Social-ecological factors associated with trajectories of adolescent sexual and reproductive health stigma: longitudinal cohort findings with urban refugee youth in Kampala
Carmen H. Logie A B C D * , Moses Okumu E F , Frannie MacKenzie A , Daniel Kibuuka-Musoke G , Robert Hakiza H , Brenda Katisi H , Aidah Nakitende G , Lawrence Mbuagbaw I J K L M N , Peter Kyambadde O P and Zerihun Admassu AA
B
C
D
E
F
G
H
I
J
K
L
M
N
O
P
Abstract
Stigma towards sexually active young people presents profound barriers to uptake of sexual and reproductive health (SRH) services, including HIV testing and contraception. Yet, few studies have examined adolescent SRH stigma trajectories over time. To address this knowledge gap, we examined associations between social-ecological factors and trajectories of adolescent SRH stigma among urban refugee youth in Kampala, Uganda.
This longitudinal cohort study with refugee youth in Kampala collected data on adolescent SRH stigma at four time-points between 2022 and 2024. We used latent class growth analyses to examine distinct trajectories of adolescent SRH stigma, and examined baseline social-ecological and socio-demographic factors associated with class membership using multivariable logistic regression.
Among the participants (n = 164 with n = 668 observations; mean age 19.9 years, standard deviation 2.5 years; 52.8% cisgender women), we categorised two distinct adolescent SRH stigma trajectories: consistently high (n = 496; 74.2%) and sustained low (n = 172; 25.8%). In multivariable analyses, living in Uganda ≥1 year at baseline assessment (1–5 years: adjusted odds ratio [aOR] 5.28, confidence interval [CI] 2.29–12.19, P < 0.001; 6–10 years: aOR 6.20, CI 2.61–14.69, P < 0.001; or >10 years: aOR 3.89, CI 1.56–9.68, P < 0.01) compared with <1 year, unemployment (aOR 1.62, CI 1.02–2.56, P < 0.05), having children (aOR 2.84, CI 1.30–6.21, P < 0.05), past 3-month multiple sexual partners (aOR 6.14, CI 1.73–21.75, P < 0.01) and higher depression symptoms (aOR 1.04, CI 1.01–1.08, P < 0.01) were associated with the consistently high (vs sustained low) adolescent SRH stigma trajectory.
Social-ecological and socio-demographic factors were associated with consistently high levels of adolescent SRH stigma over 2 years. Multi-level strategies can meaningfully engage youth in developing stigma reduction strategies for SRH service delivery.
Keywords: adolescents, adolescent parents, depression, longitudinal, multiple sex partners, refugee, sexual and reproductive health, social-ecological theory, stigma, stigma drivers, Uganda.
References
1 Logie CH, Okumu M, Mwima SP, et al. Exploring associations between adolescent sexual and reproductive health stigma and HIV testing awareness and uptake among urban refugee and displaced youth in Kampala, Uganda. Sex Reprod Health Matters 2019; 27: 86-106.
| Crossref | Google Scholar | PubMed |
2 Hall KS, Manu A, Morhe E, et al. Development and validation of a scale to measure adolescent sexual and reproductive health stigma: results from young women in Ghana. J Sex Res 2018; 55: 60-72.
| Crossref | Google Scholar | PubMed |
3 Hall KS, Morhe E, Manu A, et al. Factors associated with sexual and reproductive health stigma among adolescent girls in Ghana. PLoS ONE 2018; 13: e0195163.
| Crossref | Google Scholar | PubMed |
4 Stangl AL, Earnshaw VA, Logie CH, et al. The health stigma and discrimination framework: a global, crosscutting framework to inform research, intervention development, and policy on health-related stigmas. BMC Med 2019; 17: 31.
| Crossref | Google Scholar | PubMed |
5 Berger MT. Workable Sisterhood: The political journey of stigmatized women with HIV/AIDS. Perspect Polit 2005; 3(4): 869-70.
| Crossref | Google Scholar |
6 Sievwright KM, Stangl AL, Nyblade L, et al. An expanded definition of intersectional stigma for public health research and praxis. Am J Public Health 2022; 112: S356-S361.
| Crossref | Google Scholar |
7 Stangl AL, Atkins K, Leddy AM, et al. What do we know about interventions to reduce intersectional stigma and discrimination in the context of HIV? A systematic review. Stigma Health 2023; 8: 393-408.
| Crossref | Google Scholar |
8 Nyblade L, Stockton M, Nyato D, et al. Perceived, anticipated and experienced stigma: exploring manifestations and implications for young people’s sexual and reproductive health and access to care in North-Western Tanzania. Cult Health Sex 2017; 19: 1092-1107.
| Crossref | Google Scholar | PubMed |
9 Jennings L, George AS, Jacobs T, et al. A forgotten group during humanitarian crises: a systematic review of sexual and reproductive health interventions for young people including adolescents in humanitarian settings. Confl Health 2019; 13: 57.
| Crossref | Google Scholar |
10 McCann TV, Mugavin J, Renzaho A, et al. Sub-Saharan African migrant youths’ help-seeking barriers and facilitators for mental health and substance use problems: a qualitative study. BMC Psychiatry 2016; 16: 275.
| Crossref | Google Scholar | PubMed |
11 Logie CH, Okumu M, Musoke DK, et al. Intersecting stigma and HIV testing practices among urban refugee adolescents and youth in Kampala, Uganda: qualitative findings. J Int AIDS Soc 2021; 24(3): e25674.
| Crossref | Google Scholar |
12 Frounfelker RL, Miconi D, Farrar J, et al. Mental health of refugee children and youth: epidemiology, interventions and future directions. Annu Rev Public Health 2020; 41: 159-176.
| Crossref | Google Scholar | PubMed |
13 Logie CH. Mobile health-supported HIV self-testing strategy among urban refugee and displaced youth in Kampala, Uganda: protocol for a cluster randomized trial (Tushirikiane, Supporting Each Other). JMIR Res Protoc 2021; 10(2): e26192.
| Crossref | Google Scholar |
14 Logie CH, Okumu M, Kortenaar J-L, et al. Mobile health–supported virtual reality and group problem management plus: protocol for a cluster randomized trial among urban refugee and displaced youth in Kampala, Uganda (Tushirikiane4MH, Supporting Each Other for Mental Health). JMIR Res Protoc 2022; 11: e42342.
| Crossref | Google Scholar | PubMed |
15 Logie CH, Okumu M, Berry I, et al. Kukaa Salama (Staying Safe): Study protocol for a pre/post-trial of an interactive mHealth intervention for increasing COVID-19 prevention practices with urban refugee youth in Kampala, Uganda. BMJ Open 11: e055530.
| Crossref | Google Scholar |
16 Kroenke K, Spitzer RL. The PHQ-9: a new depression diagnostic and severity measure. Psychiatr Ann 2002; 32: 509-515.
| Crossref | Google Scholar |
17 van der Nest G, Lima Passos V, Candel MJJM, et al. An overview of mixture modelling for latent evolutions in longitudinal data: modelling approaches, fit statistics and software. Adv Life Course Res 2020; 43: 100323.
| Crossref | Google Scholar | PubMed |
18 Herle M, Micali N, Abdulkadir M, et al. Identifying typical trajectories in longitudinal data: modelling strategies and interpretations. Eur J Epidemiol 2020; 35: 205-222.
| Crossref | Google Scholar | PubMed |
19 Naldi L, Cazzaniga S. Research techniques made simple: latent class analysis. J Invest Dermatol 2020; 140: 1676-1680.e1.
| Crossref | Google Scholar |
20 Weaver LJ, Mendenhall E. Applying syndemics and chronicity: interpretations from studies of poverty, depression, and diabetes. Med Anthropol 2014; 33: 92-108.
| Crossref | Google Scholar |
21 Malama K, Logie CH, Okumu M, et al. Factors associated with motherhood among urban refugee adolescent girls and young women in informal settlements in Kampala, Uganda. Women Health 2023; 63: 51-58.
| Crossref | Google Scholar | PubMed |
22 Steventon Roberts K, Smith C, Toska E, et al. Risk factors for poor mental health among adolescent mothers in South Africa. Psychol Health Med 2022; 27: 67-84.
| Crossref | Google Scholar | PubMed |
23 Logie CH, Marcus N, Wang Y, et al. A longitudinal study of associations between HIV-related stigma, recent violence and depression among women living with HIV in a Canadian cohort study. J Int AIDS Soc 2019; 22: e25341.
| Crossref | Google Scholar |
24 Wardell JD, Shuper PA, Rourke SB, et al. Stigma, coping, and alcohol use severity among people living with HIV: a prospective analysis of bidirectional and mediated associations. Ann Behav Med 2018; 52: 762-772.
| Crossref | Google Scholar | PubMed |
25 Logie CH, Okumu M, Berry I, et al. Findings from the Tushirikiane mobile health (mHealth) HIV self-testing pragmatic trial with refugee adolescents and youth living in informal settlements in Kampala, Uganda. J Int AIDS Soc 2023; 26: e26185.
| Crossref | Google Scholar | PubMed |
26 Logie CH, MacKenzie F, Malama K, et al. Sexual and reproductive health among forcibly displaced persons in urban environments in low and middle-income countries: scoping review findings. Reprod Health 2024; 21: 51.
| Crossref | Google Scholar |
27 Elshahat S, Moffat T, Newbold KB. Understanding the healthy immigrant effect in the context of mental health challenges: a systematic critical review. J Immigrant Minority Health 2022; 24: 1564-79.
| Crossref | Google Scholar | PubMed |
28 Miller KE, Rasmussen A. The mental health of civilians displaced by armed conflict: an ecological model of refugee distress. Epidemiol Psychiatr Sci 2017; 26: 129-138.
| Crossref | Google Scholar | PubMed |
29 Riley A, Varner A, Ventevogel P, et al. Daily stressors, trauma exposure, and mental health among stateless Rohingya refugees in Bangladesh. Transcult Psychiatry 2017; 54: 304-331.
| Crossref | Google Scholar | PubMed |
30 Logie CH, Okumu M, Admassu Z, et al. Applying the index of vulnerability approach to understand water insecurity and other social-ecological factors associated with depression among urban refugee youth in Kampala, Uganda. SSM - Mental Health 2024; 5: 100306.
| Crossref | Google Scholar |
31 Silove D, Ventevogel P, Rees S. The contemporary refugee crisis: an overview of mental health challenges. World Psychiatry 2017; 16: 130-139.
| Google Scholar |
32 Logie CH, Shannon K, Braschel M, et al. Brief report: social factors associated with trajectories of HIV-related stigma and everyday discrimination among women living with HIV in Vancouver, Canada: longitudinal cohort findings. J Acquir Immune Defic Syndr 2023; 94: 190-195.
| Crossref | Google Scholar | PubMed |
33 Logie CH, Sokolovic N, Kazemi M, et al. Does resource insecurity drive HIV-related stigma? Associations between food and housing insecurity with HIV-related stigma in cohort of women living with HIV in Canada. J Int AIDS Soc 2022; 25: e25913.
| Crossref | Google Scholar | PubMed |
34 Leddy AM, Turan JM, Johnson MO, et al. Poverty stigma is associated with suboptimal HIV care and treatment outcomes among women living with HIV in the US. AIDS 2019; 33: 1379-1384.
| Crossref | Google Scholar |
35 Norcini Pala A, Kempf M-C, Konkle-Parker D, et al. Intersectional stigmas are associated with lower viral suppression rates and antiretroviral therapy adherence among women living with HIV. AIDS 2022; 36: 1769-1776.
| Crossref | Google Scholar | PubMed |
36 Hansen H, Bourgois P, Drucker E. Pathologizing poverty: new forms of diagnosis, disability, and structural stigma under welfare reform. Soc Sci Med 2014; 103: 76-83.
| Crossref | Google Scholar | PubMed |
37 Michaels E, Thomas M, Reeves A, et al. Coding the everyday discrimination scale: implications for exposure assessment and associations with hypertension and depression among a cross section of mid-life African American women. J Epidemiol Community Health 2019; 73: 577-584.
| Crossref | Google Scholar |
38 Nyblade L, Stockton MA, Giger K, et al. Stigma in health facilities: why it matters and how we can change it. BMC Med 2019; 17: 25.
| Crossref | Google Scholar | PubMed |
39 Nyblade L, Stangl A, Weiss E, et al. Combating HIV stigma in health care settings: what works? J Int AIDS Soc 2009; 12: 15.
| Crossref | Google Scholar |
40 Logie CH, Okumu M, Loutet M, et al. A participatory comic book workshop to improve youth-friendly post-rape care in a Humanitarian Context in Uganda: a case study. Glob Health Sci Pract 2023; 11(3): e2200088.
| Crossref | Google Scholar |
41 James S, Pisa PT, Imrie J, et al. Assessment of adolescent and youth friendly services in primary healthcare facilities in two provinces in South Africa. BMC Health Serv Res 2018; 18: 809.
| Crossref | Google Scholar | PubMed |
42 Chidwick H, Baumann A, Ogba P, et al. Exploring adolescent engagement in sexual and reproductive health research in Kenya, Rwanda, Tanzania, and Uganda: a scoping review. PLOS Glob Public Health 2022; 2: e0000208.
| Crossref | Google Scholar | PubMed |
43 Mannell J, Willan S, Shahmanesh M, et al. Why interventions to prevent intimate partner violence and HIV have failed young women in southern Africa. J Int AIDS Soc 2019; 22: e25380.
| Crossref | Google Scholar |