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RESEARCH ARTICLE (Open Access)

Testing and capturing difficult-to-access populations for syphilis control in Australia

Ei T. Aung A B * and Eric P. F. Chow A B C
+ Author Affiliations
- Author Affiliations

A Melbourne Sexual Health Centre, Alfred Health, Melbourne, Vic., Australia.

B School of Translational Medicine, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Vic., Australia.

C Centre for Epidemiology and Biostatistics, Melbourne, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Vic., Australia.




Dr Ei Aung is a sexual health physician and research fellow at the Melbourne Sexual Health Centre (MSHC) and Monash University. She completed her PhD, with a focus on epidemiology and novel interventions for syphilis control, particularly Treponema pallidum testing from asymptomatic mucosal sites and anal self-examination for early detection of anal syphilis in men who have sex with men.



Prof. Eric Chow is a sexually transmitted infections (STIs) epidemiologist and biostatistician at the MSHC and Monash University. His research program aims to improve the treatment, prevention and control of STIs, with a particular focus on gonorrhoea, syphilis and human papillomavirus.

* Correspondence to: eaung@mshc.org.au

Microbiology Australia https://doi.org/10.1071/MA24041
Submitted: 11 July 2024  Accepted: 7 August 2024  Published: 27 August 2024

© 2024 The Author(s) (or their employer(s)). Published by CSIRO Publishing on behalf of the ASM. This is an open access article distributed under the Creative Commons Attribution 4.0 International License (CC BY).

Abstract

Syphilis has significantly increased in the past decade in Australia, particularly among gay, bisexual and other men who have sex with men in urban areas, and Aboriginal and Torres Strait Islander peoples in regional and remote areas. Additionally, there has been a rise in cases among heterosexual men and women, including pregnant women, leading to a re-emergence of congenital syphilis. This resurgence underscores the ongoing need for effective public health interventions and innovative screening and detection methods. This article explores the epidemiology, screening and detection methods for syphilis, particularly focusing on difficult-to-access populations. Current screening strategies, including serology and molecular assays and recent changes in antenatal screening guidelines to prevent congenital syphilis are discussed. The article highlights the need for innovative, patient-centred detection methods and tailored interventions. New early detection methods, such as improved rapid diagnostic tests and digital health solutions, are discussed for their potential to increase screening uptake and early diagnosis. The findings underscore the importance of a multidisciplinary approach in syphilis control, combining universal and targeted interventions to effectively reduce transmission and improve public health outcomes.

Keywords: epidemiology, methods of syphilis detection, screening, sexually transmitted infections, STIs, syphilis, syphilis control, Treponema pallidum.

Biographies

MA24041_B1.gif

Dr Ei Aung is a sexual health physician and research fellow at the Melbourne Sexual Health Centre (MSHC) and Monash University. She completed her PhD, with a focus on epidemiology and novel interventions for syphilis control, particularly Treponema pallidum testing from asymptomatic mucosal sites and anal self-examination for early detection of anal syphilis in men who have sex with men.

MA24041_B2.gif

Prof. Eric Chow is a sexually transmitted infections (STIs) epidemiologist and biostatistician at the MSHC and Monash University. His research program aims to improve the treatment, prevention and control of STIs, with a particular focus on gonorrhoea, syphilis and human papillomavirus.

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