Laboratory diagnosis of human infections transmitted by ticks, fleas, mites and lice in Australia
John Stenos A B and Stephen R Graves A CA Australian Rickettsial Reference Laboratory, University Hospital Geelong, Vic. 3220, Australia
B Email: JohnS@BarwonHealth.org.au
C Email: Graves.rickettsia@gmail.com
Microbiology Australia 39(4) 182-184 https://doi.org/10.1071/MA18059
Published: 30 October 2018
Abstract
A wide range of human pathogens (viruses, bacteria, protozoa) are transmitted by ticks, fleas, mites and lice worldwide. Some of these infections occur in Australia1, whereas others appear to be absent, although they may occur in returned travellers. The key to diagnosis is two-fold: recognition of the possibility of a vector-borne infection by the treating doctor and confirmation of the diagnosis in a diagnostic, microbiology laboratory. Laboratory diagnostic assays include culture (used rarely), nucleic acid amplification (used increasingly) and serology (used often).
References
[1] Graves, S.R. and Stenos, J. (2017) Tick-borne infectious diseases in Australia. Med. J. Aust. 206, 320–324.| Tick-borne infectious diseases in Australia.Crossref | GoogleScholarGoogle Scholar |
[2] Graves, S. (2013) Management of rickettsial diseases and Q fever. Med. Today 14, 65–69.
[3] Graves, S. and Stenos, J. (2009) Rickettsioses in Australia. Ann. N. Y. Acad. Sci. 1166, 151–155.
| Rickettsioses in Australia.Crossref | GoogleScholarGoogle Scholar |
[4] Graves, S. et al. (2016) Ixodes holocyclus tick-transmitted human pathogens in north-eastern New South Wales, Australia. Trop. Med. Infect. Dis. 1, 4.
[5] Wilson, P.A. et al. (2013) Queensland tick typhus: three cases with unusual clinical features. Intern. Med. J. 43, 823–825.
| Queensland tick typhus: three cases with unusual clinical features.Crossref | GoogleScholarGoogle Scholar |
[6] Stewart, A. et al. (2017) Epidemiology and characteristics of Rickettsia australis (Queensland Typhus) infection in hospitalised patients in north Brisbane, Australia. Trop. Med. Infect. Dis. 2, 10.
[7] Stewart, R.S. (1991) Flinders Island spotted fever: a newly recognised endemic focus of tick typhus in Bass Strait. Part 1. Clinical and epidemiological features. Med. J. Aust. 154, 94–99.
[8] Stenos, J. et al. (2003) Aponomma hydrosauri, the reptile-associated tick reservoir of Rickettsia honei on Flinders Island, Australia. Am. J. Trop. Med. Hyg. 69, 314–317.
| Aponomma hydrosauri, the reptile-associated tick reservoir of Rickettsia honei on Flinders Island, Australia.Crossref | GoogleScholarGoogle Scholar |
[9] Unsworth, N.B. et al. (2005) Not only ‘Flinders Island’ spotted fever. Pathology 37, 242–245.
| Not only ‘Flinders Island’ spotted fever.Crossref | GoogleScholarGoogle Scholar |
[10] Raby, E. et al. (2016) New foci of Spotted Fever Group rickettsiae including Rickettsia honei in Western Australia. Trop. Med. Infect. Dis. 1, 5.
[11] Unsworth, N.B. et al. (2007) Flinders Island Spotted Fever rickettsioses caused by ‘marmionii’ strain of Rickettsia honei, eastern Australia. Emerg. Infect. Dis. 13, 566–573.
| Flinders Island Spotted Fever rickettsioses caused by ‘marmionii’ strain of Rickettsia honei, eastern Australia.Crossref | GoogleScholarGoogle Scholar |
[12] Graves, S.R. et al. (1992) A case of murine typhus in Queensland. Med. J. Aust. 156, 650–651.
[13] Jones, S.L. et al. (2004) Murine typhus: the first reported case from Victoria. Med. J. Aust. 180, 482.
[14] Simon, N.G. et al. (2011) Murine typhus returns to New South Wales: a case of isolated meningoencephalitis with raised intracranial pressure. Med. J. Aust. 194, 652–654.
[15] Williams, M. et al. (2011) First probable Australian cases of human infection with Rickettsia felis (cat-flea typhus). Med. J. Aust. 194, 41–43.
[16] Teoh, Y.T. et al. (2017) Serological evidence of exposure to Rickettsia felis and Rickettsia typhi in Australian veterinarians. Parasit. Vectors 10, 129.
| Serological evidence of exposure to Rickettsia felis and Rickettsia typhi in Australian veterinarians.Crossref | GoogleScholarGoogle Scholar |
[17] Graves, S.R. and Islam, A. (2016) Endemic Q fever in New South Wales, Australia: a case series (2005-2013) Am. J. Trop. Med. Hyg. 95, 55–59.
| Endemic Q fever in New South Wales, Australia: a case series (2005-2013)Crossref | GoogleScholarGoogle Scholar |
[18] Vincent, G. et al. (2016) Novel genotypes of Coxiella burnetii identified in isolates from Australian Q fever patients. Int. J. Med. Microbiol. 306, 463–470.
| Novel genotypes of Coxiella burnetii identified in isolates from Australian Q fever patients.Crossref | GoogleScholarGoogle Scholar |
[19] Rathbone, P. et al. (1996) Bartonella (Rochalimaea) quintana causing fever and bacteraemia in an immunocompromised patient with non-Hodgkin’s lymphoma. Pathology 28, 80–83.
| Bartonella (Rochalimaea) quintana causing fever and bacteraemia in an immunocompromised patient with non-Hodgkin’s lymphoma.Crossref | GoogleScholarGoogle Scholar |
[20] Woolley, M.W. et al. (2007) Analysis of the first Australian strains of Bartonella quinana reveals unique genotypes. J. Clin. Microbiol. 45, 2040–2043.
| Analysis of the first Australian strains of Bartonella quinana reveals unique genotypes.Crossref | GoogleScholarGoogle Scholar |
[21] Saisongkorh, W. et al. (2009) Emerging Bartonella in humans and animals in Asia and Australia. J. Med. Assoc. Thai. 92, 707–731.
[22] Senanayake, S.N. et al. (2012) First report of human babesiosis in Australia. Med. J. Aust. 196, 350–352.
| First report of human babesiosis in Australia.Crossref | GoogleScholarGoogle Scholar |
[23] Wang, J.-M. et al. (2009) Diagnosis of Queensland Tick Typhus and African Tick Bite Fever by PCR of lesion swabs. Emerg. Infect. Dis. 15, 963–965.
| Diagnosis of Queensland Tick Typhus and African Tick Bite Fever by PCR of lesion swabs.Crossref | GoogleScholarGoogle Scholar |
[24] Graves, S. (2002) Imported rickettsial infections. Microbiol. Aust. 23, 33–34.
[25] Punj, P. et al. (2013) A pilgrim’s progress: severe Rickettsia conorii infection complicated by gangrene. Med. J. Aust. 198, 629–631.
| A pilgrim’s progress: severe Rickettsia conorii infection complicated by gangrene.Crossref | GoogleScholarGoogle Scholar |
[26] Aung, A.K. et al. (2014) Review article: rickettsial infections in southeast Asia: implications for local populace and febrile returned travellers. Am. J. Trop. Med. Hyg. 91, 451–460.
| Review article: rickettsial infections in southeast Asia: implications for local populace and febrile returned travellers.Crossref | GoogleScholarGoogle Scholar |
[27] Izzard, L. et al. (2010) Isolation of a novel Orientia species (O. chuto sp. nov.) from a patient infected in Dubai. J. Clin. Microbiol. 48, 4404–4409.
| Isolation of a novel Orientia species (O. chuto sp. nov.) from a patient infected in Dubai.Crossref | GoogleScholarGoogle Scholar |
[28] Burke, A. et al. (2015) Fever and rash from Timor: where have you been and when? Med. J. Aust. 203, 338–339.
| Fever and rash from Timor: where have you been and when?Crossref | GoogleScholarGoogle Scholar |
[29] Subedi, S. et al. (2015) First report of Lyme neuroborreliosis in a returned Australian traveller. Med. J. Aust. 203, 39–41.
| First report of Lyme neuroborreliosis in a returned Australian traveller.Crossref | GoogleScholarGoogle Scholar |
[30] Vincent, G.A. et al. (2015) Isolation of Coxiella burnetii from the serum of patients with acute Q fever. J. Microbiol. Methods 119, 74–78.
| Isolation of Coxiella burnetii from the serum of patients with acute Q fever.Crossref | GoogleScholarGoogle Scholar |
[31] Stenos, J. et al. (2010) Chapter 25: Rickettsia. In PCR for Clinical Microbiology (Schuller, M. ed.). Springer.
[32] Stenos, J. et al. (2010) Chapter 14: Coxiella burnetii. In PCR for Clinical Microbiology (Schuller, M. ed.). Springer.
[33] Graves, S. et al. (2006) Laboratory diagnosis of rickettsial infection. Aust. J. Med. Sci. 27, 39–44.