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RESEARCH ARTICLE
Contents Vol 58(11)

Association analyses of polymorphisms in porcine MYF5 and MYOD1 genes with carcass traits

M. Liu A , J. Peng A , D. Q. Xu A , R. Zheng A , F. E. Li A , J. L. Li A , B. Zuo A , M. G. Lei A , Y. Z. Xiong A , C. Y. Deng A and S. W. Jiang A B
+ Author Affiliations
- Author Affiliations

A Agriculture Ministry Key Laboratory of Swine Genetics and Breeding, College of Animal Science and Technology, Huazhong Agricultural University, Wuhan 430070, P. R. China.

B Corresponding author. Email: jiangsiwen@mail.hzau.edu.cn

Australian Journal of Agricultural Research 58(11) 1040-1045 https://doi.org/10.1071/AR06420
Submitted: 25 December 2006  Accepted: 28 June 2007   Published: 26 November 2007

Abstract

The objective of this study was to assess the effect of polymorphisms of myogenic factor 5 (MYF5) and myogenic differentiation 1 (MYOD1) genes on carcass traits in pigs. PCR-RFLP was used to identify three and one SNP(s) from the MYF5 and the MYOD1 gene, respectively. Association analysis performed on the four polymorphisms in a series of three Large White × Meishan F2 populations totalling near 400 pigs showed: (1) an MYF5 exon 1 Hsp92II polymorphism causing a Met→Leu substitution was significantly associated with fat meat percentage, shoulder fat thickness, thorax-waist fat thickness, average backfat thickness and carcass length to 1st rib (P < 0.05); (2) an MYF5 exon 2 MspI polymorphism and an intron 1 HaeIII polymorphism, which were completely linked, were significantly associated with thorax-waist fat thickness, 6–7th rib fat thickness and carcass length to 1st rib (P < 0.05); (3) an MYOD1 intron 1 DdeI polymorphism was significantly associated with carcass length to 1st rib.

Additional keyword: pigs.


Acknowledgments

The project was supported by National Hi-Tech R&D Program of China (863 program, 2006AA10Z140), a China National High Technology R&D Program Grant (No. 2004AA213111) and a China National Key Foundation R&D Program Grant (No. 2006CB102102).


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