Australian Journal of Chemistry
Volume 74 Number 10 2021
CH21089Chloramine-T in Organic Synthesis and Analysis of Organic Functional Groups: A Review
The diverse nature of Chloramine-T, the sodium salt of N-chloro-p-toluenesulfonamide, abbreviated as CAT, acts as a source of halonium cation and nitrogen anion; acting as both base and nucleophile it reacts with broad range of functional groups and brings divergent molecular transformations to synthetic chemistry and also finds utility in analytical fields.
Carbon onions are multilayered fullerenes that typically involve thousands of atoms. We evaluate the performance of force fields for their interaction energies. We proceed to show that the interaction energies between the layers of a giant ten-layered carbon onion increase linearly with the size of the carbon onion.
CH21172 Abstract | CH21172 Full Text | CH21172PDF (598 KB) | CH21172Supplementary Material (712 KB) Open Access Article
CH21142Fabrication of Highly Ordered Ag/TiO2 Nanopore Array as a Self-Cleaning and Recycling SERS Substrate
A highly ordered Ag-TiO2 NPA SERS substrate could well adsorb organic molecules of R6G to achieve sensitive detection. The used SERS substrate of a R6G-Ag-TiO2 NPA could be regenerated through UV-excited photocatalytic degradation of R6G to achieve the self-cleaning and recycling application of the Ag-TiO2 NPA SERS substrate.
As an important biomarker, NADH is associated with breast cancer. In this paper, silver-plated gold core–shell nanoparticles containing Raman signalling molecules were synthesized. Based on SERS technology, the detection of NADH in complex biological samples of serum was achieved, offering the possibility to expand the early diagnosis of breast cancer.
CH21147Novel 4-Anilinoquinazoline Derivatives as Potent Anticancer Agents: Design, Synthesis, Cytotoxic Activity, and Docking Study
Novel 4-anilinoquinazoline derivatives were synthesised and evaluated for their cytotoxicity on A431, HUVEC, and HU02 using MTT assay. Docking studies were done on synthesised compounds (8a–8l) on EGFR and VEGFR-2. Furthermore, a wound healing assay was done to examine the effects of 8e, 8i, and 8l on cell migration.
CH21218Thermodynamic Analysis of Tyrosyl-tRNA Synthetases Revealed Bacterial-Selective Tyrosine Derivatives
Substrate selectivity comparison of Escherichia coli and human tyrosyl-tRNA synthetases revealed two tyrosine derivatives exhibiting greater binding affinity to the bacterial enzyme.