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Australian Journal of Chemistry Australian Journal of Chemistry Society
An international journal for chemical science
RESEARCH ARTICLE

Cetrimonium Nalidixate as a Multifunctional Inhibitor to Combat Biofilm Formation and Microbiologically Influenced Corrosion

Marianne Seter A , Melanie J. Thomson B , Alison Chong C , Douglas R. MacFarlane C and Maria Forsyth A D
+ Author Affiliations
- Author Affiliations

A Institute for Frontier Materials, Deakin University, Burwood, Vic. 3125, Australia.

B School of Medicine, Deakin University, Geelong, Vic. 3220, Australia.

C School of Chemistry, Monash University, Clayton, Vic. 3168, Australia.

D Corresponding author. Email: maria.forsyth@deakin.edu.au

Australian Journal of Chemistry 66(8) 921-929 https://doi.org/10.1071/CH13107
Submitted: 5 March 2013  Accepted: 2 May 2013   Published: 29 May 2013

Abstract

Microbial infection of surfaces and the formation of biofilms is a pervasive problem that appears in diverse fields from medical implants to corrosion of marine structures. We show here, for the first time, the multifunctional inhibitory effects of an environmentally friendly organic salt, cetrimonium nalidixate, a dual active compound based on concepts emerging from the active ionic liquids field. This salt when incorporated into a polyurethane coating leads to complete inhibition of microbiologically influenced corrosion in the presence of several bacteria strains commonly found in marine environments.


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