Australian Journal of Chemistry
Volume 76
Number 2 2023
The stories of four trailblazing Australian female chemists, Isabel Joy Bear, Enid Plante, Catherine Anne Money and Annabelle Duncan, who broke barriers and paved the way for future generations.
A microfluidic device was 3D printed for the determination of uric acid levels in urine. The device was coupled with a smartphone-based colorimetric method. Response surface methodology including central composed design was used to optimize experimental variables. This device shows promise for the evaluation of renal and kidney function.
Nanoscale SAPO-34 molecular sieves were synthesized by adding different types of seed into the hydrothermal synthesis system. The addition of seed into the initial gel during the synthetic process can facilitate the nucleation process and increase the crystallization rate effectively.
This work reports an enzyme-catalyzed cross-linking of injectable hydrogels. Tyramine-modified gelatin is used as the raw material, and horseradish peroxidase and H2O2 are added to catalyze the cross-linking to form an injectable hydrogel. The hydrogel can be used for drug release which will broaden the application of hydrogels in biomedical fields.
A series of novel anti-platelet aggregation 12-quinoline substituted andrographolide derivatives 9 were designed. Among these, compound 9o had the highest anti-platelet aggregation activity induced by ADP. Compound 9q showed the highest anti-platelet aggregation activity induced by thrombin. Most of the derivatives had no significant cytotoxicity.
, Anitha Kopinathan 
