Register      Login
Sexual Health Sexual Health Society
Publishing on sexual health from the widest perspective
RESEARCH ARTICLE (Open Access)

The chlamydia care cascade of young people attending Australian general practices; a descriptive study to assess gaps in care

J. Jung https://orcid.org/0000-0003-1041-9588 A B * , R. Biezen A , J. L. Goller https://orcid.org/0000-0001-5580-360X C , J. Hocking https://orcid.org/0000-0001-9329-8501 C , P. Chondros A and J. Manski-Nankervis A
+ Author Affiliations
- Author Affiliations

A Department of General Practice, Melbourne Medical School, University of Melbourne, Carlton, Vic., Australia.

B Melbourne Sexual Health Centre, Alfred Health, Melbourne, Vic., Australia.

C Melbourne School of Population and Global Health, University of Melbourne, Carlton, Vic., Australia.

* Correspondence to: changjune.jung@unimelb.edu.au

Handling Editor: Weiming Tang

Sexual Health - https://doi.org/10.1071/SH23096
Submitted: 23 May 2023  Accepted: 13 September 2023   Published online: 2 October 2023

© 2023 The Author(s) (or their employer(s)). Published by CSIRO Publishing. This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND)

Abstract

Background

Most chlamydia infections in Australia are diagnosed in general practice. The care cascade concept (testing, treatment and re-testing) can be utilised to explore the management of chlamydia infections. We explored the chlamydia care cascade among young people attending general practices in Australia.

Methods

We analysed de-identified electronic medical record data for 16–29-year-old individuals attending 70 Australian general practices between January 2018 and December 2020. Five outcomes: (1) chlamydia testing, (2) positivity, (3) treatment, (4) re-testing and (5) re-infection were summarised as annual counts and proportions per calendar year. Logistic regression was used to investigate the association of age, gender and clinic location with each outcome.

Results

During the study period, a total of 220 909 clinical episodes involving 137 358 16–29-year-olds were recorded. Of these episodes, 10.45% (n = 23 077, 95% CI 8.73–12.46) involved a chlamydia test. Of 1632 chlamydia cases, 88.79% (n = 1449, 95% CI 86.37–90.82) had appropriate antibiotics recorded as defined in Australian sexually transmitted infection management guidelines. Of 183 chlamydia cases that did not have appropriate antibiotics recorded, 46.45% (n = 85) had re-attended the clinic within 90 days of diagnosis. Among 1068 chlamydia cases that had appropriate antibiotic recorded in 2018 and 2019, 22.57% (n = 241, 95% CI 20.15–25.18) were re-tested within 6 weeks to 4 months of their diagnosis. One-third of episodes of chlamydia cases that did not have a re-test recorded (n = 281) had re-attended the clinics within 4 months of diagnosis.

Conclusion

Our study provides insight into chlamydia management by analysing general practice medical records, indicating substantial gaps in testing and re-testing for 16–29-year-olds. These data can also be used to explore the impact of future interventions to optimise chlamydia management.

Keywords: care cascade, chlamydia, electronic health record, epidemiology, general practice, primary care, routinely collected clinic data, sexually transmissible infection.

References

Kirby Institute. HIV, viral hepatitis and sexually transmissible infections in Australia: annual surveillance report 2021. Sydney: Kirby Institute, UNSW Sydney; 2021. p. 9–16.

Australasian Society for HIV, Viral Hepatitis and Sexual Health Medicine (ASHM). Australian STI management guidelines for use in primary care. 2021. Available at http://www.sti.guidelines.org.au/sexually-transmissible-infections/chlamydia [accessed May 2022]

Gaydos CA. Chlamydia trochomaris. In: Goldman MB, Troisi R, Rextode KM, editors. Women and health. 2nd edn. San Diego, United States: Elsevier Science & Technology; 2013. pp. 445–59.

Goller JL, De Livera AM, Guy RJ, et al. Rates of pelvic inflammatory disease and ectopic pregnancy in Australia, 2009–2014: ecological analysis of hospital data. Sex Transm Infect 2018; 94(7): 534-41.
| Crossref | Google Scholar |

Subbaraman R, Nathavitharana RR, Mayer KH, et al. Constructing care cascades for active tuberculosis: a strategy for program monitoring and identifying gaps in quality of care. PLoS Med 2019; 16(2): e1002754.
| Crossref | Google Scholar | PubMed |

Gray RT, Callander D, Hocking JS, et al. Population-level diagnosis and care cascade for chlamydia in Australia. Sex Transm Infect 2020; 96(2): 131-6.
| Crossref | Google Scholar | PubMed |

The Royal Australian College of General Practitioners. Guidelines for preventive activities in general practice. 9th edn, updated. East Melbourne: RACGP; 2018. pp. 61–5.

Richey CM, Macaluso M, Hook EW, III. Determinants of reinfection with Chlamydia trachomatis. Sex Transm Dis 1999; 26(1): 4-11.
| Crossref | Google Scholar | PubMed |

Lang AS, An der Heiden M, Jansen K, et al. Not again! Effect of previous test results, age group and reason for testing on (re-)infection with Chlamydia trachomatis in Germany. BMC Infect Dis 2018; 18(1): 424.
| Crossref | Google Scholar | PubMed |

10  Gaydose CA, Crotchfelt KA, Howell MR, et al. Molecular amplification assays to detect chlamydial infections in urine specimens from high school female students and to monitor the persistence of chlamydial DNA after therapy. J Infect Dis 1998; 177(2): 417-24.
| Crossref | Google Scholar |

11  Grulich AE, de Visser RO, Smith AMA, Risse CE, Richters J. Sex in Australia: sexually transmissible infection and blood-borne virus history in a representative sample of adults. Aust N Z J Public Health 2003; 27(2): 234-41.
| Crossref | Google Scholar |

12  Australian Institute of Family Studies, Australian Government. Age of consent laws in Australia; 2021. Available at https://aifs.gov.au/resources/resource-sheets/age-consent-laws-australia [accessed August 2023]

13  Australian Bureau of Statistics. Patient experiences in Australia: summary of findings. Canberra: ABS; 2019-20. Available at https://www.abs.gov.au/statistics/health/health-services/patient-experiences/2019-20 [accessed July 2023]

14  Gordon J, Britt H, Miller GC, et al. General practice statistics in Australia: pushing a round peg into a square hole. Int J Environ Res Public Health 2022; 19: 1912.
| Crossref | Google Scholar | PubMed |

15  Eastern Melbourne Primary Health Network. EMPHN needs assessment report; 2018. p. 36. Available at https://www.emphn.org.au/images/uploads/files/EMPHN-Needs-Assessment_Final-DoH-2018-2021.pdf [accessed July 2023]

16  Gippsland Primary Health Network. Gippsland PHN health needs assessment; 2021. p. 21. Available at https://gphn.org.au/wp-content/uploads/2022/04/Gippsland-PHN-Health-Needs-Assessment-November-2021-APPROVED-website-version.pdf [accessed July 2023]

17  Murray Primary Health Network. Population health needs assessment 2018-2022; 2018. p. 21. Available at https://www.murrayphn.org.au/wp-content/uploads/2019/02/Murray-PHN-Needs-Assessment.pdf [accessed July 2023]

18  North Western Melbourne Melbourne Primary Health Network. Health need assessement 2022 to 2025, p. 1. 2021. Available at https://nwmphn.org.au/wp-content/uploads/2022/06/NWMPHN-Health-Needs-Assessment-Summary_Public-Release.pdf [accessed July 2023]

19  South Eastern Melbourne Primary Health Network. Annual need assessment 2022-2025; 2022. p. 10. Available at https://irp.cdn-website.com/b60ea18f/files/uploaded/SEMPHN_2022%20Health%20Needs%20Assessment%20Upd.pdf [accessed July 2023]

20  Western Victoria Primary Health Network. WVPHN needs assessment; 2021. p. 7. Available at https://westvicphn.com.au/wp-content/uploads/2022/04/2021-WVPHN-Needs-Assessment-FINAL-Public.pdf [accessed July 2023]

21  The University of Melbourne. Data for decisions and the patron program of research. 2023. Available at https://medicine.unimelb.edu.au/school-structure/general-practice/engagement/data-for-decisions [accessed May 2022]

22  Therapeutic Guidelines. Approach to chlamydia trachomatis infection. 2022. Available at https://www.tg.org.au/ [accessed May 2022], subscription required.

23  Australian Government, Department of Health and Aged Care. Modified monash model 2021. 2023. Available at https://www.health.gov.au/health-topics/rural-health-workforce/classifications/mmm [accessed May 2022]

24  StataCorp. Stata statistical software: release 15. College Station, TX: StataCorp; 2017.

25  Adams G, Gulliford MC, Ukoumunne OC, et al. Patterns of intra-cluster correlation from primary care research to inform study design and analysis. J Clin Epidemiol 2004; 57(8): 785-94.
| Crossref | Google Scholar | PubMed |

26  Hocking JS, Parker RM, Pavlin N, et al. What needs to change to increase chlamydia screening in general practice in Australia? The views of general practitioners. BMC Public Health 2008; 8: 425.
| Crossref | Google Scholar | PubMed |

27  Chow EPF, Hocking JS, Ong JJ, et al. Sexually transmitted infection diagnoses and access to a sexual health service before and after the national lockdown for COVID-19 in Melbourne, Australia. Open Forum Infect Dis 2021; 8(1): offa536.
| Crossref | Google Scholar |

28  Bowring AL, Gouillou M, Guy R, et al. Missed opportunities-low levels of chlamydia retesting at Australian general practices, 2008-2009. Sex Transm Infect 2012; 88(5): 330-4.
| Crossref | Google Scholar |

29  Davies B, Ward H, Leung S, et al. Heterogeneity in risk of pelvic inflammatory diseases after chlamydia infection: a population-based study in Manitoba, Canada. J Infect Dis 2014; 210(Suppl 2): S549-S5.
| Crossref | Google Scholar |

30  Statista. Percentage of primary care physicians in selected countries using electronic medical records (EMR) as of 2019. 2023. Available at https://www.statista.com/statistics/236985/use-of-electronic-medical-records/ [accessed May 2022]

31  Canaway R, Boyle DI, Manski-Nankervis J-AE, et al. Gathering data for decisions: best practice use of primary care electronic records for research. Med J Aust 2019; 210(6): S12-6.
| Crossref | Google Scholar |

32  Walker J, Fairley CK, Walker SM, et al. Computer reminders for chlamydia screening in general practice: a randomized controlled trial. Sex Transm Dis 2010; 37(7): 445-50.
| Crossref | Google Scholar | PubMed |

33  Bissessor M, Fairley CK, Leslie D, et al. Use of a computer alert increases detection of early, asymptomatic syphilis among higher-risk men who have sex with men. Clin Infect Dis 2011; 53(1): 57-8.
| Crossref | Google Scholar | PubMed |

34  Deeks A, Lombard C, Michelmore J, Teede H. The effects of gender and age on health related behaviors. BMC Public Health 2009; 9: 213.
| Crossref | Google Scholar | PubMed |