Interaction and quantitative trait loci
O. MayoCSIRO Livestock Industries, PO Box 10041, Adelaide BC, SA 5000, Australia. Email: oliver.mayo@csiro.au
Australian Journal of Experimental Agriculture 44(11) 1135-1140 https://doi.org/10.1071/EA03240
Submitted: 18 November 2003 Accepted: 23 July 2004 Published: 14 December 2004
Abstract
Parallel searches for quantitative trait loci (QTL) for growth-related traits in different populations frequently detect sets of QTL that hardly overlap. Thus, many QTL potentially exist. Tools for the detection of QTL that interact are available and are currently being tested. Initial results suggest that epistasis is widespread. Modelling of the first recognised interaction, dominance, continues to be developed. Multigenic interaction appears to be a necessary part of any explanation. This paper covers an attempt to link some of these studies and to draw inferences about useful approaches to understanding and using the genes that influence quantitative traits.
Acknowledgments
I thank Reinhard Bürger, Carolyn Leach, Scott Newman and John Sved for helpful discussion and 2 referees and the editor for identifying many problems in the original draft.
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