Dapoxetine has been approved for treatment of premature ejaculation for more than 10 years, but the efficacy and safety of dapoxetine in clinical practice remains unclear. This study found that dapoxetine can achieve a moderate extension on ejaculation time, however more practice in the real world is needed. This review can guide clinical practice and help patients to receive safe and efficacious medication scientifically from a physiological and psychological perspective.

Despite high rates of HIV and other sexually transmissible infections, men who have sex with men (MSM) in low- and middle-income countries face numerous barriers in accessing sexual health services. This review examines key elements to improving MSM sexual health services, focusing on creation of safe and confidential clinic environments, implementing innovative approaches to healthcare delivery, such as using mobile technology, self-testing, and crowdsourcing interventions.

Patient-delivered partner therapy (PDPT) for chlamydia is an effective and safe additional partner management strategy, but guidance around its implementation is lacking in Australia. We developed and evaluated a pilot program of PDPT in publicly funded sexual health services and Family Planning NSW clinics. Our pilot demonstrated the successful implementation of a PDPT model for chlamydia in heterosexual patients, providing guidance on its use as standard of care and highlighting the need for PDPT to be implemented in general practice, where most chlamydia is diagnosed.

Recruitment for trials is challenging and can limit the success of trial outcomes. The aim of this study was to look at what helped and hindered the recruitment efforts of clinics, doctors and people with HIV (PWHIV) to the HealthMap trial. Developing and maintaining relationships between researchers and clinicians will ensure that research is clinically relevant and enhance recruitment.

Female sex workers (FSWs) in Burkina Faso are regularly exposed to violence and risks of psychological and physical trauma. The objective was to understand the experiences of violence and mental health symptomatology. Using mixed-methods, 696 FSWs were recruited via respondent-driven sampling. Respondents reported high levels of violence after initiating sex work. Nearly half of quantitative participants (41.8%) reported ever having feelings of depression. There was also a high prevalence of suicide ideation among both quantitative and qualitative participants.

Many individuals living with chronic hepatitis B do not know they are infected and are not engaged in care. The 2016 Victorian Hepatitis B Strategy includes targets to increase diagnostic testing. We used data from the ACCESS surveillance system to describe hepatitis B testing and positivity in Victoria, Australia. Collection of hepatitis B diagnostic testing data provides an important mechanism to monitor progress towards implementation of the 2016 Victorian Hepatitis B Strategy.

Access to medical transition and gender-affirming health care may facilitate access to HIV care among transgender (trans) women living with HIV (WLWH). Drawing on quantitative data from 48 trans WLWH and qualitative data from a sub-sample of 11 participants, this convergent parallel mixed methods study shows that HIV-related stigma and social determinants of health limit access to medical transition for trans WLWH. Stigma must be addressed in a broad range of healthcare settings, in addition to structural barriers, to increase access to gender-affirming HIV care and medical transition for trans WLWH.

In Chile, partner notification is an unexplored strategy for syphilis cases. Perspectives from healthcare providers who work in public health services revealed that Internet partner notification could be a feasible strategy, but they were concerned about confidentiality, privacy and efficacy, given the local cultural context. As the attitudes of Chilean patients about Internet partner notification is currently unknown, further research is needed.

People who inject drugs are a priority for HIV prevention. This survey demonstrated a small proportion of this population would be eligible for HIV pre-exposure prophylaxis in Australia. However, given the size of the population, this may still equate to several thousand individuals nationally.

The aging process and a decrease in testosterone levels increase the odds of men experiencing sexual difficulties. Sexual difficulties were associated with lower relational and sexual satisfaction, whereas instrumental masculinity was associated with higher relational and sexual satisfaction of middle-aged and older men. Health providers should consider the relational dimension when developing interventions to reduce sexual difficulties, namely sexual dysfunction.

The 7.5-kbp chlamydial cryptic plasmid is an important molecular target for the detection of Chlamydia trachomatis. Using molecular assays targeting various regions of the chlamydial cryptic plasmid and other stable chromosomal targets, we identified a plasmid-deficient chlamydial strain in Queensland, Australia. The presence of a plasmid-deficient C. trachomatis strain serves as a timely reminder that the use of multitarget assays is superior for the successful detection of C. trachomatis.