping and amino-functionalisation of LNCNs were achieved simultaneously. The prepared LNCNs display excellent properties such as high physical and chemical stability, excitation wavelength-independent emission, and high photoluminescence quantum yields. Importantly, the LNCNs exhibit a quenching of photoluminescence in the presence of quercetin (Qc) based on the simple static quenching mechanism, making it possible to quantify concentrations from 0.5 to 80 μg mL−1 with a detection limit of 0.21 μg mL−1. Furthermore, the LNCNs probe was further used for imaging Qc in living cells.


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