Bats, bacteria and their role in health and disease
Kristin MühldorferLeibniz Institute for Zoo and Wildlife Research
Department of Wildlife Diseases
Alfred-Kowalke-Str. 17, 10315 Berlin, Germany
Tel: +49 30 5168-215
Email: muehldorfer@izw-berlin.de
Microbiology Australia 38(1) 28-29 https://doi.org/10.1071/MA17009
Published: 9 February 2017
Abstract
Bats are ancient and among the most diverse mammals in terms of species richness, diet and habitat preferences, characteristics that may contribute to a high diversity of infectious agents. During the past two decades, the interest in bats and their microorganisms largely increased because of their role as reservoir hosts or carriers of important pathogens. Rapid advances in microbial detection and characterisation by high-throughput sequencing technologies have led to large genetic data sets but also improved our possibilities and speed of identifying unknown infectious agents. Assessing the risk of infectious diseases in bats and their pathological manifestation, however, is still challenging because of limited access to appropriate material and field data, and continuing limitations in wildlife diagnostics and the interpretation of genetic results. As a consequence, emerging pathogens can suddenly appear with devastating effects as happened for the white nose syndrome. To date, much research on bats and infectious agents still focusses on viruses, whilst the knowledge on bacteria and their role in disease is comparatively low.
References
[1] McKee, C.D. et al. (2016) Phylogenetic and geographic patterns of Bartonella host shifts among bat species. Infect. Genet. Evol. 44, 382–394.| Phylogenetic and geographic patterns of Bartonella host shifts among bat species.Crossref | GoogleScholarGoogle Scholar |
[2] Dietrich, M. et al. (2015) Leptospira and bats: story of an emerging friendship. PLoS Pathog. 11, e1005176.
| Leptospira and bats: story of an emerging friendship.Crossref | GoogleScholarGoogle Scholar |
[3] Mühldorfer, K. et al. (2014) Proposal of Vespertiliibacter pulmonis gen. nov., sp. nov. and two genomospecies as new members of the family Pasteurellaceae isolated from European bats. Int. J. Syst. Evol. Microbiol. 64, 2424–2430.
| Proposal of Vespertiliibacter pulmonis gen. nov., sp. nov. and two genomospecies as new members of the family Pasteurellaceae isolated from European bats.Crossref | GoogleScholarGoogle Scholar |
[4] Lei, B.R. and Olival, K.J. (2014) Contrasting patterns in mammal-bacteria coevolution: Bartonella and Leptospira in bats and rodents. PLoS Negl. Trop. Dis. 8, e2738.
| Contrasting patterns in mammal-bacteria coevolution: Bartonella and Leptospira in bats and rodents.Crossref | GoogleScholarGoogle Scholar |
[5] Mühldorfer, K. (2013) Bats and bacterial pathogens: a review. Zoonoses Public Health 60, 93–103.
| Bats and bacterial pathogens: a review.Crossref | GoogleScholarGoogle Scholar |
[6] Blehert, D.S. et al. (2014) Acute pasteurellosis in wild big brown bats (Eptesicus fuscus). J. Wildl. Dis. 50, 136–139.
| Acute pasteurellosis in wild big brown bats (Eptesicus fuscus).Crossref | GoogleScholarGoogle Scholar |
[7] Nakamura, S. et al. (2013) Outbreak of yersiniosis in Egyptian rousette bats (Rousettus aegyptiacus) caused by Yersinia pseudotuberculosis serotype 4b. J. Comp. Pathol. 148, 410–413.
| Outbreak of yersiniosis in Egyptian rousette bats (Rousettus aegyptiacus) caused by Yersinia pseudotuberculosis serotype 4b.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BC38bnt1ahuw%3D%3D&md5=28ba1061faaa34a4796b31c7fb4ee8d1CAS |
[8] Phillips, C.D. et al. (2012) Microbiome analysis among bats describes influences of host phylogeny, life history, physiology and geography. Mol. Ecol. 21, 2617–2627.
| Microbiome analysis among bats describes influences of host phylogeny, life history, physiology and geography.Crossref | GoogleScholarGoogle Scholar |
[9] Dietrich, M. et al. (2017) The excreted microbiota of bats: evidence of niche specialisation based on multiple body habitats. FEMS Microbiol. Lett. 364, .
| The excreted microbiota of bats: evidence of niche specialisation based on multiple body habitats.Crossref | GoogleScholarGoogle Scholar |
[10] Avena, C.V. (2016) Deconstructing the bat skin microbiome: influences of the host and the environment. Front. Microbiol. 7, 1753.
| Deconstructing the bat skin microbiome: influences of the host and the environment.Crossref | GoogleScholarGoogle Scholar |
