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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
Australian Journal of Chemistry

Australian Journal of Chemistry

Volume 74 Number 10 2021

CH21089Chloramine-T in Organic Synthesis and Analysis of Organic Functional Groups: A Review

P. T. Sowmya 0000-0001-6321-7061, K. M. Lokanatha Rai, Anitha Sudhir and Sumana Y. Kotian
pp. 689-708
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The diverse nature of Chloramine-T, the sodium salt of N-chloro-p-toluenesulfonamide, abbreviated as CAT, acts as a source of halonium cation and nitrogen anion; acting as both base and nucleophile it reacts with broad range of functional groups and brings divergent molecular transformations to synthetic chemistry and also finds utility in analytical fields.

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Carbon onions are multilayered fullerenes that typically involve thousands of atoms. We evaluate the performance of force fields for their interaction energies. We proceed to show that the interaction energies between the layers of a giant ten-layered carbon onion increase linearly with the size of the carbon onion.

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A highly ordered Ag-TiO2 NPA SERS substrate could well adsorb organic molecules of R6G to achieve sensitive detection. The used SERS substrate of a R6G-Ag-TiO2 NPA could be regenerated through UV-excited photocatalytic degradation of R6G to achieve the self-cleaning and recycling application of the Ag-TiO2 NPA SERS substrate.

CH21178Determination of NADH by Surface Enhanced Raman Scattering Using Au@MB@Ag NPs

Yuqin Liao 0000-0002-5740-8838, Ruiyun You, Min Fan, Shangyuan Feng, Dechan Lu and Yudong Lu
pp. 722-729
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As an important biomarker, NADH is associated with breast cancer. In this paper, silver-plated gold core–shell nanoparticles containing Raman signalling molecules were synthesized. Based on SERS technology, the detection of NADH in complex biological samples of serum was achieved, offering the possibility to expand the early diagnosis of breast cancer.

CH21147Novel 4-Anilinoquinazoline Derivatives as Potent Anticancer Agents: Design, Synthesis, Cytotoxic Activity, and Docking Study

Fatemeh Azmian Moghadam, Sara Dabirian, Mahtab Ghasemi Dogaheh, Mohammad Mojabi, Fatemeh Yousefbeyk and Saeed Ghasemi 0000-0003-2007-2063
pp. 730-739
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Novel 4-anilinoquinazoline derivatives were synthesised and evaluated for their cytotoxicity on A431, HUVEC, and HU02 using MTT assay. Docking studies were done on synthesised compounds (8a8l) on EGFR and VEGFR-2. Furthermore, a wound healing assay was done to examine the effects of 8e, 8i, and 8l on cell migration.

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