Free Standard AU & NZ Shipping For All Book Orders Over $80!
Register      Login
Microbiology Australia Microbiology Australia Society
Microbiology Australia, bringing Microbiologists together
RESEARCH ARTICLE (Open Access)

Recent pandemics and informed predictions

Stanley Perlman A *
+ Author Affiliations
- Author Affiliations

A Department of Microbiology and Immunology, University of Iowa, Iowa City, IA 52242, USA.




Dr Perlman is a member of the Vaccines and Related Biological Products Advisory Committee (VRBPAC) of the US FDA, the WHO Technical Advisory Group on COVID-19 Vaccine Composition (TAG-CO-VAC) and the COVID-19 Advisory Committee on Immunization Practices (ACIP). His research focuses on coronavirus pathogenesis, including SARS (Severe Acute Respiratory Syndrome), MERS (Middle East Respiratory Syndrome) and COVID-19. His major interest now is olfactory dysfunction and neurological disease in mice and patients with COVID-19 and PASC (Post Acute Sequelae of COVID-19).

* Correspondence to: stanley-perlman@uiowa.edu

Microbiology Australia https://doi.org/10.1071/MA24057
Submitted: 11 August 2024  Accepted: 8 October 2024  Published: 28 October 2024

© 2024 The Author(s) (or their employer(s)). Published by CSIRO Publishing on behalf of the ASM. This is an open access article distributed under the Creative Commons Attribution 4.0 International License (CC BY).

Abstract

Although the COVID-19 pandemic had many deleterious effects, a positive aspect was that it forced us to ponder how we would approach a future epidemic or pandemic. Here, a set of predictions relevant to pandemic preparedness are discussed, based on our experience with the still ongoing COVID-19 pandemic.

Keywords: coronavirus, COVID-19, merbecovirus, misinformation, pandemic, sarbecovirus, SARS-CoV-2, surveillance, vaccines, zoonotic respiratory virus.

Biographies

MA24057_B1.gif

Dr Perlman is a member of the Vaccines and Related Biological Products Advisory Committee (VRBPAC) of the US FDA, the WHO Technical Advisory Group on COVID-19 Vaccine Composition (TAG-CO-VAC) and the COVID-19 Advisory Committee on Immunization Practices (ACIP). His research focuses on coronavirus pathogenesis, including SARS (Severe Acute Respiratory Syndrome), MERS (Middle East Respiratory Syndrome) and COVID-19. His major interest now is olfactory dysfunction and neurological disease in mice and patients with COVID-19 and PASC (Post Acute Sequelae of COVID-19).

References

Vlasova AN et al. (2022) Novel canine coronavirus isolated from a hospitalized pneumonia patient, east Malaysia. Clin Infect Dis 74, 446-454.
| Crossref | Google Scholar | PubMed |

Warr A et al. (2023) FCoV-23 causing FIP in a cat imported to the UK from Cyprus. Vet Rec 193, 414-415.
| Crossref | Google Scholar | PubMed |

Keusch GT et al. (2022) Pandemic origins and a One Health approach to preparedness and prevention: solutions based on SARS-CoV-2 and other RNA viruses. Proc Natl Acad Sci USA 119, e2202871119.
| Crossref | Google Scholar | PubMed |

Fehr AR, Perlman S (2015) Coronaviruses: an overview of their replication and pathogenesis. Methods Mol Biol 1282, 1-23.
| Crossref | Google Scholar | PubMed |

Kim Y et al. (2016) Reversal of the progression of fatal coronavirus infection in cats by a broad-spectrum coronavirus protease inhibitor. PLoS Pathog 12, e1005531.
| Crossref | Google Scholar | PubMed |

Saif LJ (2004) Animal coronavirus vaccines: lessons for SARS. Dev Biol 119, 129-140.
| Google Scholar | PubMed |

Ackermann M et al. (2020) Pulmonary vascular endothelialitis, thrombosis, and angiogenesis in COVID-19. N Engl J Med 383, 120-128.
| Crossref | Google Scholar | PubMed |

Arons MM et al. (2020) Presymptomatic SARS-CoV-2 infections and transmission in a skilled nursing facility. N Engl J Med 382, 2081-2090.
| Crossref | Google Scholar | PubMed |

Leung NHL et al. (2020) Respiratory virus shedding in exhaled breath and efficacy of face masks. Nat Med 26, 676-680.
| Crossref | Google Scholar | PubMed |

10  Zambrano LD et al. (2020) Update: characteristics of symptomatic women of reproductive age with laboratory-confirmed SARS-CoV-2 infection by pregnancy status – United States, January 22–October 3, 2020. MMWR Morb Mortal Wkly Rep 69, 1641-1647.
| Crossref | Google Scholar | PubMed |

11  Ying B et al. (2024) Mucosal vaccine-induced cross-reactive CD8(+) T cells protect against SARS-CoV-2 XBB.1.5 respiratory tract infection. Nat Immunol 25, 537-551.
| Crossref | Google Scholar | PubMed |

12  Kim W et al. (2022) Germinal centre-driven maturation of B cell response to mRNA vaccination. Nature 604, 141-145.
| Crossref | Google Scholar | PubMed |

13  Carmo Dos Santos M et al. (2024) Wastewater surveillance for viral pathogens: a tool for public health. Heliyon 10, e33873.
| Crossref | Google Scholar | PubMed |

14  Lindeboom RGH et al. (2024) Human SARS-CoV-2 challenge uncovers local and systemic response dynamics. Nature 631, 189-198.
| Crossref | Google Scholar | PubMed |

15  Memish ZA et al. (2020) Middle East respiratory syndrome. Lancet 395, 1063-1077.
| Crossref | Google Scholar | PubMed |