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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

The Yeast-Mediated Reduction of Nitrostyrenes in Organic Solvent Systems

RR Bak, AF Mcanda, AJ Smallridge and MA Trewhella

Australian Journal of Chemistry 49(11) 1257 - 1260
Published: 1996

Abstract

A range of nitrostyrenes have been reduced with dried baker's yeast in an organic solvent system. It was found that the reduction proceeded smoothly to give the corresponding nitroalkanes in good yield and with higher efficiency than the corresponding aqueous reaction system. No evidence for reduction of the nitro group was observed. In the case of β-methyl nitrostyrenes, racemic mixtures were formed, and it was shown that this is not due to racemization of the product.

https://doi.org/10.1071/CH9961257

© CSIRO 1996

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