This article introduces and summarizes the contents of this special edition. Given the exceptional potential of condoms to avert epidemics of sexually transmitted infections and teen or unintended pregnancy – even in low-resource environments – this in-depth examination of current knowledge, practice, and issues with condoms and their use is an important asset for educators and practitioners worldwide.

Despite a global epidemic of sexually transmissible infections and the availability and endorsement of condoms as an effective intervention, the overall use of condoms remains low. This review explores various challenges and opportunities to fully realizing the prevention potential for condoms.

The authors reviewed data on the effectiveness and acceptability of the female condom for protection against pregnancy and sexually transmissible infections (STIs), including HIV. The data available suggest that female condoms (or a mixture of female and male condoms) may provide similar degrees of protection against pregnancy and STIs as do latex male condoms alone; however, this conclusion has not been demonstrated and thus comparative research is urgently needed..

In this article we review condom use in China, with a focus on the populations that are at high risk for HIV/sexually transmissible infection. We also review policies related to condom promotion and the challenges facing this endeavour and tend to provide recommendations to promoting condom use in China.

This review article summarizes findings of sexual behavior research studies recently carried out in central and eastern Europe. This world region has seen one of the most rapidly increasing HIV epidemics, which coincided with fundamental political, economic, and social transformations. Studies of injection drug users, commercial sex workers, men who have sex with men, adolescents and young adults all reported inconsistent condom use. Risk behavior patterns are discussed, and public health recommendations are being suggested.

Condom social marketing interventions deliver risk reduction messages and about one-quarter of all condoms used worldwide. The primary challenge today is for social marketing agencies and their stakeholders, public and commercial sector supply sources, to collaborate to achieve universal coverage of condoms among the vulnerable while increasing cost-effectiveness and equity..

In South Africa male condoms are available widely in the public, social marketing and the private sectors. The female condom program is well-established. Increasing condom use rates at last sex are reported; however, inconsistent and incorrect use are major challenges impeding the condom program’s success. This article reviews current condom guidelines, policies, distribution and uptake. We discuss the main challenges to condom use, including both user and service-related issues.

The use of condoms in conjunction with other contraceptive methods has substantial benefits for both pregnancy prevention and STI prevention, but rates of dual method use in the USA are comparatively low. This article reviews the literature on trends and covariates of dual method use in the USA, identifying those factors most strongly associated with dual method use and identifying key areas for future research and interventions.

Condom migration, the common practice of couples abandoning condom use after adopting a similar protective behavior, continues to undermine innovations in HIV preventions. This article reviews studies investigating migration from one contraceptive method to another contraceptive and studies investigating migration from one disease prevention method to another. The results provide an updated review of condom migration as a means of highlighting methodological issues for future studies of this behavioural issue.

Although historically, sexuality-related issues have received little systematic attention in the field of public health, researchers are now paying more attention to the role of pleasure and sexual arousal in condom use. In this commentary, it is argued that a better integration of findings from the area of sex research into the HIV and sexually transmissible infection (STI) field is needed to develop and improve programs to reduce the risk of STIs and unintended pregnancy.