Immunization of Sheep With Larval Antigens of Lucilia cuprina
IJ O'Donnell, PE Green, JA Connell and PS Hopkins
Australian Journal of Biological Sciences
34(4) 411 - 418
Published: 1981
Abstract
Sheep were immunized with antigens extracted from third-instar larvae of L. cuprina. This procedure produced substantial titres of circulating antibody as measured by solid-phase radioimmunoassay or immunodiffusion or by both techniques. However, immunization did not confer protection against subsequent implant challenge with first-instar larvae. In vitro studies indicated that pooled sera from immunized sheep (mean immunodiffusion titre = 3) significantly reduced larval survival. Antigen specificity and the modulating effects of concomitant humoral responses to larval challenge are discussed in relation to the findings.https://doi.org/10.1071/BI9810411
© CSIRO 1981