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Telomeres and reproductive aging

David L. Keefe A C and Lin Liu A B
+ Author Affiliations
- Author Affiliations

A Department of Ob/Gyn, University of South Florida, Tampa, FL 33606, USA.

B College of Life Sciences, Nankai University, Tianjin 300071, China.

C Corresponding author. Email: dkeefe@hsc.usf.edu

Reproduction, Fertility and Development 21(1) 10-14 https://doi.org/10.1071/RD08229
Published: 9 December 2008



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Keefe David L.
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Molecular Human Reproduction. 2014 20(1). p.15
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Aviv Abraham
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Mhatre Siddhita D., Iyer Janani, Puukila Stephanie, Paul Amber M., Tahimic Candice G.T., Rubinstein Linda, Lowe Moniece, Alwood Joshua S., Sowa Marianne B., Bhattacharya Sharmila, Globus Ruth K., Ronca April E.
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Science Translational Medicine. 2013 5(172).
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Systems Biology in Reproductive Medicine. 2018 64(6). p.518
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Philosophical Transactions of the Royal Society B: Biological Sciences. 2018 373(1741). p.20170210
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Obstetrical & Gynecological Survey. 2021 76(7). p.429
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REPRODUCTION. 2014 147(5). p.649
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Annual Review of Ecology, Evolution, and Systematics. 2016 47(1). p.25
Telomere lengths in human pronuclei, oocytes and spermatozoa
Turner S., Hartshorne G. M.
Molecular Human Reproduction. 2013 19(8). p.510
Epigenetics and Human Reproduction (2011)
Oliva Rafael, de Mateo Sara
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Rocca Maria Santa, Foresta Carlo, Ferlin Alberto
Biology of Reproduction. 2018
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Steller Jon G., Alberts Jeffrey R., Ronca April E.
International Journal of Molecular Sciences. 2018 19(12). p.3729
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Keefe David L.
European Journal of Medical Genetics. 2020 63(2). p.103638
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Albertini David F.
Journal of Assisted Reproduction and Genetics. 2017 34(7). p.829
Genetic Damage in Human Spermatozoa (2014)
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Reproductive BioMedicine Online. 2016 33(6). p.668
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Current Opinion in Obstetrics & Gynecology. 2017 29(4). p.189
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de Abechuco E. Lopez, Hartmann N., Soto M., Díez G.
Gene Reports. 2016 5 p.117
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Reig-Viader R., Brieno-Enriquez M. A., Khouriauli L., Toran N., Cabero L., Giulotto E., Garcia-Caldes M., Ruiz-Herrera A.
Human Reproduction. 2013 28(2). p.414
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Conn's Handbook of Models for Human Aging (2018)
Duncan Francesca E., Confino Rafael, Pavone Mary Ellen
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Luderer Ulrike
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Stindl Reinhard
Molecular Cytogenetics. 2019 12(1).
Telomeres, Reproductive Aging, and Genomic Instability During Early Development
Keefe David L.
Reproductive Sciences. 2016 23(12). p.1612
Gene expression profiles of single human mature oocytes in relation to age
Grøndahl M.L., Yding Andersen C., Bogstad J., Nielsen F.C., Meinertz H., Borup R.
Human Reproduction. 2010 25(4). p.957
Short telomeres impede germ cell specification by upregulating MAPK and TGFβ signaling
Tian Chenglei, Heng Dai, Zhao Nannan, Liu Linlin, Sheng Xiaoyan, Chen Jiyu, Liu Lin
Science China Life Sciences. 2023 66(2). p.324
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Fertility and Sterility. 2013 99(1). p.23
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Heng Dai, Sheng Xiaoyan, Tian Chenglei, Li Jie, Liu Linlin, Gou Mo, Liu Lin
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Song Chao, Peng Wei, Yin Songna, Zhao Jiamin, Fu Beibei, Zhang Jingcheng, Mao Tingchao, Wu Haibo, Zhang Yong
Scientific Reports. 2016 6(1).
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Alexopoulou Evaggelia, Pinborg Anja, Budtz-Jørgensen Esben, Zedeler Anne
Reproductive Biology. 2019 19(2). p.127
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Bernstein Lori R., Mackenzie Amelia C. L., Lee Se-Jin, Chaffin Charles L., Merchenthaler István
Endocrinology. 2016 157(3). p.1234
Sub-fertile sperm cells exemplify telomere dysfunction
Biron-Shental Tal, Wiser Amir, Hershko-Klement Anat, Markovitch Ofer, Amiel Aliza, Berkovitch Arie
Journal of Assisted Reproduction and Genetics. 2018 35(1). p.143
Telomere lengths in women with early reproductive losses
Huleyuk N. I., Zastavna D. V., Tyrka M.
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Chieffi Baccari Gabriella, Iurato Giuseppe, Santillo Alessandra, Dale Brian
Biomolecules. 2023 13(5). p.745
Optimal doses of EGF and GDNF act as biological response modifiers to improve porcine oocyte maturation and quality
Valleh Mehdi Vafaye, Zandi Nahid Karimi, Rasmussen Mikkel Aabech, Hyttel Poul
Zygote. 2017 25(4). p.423
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Zhang Man, Bener Muhammed Burak, Jiang Zongliang, Wang Tianren, Esencan Ecem, Scott Richard, Horvath Tamas, Seli Emre
Aging. 2019 11(12). p.3919
Molecular basis of reproductive senescence: insights from model organisms
Quesada-Candela Cristina, Loose Julia, Ghazi Arjumand, Yanowitz Judith L.
Journal of Assisted Reproduction and Genetics. 2021 38(1). p.17
Shorter telomere length of white blood cells is associated with higher rates of aneuploidy among infertile women undergoing in vitro fertilization
Hanson Brent M., Tao Xin, Zhan Yiping, Kim Julia G., Klimczak Amber M., Herlihy Nola S., Scott Richard T., Seli Emre
Fertility and Sterility. 2021 115(4). p.957
Telomere length is associated with types of chromosome 21 nondisjunction: a new insight into the maternal age effect on Down syndrome birth
Ghosh Sujoy, Feingold Eleanor, Chakraborty Sumita, Dey Subrata Kumar
Human Genetics. 2010 127(4). p.403
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Shaw Jacquelyn, Blakemore Jennifer K., Keefe David L.
Exposure to air pollution and ovarian reserve parameters
Wieczorek Katarzyna, Szczęsna Dorota, Radwan Michał, Radwan Paweł, Polańska Kinga, Kilanowicz Anna, Jurewicz Joanna
Scientific Reports. 2024 14(1).
Age-associated changes in cumulus cells and follicular fluid: the local oocyte microenvironment as a determinant of gamete quality
Babayev Elnur, Duncan Francesca E
Biology of Reproduction. 2022 106(2). p.351
Telomere Length in Pig Sperm Is Related to In Vitro Embryo Development Outcomes
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Animals. 2022 12(2). p.204
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Epigenomics. 2018 10(4). p.499
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Fertility and Sterility. 2015 103(2). p.317
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Annual Review of Anthropology. 2020 49(1). p.317
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Oktay Kutluk, Turan Volkan, Titus Shiny, Stobezki Robert, Liu Lin
Biology of Reproduction. 2015 93(3).
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Journal of Assisted Reproduction and Genetics. 2023 40(8). p.1943
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Scientific Reports. 2017 7(1).
Leukocyte Telomere Length and Age at Menopause
Gray Kristen E., Schiff Melissa A., Fitzpatrick Annette L., Kimura Masayuki, Aviv Abraham, Starr Jacqueline R.
Epidemiology. 2014 25(1). p.139
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Ozturk Saffet
Biology of Reproduction. 2015 92(2).
DNA damage and repair in human oocytes and embryos: a review
Ménézo Yves, Dale Brian, Cohen Marc
Zygote. 2010 18(4). p.357

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