Protein microarrays in clinical microbiology

Abstract

Clinical microbiology laboratories have, in the past, broadly adopted new molecular biology techniques and automation. In the near future, the adoption of protein microarray technology has the potential to revolutionise the field in a manner similar to that of polymerase chain reaction (PCR). With the advantages of far greater sensitivity, parallel experimentation, reduced sample consumption and cost-per-test, the development of protein microarrays has come about through the realisation that mRNA levels do not necessarily correlate with protein expression.