Detection of candidate genes for growth and carcass traits using genome-wide association strategy in Chinese Simmental beef cattle
Wengang Zhang A , Lingyang Xu A , Huijiang Gao A , Yang Wu A B , Xue Gao A , Lupei Zhang A , Bo Zhu A , Yuxin Song A , Jinshan Bao C , Junya Li A D and Yan Chen A D
+ Author Affiliations
- Author Affiliations
A Institute of Animal Science, Chinese Academy of Agricultural Science, No. 2 Yuanmingyuan West Road, Haidian District, Beijing 100193, China.
B Queensland Brain Institute, The University of Queensland, Brisbane, Qld 4072, Australia.
C Veterinary Bureau of Wulagai Precinct in Xilin Gol League, Wulagai 026321, China.
D Corresponding author. Email: JL1@iascaas.net.cn; chenyan0204@163.com
Animal Production Science 58(2) 224-233 https://doi.org/10.1071/AN16165
Submitted: 17 March 2016 Accepted: 17 August 2016 Published: 9 November 2016
Abstract
In Chinese beef cattle industry, there are more than 60 million livestock, nearly half of which are Chinese Simmental beef cattle or Simmental crossbreds. Over the past decades, numerous quantitative trait loci for economic traits in cattle have been identified, while few studies for growth and carcass traits have been reported in Simmental beef cattle. In the present study, we conducted genome-wide association study based on BovineHD BeadChip and identified 41, 15, 3, 22 and 16 single-nucleotide polymorphisms significantly associated with average daily gain, liveweight before slaughter, carcass weight, dressing percentage and pure meat percentage respectively. In total, 18 candidate genes were found for growth and carcass traits, and four haplotype blocks for growth and carcass traits were discovered. These findings will facilitate detection of major genes and genetic variants involved in growth and carcass traits of beef cattle in further studies.
Additional keywords: Average Daily Gain, Dressing Percentage, Genome-wide Association Study, Quantitative Trait Loci.
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