Free Standard AU & NZ Shipping For All Book Orders Over $80!
Register      Login
Animal Production Science Animal Production Science Society
Food, fibre and pharmaceuticals from animals
RESEARCH ARTICLE

The impact of sequencing the bovine genome

J. E. Womack
+ Author Affiliations
- Author Affiliations

Department of Veterinary Pathobiology, College of Veterinary Medicine and Center for Animal Biotechnology and Genomics, Texas A&M University, College Station, TX 77843-4467 USA. Email: jwomack@cvm.tamu.edu

Australian Journal of Experimental Agriculture 46(2) 151-153 https://doi.org/10.1071/EA05229
Submitted: 9 August 2005  Accepted: 19 December 2005   Published: 3 March 2006

Abstract

Sequencing the bovine genome is the culmination of more than a decade of international collaboration to bring together resources to chart the genome of an economically important and biologically interesting species. Although considerable sequence is available at the publication of these proceedings, much work remains in annotation of the genome and the discovery of DNA polymorphisms within and between breeds. Nonetheless, the public availability of this sequence has already enhanced our ability to identify genes underlying phenotypes and to understand evolutionary relationships with other mammalian species. The accelerated rate of gene discovery in humans and laboratory animals following the sequencing of their genomes promises an exciting post-sequencing era for bovine genomics.


References


Band MR, Larson JH, Rebeiz M, Green CA, Heyen DW , et al. (2000) An ordered comparative map of the cattle and human genomes. Genome Research 10, 1359–1368.
Crossref | GoogleScholarGoogle Scholar | PubMed | (verified 3 January 2006)

Khatkar MS, Thomson PC, Tammen I, Raadsma HW (2004) Quantitative trait loci mapping in dairy cattle; review and meta-analysis. Genetics, Selection, Evolution. 36, 163–190.
Crossref | GoogleScholarGoogle Scholar | open url image1

Korstanje R, Paigen B (2002) From QTL to gene: the harvest begins. Nature Genetics 31, 235–236.
Crossref | GoogleScholarGoogle Scholar | PubMed | open url image1

Larkin DM, Everts van der Wind A, Rebeiz M, Schweister PA, Bachman S , et al. (2003) A cattle-human map built with cattle BAC-ends and human genome sequence. Genome Research 13, 1966–1972.
PubMed |
open url image1

Murphy WJ, Larkin DM, Everts-van der Wind A, Gurque G, Tesler G , et al. (2005) Dynamics of mammalian chromosome evolution inferred from multispecies comparative maps. Science 309, 613–617.
Crossref | GoogleScholarGoogle Scholar | PubMed | open url image1

Piper LR, Bindon BM (1982) The Booroola Merino and the performance of medium non-Peppin crosses at Armidale. In ‘The Booroola Merino’. (Eds LR Piper, BM Bindon, RD Nethery) pp. 9–19. (CSIRO Publishing: Melbourne)

Schibler L, Roig A, Mahe MF, Save JC, Gautier M, Taourit S, Boichard D, Eggen A, Cribiu EP (2004) A first generation bovine BAC-based physical map. Genetics, Selection, Evolution. 36, 105–122. open url image1

Thomas JW, Touchman JW, Blakesley RW, Bouffard GG, Beckstrom-Sternberg SM , et al. (2003) Comparative analyses of multi-species sequences from targeted genomic region. Nature 424, 788–793.
Crossref | GoogleScholarGoogle Scholar | PubMed | open url image1

Wilson T, Wu XY, Juengel JL, Ross IK, Lumsden JM , et al. (2001) Highly prolific Booroola sheep have a mutation in the intracellular kinase domain of bone morphogenetic protein IB receptor (ALK-6) that is expressed in both oocytes and granulosa cells. Biology of Reproduction 64, 1225–1235.
Crossref | GoogleScholarGoogle Scholar | PubMed | open url image1

Womack JE, Moll YD (1986) Gene map of the cow: conservation of linkage with mouse and man. The Journal of Heredity 77, 2–7.
PubMed |
open url image1

Womack JE, Johnson JS, Owens EK, Rexroad CE, Schlapfer J, Yang YP (1997) A whole-genome radiation hybrid panel for bovine gene mapping. Mammalian Genome 8, 854–856.
Crossref | GoogleScholarGoogle Scholar | PubMed | open url image1