Cloning in companion animal, non-domestic and endangered species: can the technology become a practical reality?
Gabriela F. Mastromonaco A and W. Allan King A B
+ Author Affiliations
- Author Affiliations
A Department of Biomedical Sciences, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada.
B Corresponding author. Email: waking@uoguelph.ca
Reproduction, Fertility and Development 19(6) 748-761 https://doi.org/10.1071/RD07034
Submitted: 26 February 2007 Accepted: 27 April 2007 Published: 2 August 2007
Abstract
Somatic cell nuclear transfer (SCNT) can provide a unique alternative for the preservation of valuable individuals, breeds and species. However, with the exception of a handful of domestic animal species, successful production of healthy cloned offspring has been challenging. Progress in species that have little commercial or research interest, including many companion animal, non-domestic and endangered species (CANDES), has lagged behind. In this review, we discuss the current and future status of SCNT in CANDES and the problems that must be overcome to improve pre- and post-implantation embryo survival in order for this technology to be considered a viable tool for assisted reproduction in these species.
Acknowledgements
The authors would like to thank the funding agencies, Natural Sciences and Engineering Council of Canada, Canada Research Chair Program, and Ontario Graduate Scholarships, for their support of the research in the laboratory of W. A. King.
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