Chronic rhinosinusitis: a microbiome in dysbiosis and the search for alternative treatment options
Amanda Bordin A , Hanna E Sidjabat A D , Kyra Cottrell A and Anders Cervin A B C
+ Author Affiliations
- Author Affiliations
A The University of Queensland, UQ Centre for Clinical Research, Herston, Qld 4029, Australia
B The University of Queensland, School of Medicine, Brisbane, Qld, Australia
C Department of Otolaryngology, Head and Neck Surgery, Royal Brisbane and Women’s Hospital, Brisbane, Qld, Australia
D Corresponding author. Tel: +61 7 3346 6073, Fax: +61 7 3346 5595, Email: h.sidjabat@uq.edu.au
Microbiology Australia 37(3) 149-152 https://doi.org/10.1071/MA16051
Published: 24 August 2016
Abstract
Chronic rhinosinusitis (CRS) is a common chronic disease. While CRS is a multifactorial disease, many cases involve an imbalance in the sinus bacterial microbiome. This article reviews the composition of the healthy human sinus microbiome compared to the microbiome of CRS patients. Issues with current treatment options, particularly antibiotics, are discussed. Insights into the future of CRS treatment are also explored, principally with regards to probiotics.
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