Sociodemographic characteristics and clinical description of congenital syphilis patients and their mothers in Japan: a qualitative study, 2016
Mizue Kanai A B , Yuzo Arima C G , Tomoe Shimada C , Narumi Hori D , Takuya Yamagishi C , Tomimasa Sunagawa C , Yuki Tada E , Takuri Takahashi C , Makoto Ohnishi F , Tamano Matsui C and Kazunori Oishi CA Field Epidemiology Training Program, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
B Division of Global Infectious Diseases, Department of Infection and Epidemiology, Graduate School of Medicine, Tohoku University, Sendai 980-8575, Japan.
C Infectious Disease Surveillance Center, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
D Disease Control and Prevention Center, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku-ku, Tokyo 162-8655, Japan.
E Travellers’ Medical Center, Tokyo Medical University Hospital, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.
F Department of Bacteriology I, National Institute of Infectious Diseases, 1-23-1 Toyama, Shinjuku-ku, Tokyo 162-8640, Japan.
G Corresponding author. Email: arima@niid.go.jp
Sexual Health 15(5) 460-467 https://doi.org/10.1071/SH18033
Submitted: 2 March 2018 Accepted: 27 June 2018 Published: 21 September 2018
Journal Compilation © CSIRO 2018 Open Access CC BY-NC-ND
Abstract
Background: In Japan, congenital syphilis (CS) notifications have increased recently. However, little is known about the CS cases or the clinical and sociodemographic characteristics of the patients’ mothers. Methods: Twelve cases of CS were reported through national surveillance in the period March–December 2016, and the mothers of seven patients were included in this study. The patients’ mothers and physicians completed a self-administered questionnaire, providing sociodemographic and clinical information of the patients and their mothers. In addition, we explored the awareness and knowledge of, attitudes towards and practices regarding CS occurrence through semistructured interviews with the mothers. Results: Of the seven CS patients, three were asymptomatic, with a range of non-specific clinical manifestations in the rest. The mothers tended to be of young age, unmarried and to have a history of commercial sex work, other sexually transmissible infections (STIs) and no or irregular prenatal care visits during pregnancy. Of the four mothers who had had regular prenatal care visits, two had tested negative for syphilis at the first trimester antenatal screening. Themes emerged that indicated challenges in preventing CS, including a lack of guidance or guidelines for physicians to consider testing for syphilis after the first trimester, lack of physicians’ awareness or experience of syphilis or CS and a lack of awareness or knowledge in pregnant women regarding STIs. Conclusions: Key characteristics of recent CS patients and their mothers in Japan were revealed, identifying previously reported factors as well as new challenges. A holistic approach, designed to address challenges at the level of the healthcare system, healthcare provider and the pregnant woman and her partner will be important in preventing CS.
Additional keywords: Asia, social context, surveillance.
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