Lumpy skin disease: a significant threat to Australia
Kelly J. Stanger A * and Timothy R. Bowden AA CSIRO, Australian Centre for Disease Preparedness, Geelong, Vic. 3220, Australia.
Kelly Stanger is the Group leader for the newly established Lumpy Skin Disease Research group at the Australian Centre for Disease Preparedness (ACDP). She has over 20 years of research experience, predominantly working on the production limiting diseases and disorders affecting the red meat industries. Prior to commencing the Lumpy Skin Disease research role, Kelly was the Veterinary Services manager for ACDP overseeing the operation and research activities in the animal facilities. Before joining ACDP, she was a lecturer in Cattle Medicine and Production at the University of Melbourne, completed her PhD and worked as a veterinary consultant to the sheep and beef cattle industries through her work with the Mackinnon Group. She has a keen interest in biosecurity, animal welfare and production limiting diseases of livestock. |
Tim Bowden is a Senior Research Scientist and veterinarian with over 20 years of experience in virology and molecular biology, as well as diagnostic test development and validation, focusing on the pathogenesis, diagnosis, and control of infectious animal diseases. Since completing his PhD in 2004 Tim has worked at the CSIRO Australian Centre for Disease Preparedness (ACDP) on various projects, with both domestic and international collaborators, including to enhance the diagnostic capability for diseases caused by capripoxviruses (sheeppox, goatpox and lumpy skin disease) and foot-and-mouth disease. He has broad experience with pathogenesis and vaccine efficacy trials and, prior to joining the recently established Lumpy Skin Disease Research group, was the Team Leader (Serology) within the ACDP Diagnostic Emergency Response Laboratory. |
Microbiology Australia 43(4) 186-189 https://doi.org/10.1071/MA22061
Submitted: 10 November 2022 Accepted: 6 December 2022 Published: 22 December 2022
© 2022 The Author(s) (or their employer(s)). Published by CSIRO Publishing on behalf of the ASM. This is an open access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND)
Abstract
Lumpy skin disease, a mechanically transmitted poxvirus, causes severe disease in naïve populations of cattle and buffalo. It is characterised by development of multifocal cutaneous nodules and systemic illness with significant impacts on animal health, productivity, welfare and trade. Lumpy skin disease entered South-East Asia via Myanmar (November 2020) and later Thailand (March 2021), and has spread rapidly through the region reaching Indonesia in February 2022. This article provides a brief overview of current literature and its application to the Australian context including possible routes of entry, early detection and knowledge gaps that need to be addressed to improve preparedness and response capability.
Keywords: Australia, buffalo, capripoxvirus, cattle, emergency animal disease, lumpy skin disease, poxvirus, South‐East Asia, surveillance, vector.
References
[1] Tuppurainen ESM et al. (2018) General description of lumpy skin disease. In Lumpy Skin Disease. Springer, Cham.| Crossref |
[2] Tulman, ER et al.. (2001) Genome of lumpy skin disease virus. J Virol 75, 7122–7130.
| Genome of lumpy skin disease virus.Crossref | GoogleScholarGoogle Scholar |
[3] Tulman, ER et al.. (2002) The genomes of sheeppox and goatpox viruses. J Virol 76, 6054–6061.
| The genomes of sheeppox and goatpox viruses.Crossref | GoogleScholarGoogle Scholar |
[4] Babiuk, S et al.. (2008) Quantification of lumpy skin disease virus following experimental infection in cattle. Transbound Emerg Dis 55, 299–307.
| Quantification of lumpy skin disease virus following experimental infection in cattle.Crossref | GoogleScholarGoogle Scholar |
[5] Babiuk, S et al.. (2008) Capripoxviruses: an emerging worldwide threat to sheep, goats and cattle. Transbound Emerg Dis 55, 263–272.
| Capripoxviruses: an emerging worldwide threat to sheep, goats and cattle.Crossref | GoogleScholarGoogle Scholar |
[6] Tuppureinen E, Galon N (2016) Lumpy skin disease: current situation in Europe and neighbouring regions and necessary control measures to halt the spread in south-east Europe.
| Crossref |
[7] Animal Health Australia (2022) Response strategy: Lumpy skin disease (version 5.0), 5th edn. Australian Veterinary Emergency Plan (AUSVETPLAN). Available at https://animalhealthaustralia.com.au//wp-content/uploads/2022/09/AUSVETPLAN-Manuals-Response-Lumpy-skin-disease.pdf [accessed 10 November 2022]
[8] Animal Health Australia (2022) Emergency Animal Disease Response Agreement (EADRA). Available at https://animalhealthaustralia.com.au/eadra/ [accessed 10 November 2022]
[9] World Organisation for Animal Health (2022) Terrestrial Animal Health Code. Chapter 11.9. Infection with lumpy skin disease virus. OIE, Paris. Available at https://www.woah.org/fileadmin/Home/eng/Health_standards/tahc/current/chapitre_lsd.pdf [accessed 10 November 2022]
[10] Tuppurainen, ESM et al.. (2017) Review: Capripoxvirus diseases: current status and opportunities for control. Transbound Emerg Dis 64, 729–745.
| Review: Capripoxvirus diseases: current status and opportunities for control.Crossref | GoogleScholarGoogle Scholar |
[11] (2020) Lumpy skin disease epidemiological report IV: data collection and analysis. EFSA J 18, e06010.
| Lumpy skin disease epidemiological report IV: data collection and analysis.Crossref | GoogleScholarGoogle Scholar |
[12] Azeem, S et al.. (2022) Lumpy skin disease is expanding its geographic range: a challenge for Asian livestock management and food security. Vet J 279, 105785.
| Lumpy skin disease is expanding its geographic range: a challenge for Asian livestock management and food security.Crossref | GoogleScholarGoogle Scholar |
[13] Kumar, P et al.. (2021) Emergence and transboundary spread of lumpy skin disease in South Asia. Indian J Anim Sci 91, 507–517.
| Emergence and transboundary spread of lumpy skin disease in South Asia.Crossref | GoogleScholarGoogle Scholar |
[14] Kononova, S et al.. (2021) A lumpy skin disease virus which underwent a recombination event demonstrates more aggressive growth in primary cells and cattle than the classical field isolate. Transbound Emerg Dis 68, 1377–1383.
| A lumpy skin disease virus which underwent a recombination event demonstrates more aggressive growth in primary cells and cattle than the classical field isolate.Crossref | GoogleScholarGoogle Scholar |
[15] Vandenbussche, F et al.. (2022) Recombinant LSDV strains in Asia: vaccine spillover or natural emergence? Viruses 14, 1429.
| Recombinant LSDV strains in Asia: vaccine spillover or natural emergence?Crossref | GoogleScholarGoogle Scholar |
[16] Flannery, J et al.. (2022) A novel strain of lumpy skin disease virus causes clinical disease in cattle in Hong Kong. Transbound Emerg Dis 69, e336–e343.
| A novel strain of lumpy skin disease virus causes clinical disease in cattle in Hong Kong.Crossref | GoogleScholarGoogle Scholar |
[17] Sariya, L et al.. (2022) Molecular detection and characterization of lumpy skin disease viruses from outbreaks in Thailand in 2021. Transbound Emerg Dis 69, e2145–e2152.
| Molecular detection and characterization of lumpy skin disease viruses from outbreaks in Thailand in 2021.Crossref | GoogleScholarGoogle Scholar |
[18] White, JR et al.. (2021) Bluetongue virus serotype 12 enters Australia – a further incursion of novel western lineage genome segments. J Gen Virol 102, 001536.
| Bluetongue virus serotype 12 enters Australia – a further incursion of novel western lineage genome segments.Crossref | GoogleScholarGoogle Scholar |
[19] Eagles, D et al.. (2014) Long-distance aerial dispersal modelling of Culicoides biting midges: case studies of incursions into Australia. BMC Vet Res 10, 135.
| Long-distance aerial dispersal modelling of Culicoides biting midges: case studies of incursions into Australia.Crossref | GoogleScholarGoogle Scholar |
[20] Paslaru, AI et al.. (2022) Putative roles of mosquitoes (Culicidae) and biting midges (Culicoides spp.) as mechanical or biological vectors of lumpy skin disease virus. Med Vet Entomol 36, 381–389.
| Putative roles of mosquitoes (Culicidae) and biting midges (Culicoides spp.) as mechanical or biological vectors of lumpy skin disease virus.Crossref | GoogleScholarGoogle Scholar |
[21] Sanz-Bernardo, B et al.. (2022) The acquisition and retention of lumpy skin disease virus by blood-feeding insects is influenced by the source of virus, the insect body part, and the time since feeding. J Virol 96, e00751-22.
| The acquisition and retention of lumpy skin disease virus by blood-feeding insects is influenced by the source of virus, the insect body part, and the time since feeding.Crossref | GoogleScholarGoogle Scholar |
[22] El-Ansary, RE et al.. (2022) Isolation and molecular characterization of lumpy skin disease virus from hard ticks, Rhipicephalus (Boophilus) annulatus in Egypt. BMC Vet Res 18, 302.
| Isolation and molecular characterization of lumpy skin disease virus from hard ticks, Rhipicephalus (Boophilus) annulatus in Egypt.Crossref | GoogleScholarGoogle Scholar |
[23] Tuppurainen, ESM et al.. (2011) A potential role for ixodid (hard) tick vectors in the transmission of lumpy skin disease virus in cattle. Transbound Emerg Dis 58, 93–104.
| A potential role for ixodid (hard) tick vectors in the transmission of lumpy skin disease virus in cattle.Crossref | GoogleScholarGoogle Scholar |
[24] Lubinga, JC et al.. (2013) Detection of lumpy skin disease virus in saliva of ticks fed on lumpy skin disease virus-infected cattle. Exp Appl Acarol 61, 129–138.
| Detection of lumpy skin disease virus in saliva of ticks fed on lumpy skin disease virus-infected cattle.Crossref | GoogleScholarGoogle Scholar |
[25] Department of Agriculture Fisheries and Forestry. Differential diagnoses for lumpy skin disease. https://www.agriculture.gov.au/sites/default/files/documents/lsd-differential-chart.pdf (accessed 10 November 2022)
[26] Tuppurainen, E et al.. (2021) Review: Vaccines and vaccination against lumpy skin disease. Vaccines 9, 1136.
| Review: Vaccines and vaccination against lumpy skin disease.Crossref | GoogleScholarGoogle Scholar |
[27] Department of Agriculture Fisheries and Forestry (2022) National Lumpy Skin Disease Action Plan (Department of Agriculture Fisheries and Forestry, ed.). Available at https://www.agriculture.gov.au/sites/default/files/documents/lsd-national-action-plan.pdf [accessed 10 November 2022]
