Impact of HIV-1 infection on the clinical presentation of syphilis in men who have sex with men
Craig Tipple
+ Author Affiliations
- Author Affiliations
A Department of Medicine, Imperial College London, St Mary’s Hospital, Norfolk Place, London, W2 1PG, UK. Email: c.tipple@imperial.ac.uk
B Jefferiss Wing Centre for Sexual Health, St Mary’s Hospital, Praed Street, London, W2 1NY, UK.
Sexual Health 12(2) 110-118 https://doi.org/10.1071/SH14157
Submitted: 16 August 2014 Accepted: 13 October 2014 Published: 17 December 2014
Abstract
Men who have sex with men (MSM), especially those with HIV-1 infection, are disproportionately affected by syphilis in higher income countries. The course, and some of the clinical features of the disease, especially the development of neurosyphilis, can be affected by HIV-1 co-infection. This review documents potential differences in the clinical features of syphilis in HIV-1 infected and uninfected MSM and highlights the importance of a thorough examination and high index of suspicion when seeing and treating MSM at risk of sexually transmissible infections.
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