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RESEARCH ARTICLE

Effect of dietary niacin supplementation on performance, total tract nutrient retention, carcass yield and meat lipid profile of growing turkeys

Tolulope Oluwadamilare Adebowale A B , Hongnan Liu A , Abimbola Oladele Oso B , Oyegunle Emmanuel Oke B , Tarique Hussain A , Adeyemi Mustapha Bamgbose B , Kang Yao A C and Yin Yulong A
+ Author Affiliations
- Author Affiliations

A Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, Hunan, China.

B College of Animal Science, Federal University of Agriculture, Abeokuta PMB 2240, Nigeria.

C Corresponding author. Email: yaokang@isa.ac.cn

Animal Production Science 59(6) 1098-1107 https://doi.org/10.1071/AN17806
Submitted: 14 November 2017  Accepted: 11 May 2018   Published: 17 September 2018

Abstract

A study was conducted to investigate the influence of dietary high or recommended nicotinic acid (niacin) supplementation on growth performance, total tract nutrient digestibility, hematology, serum chemistry, and lipoprotein concentrations in the serum and meat of growing turkeys. Turkeys were assigned to three treatments on weight equalisation basis with five replicates of eight turkeys in each group. Experimental diets were: no supplemental niacin (Control), a diet supplemented with 60 mg/kg niacin termed as recommended niacin supplementation and a diet supplemented with 180 mg/kg niacin termed as high niacin supplementation (HNS). The experiment lasted for the grower (Day 56–84) and finisher phases (Day 84–112) of the birds. Dietary inclusion of HNS increased (P < 0.01) bodyweight gain, metabolisable energy (Days 84 and 112), dressing percentage and retail cut parts of turkeys (Day 112) in relation to the Control-fed turkeys. Furthermore, least white blood cell count and higher concentrations of packed cell volume, red blood cells and hemoglobin (P < 0.01) were found in turkeys fed HNS on Days 84 and 112. Similarly, turkeys in the HNS group had improved serum constituents including serum protein, uric acid, aspartate aminotransferase, alanine aminotransferase, and alkaline phosphate. The blood and meat lipid profile analysis showed that low density lipoprotein and total cholesterol were least (P < 0.05) in turkeys fed HNS. Collectively, dietary high supplementation of niacin (180 mg/kg) improves production performances, reduces serum and meat fat content and improve indicators of stress resistance ability in growing turkeys.

Additional keywords: bodyweight, digestibility, meat cholesterol, serum contents.


References

AOAC (2000) ‘Official method of analysis of AOAC International.’ 17th edn. (Association of Official Analytical Chemists: Washington, DC)

Attia YA, Al-Harthi MA, Korish MA, Shiboob MM (2017) Fatty acid and cholesterol profiles, hypocholesterolemic, atherogenic, and thrombogenic indices of broiler meat in the retail market. Lipids in Health and Disease 16, 40

Batkowska J, Brodacki A, Zieba G, Horbanczuk JO, Lukaszewicz M (2015) Growth performance, carcass traits and physical properties of chicken meat as affected by genotype and production system. Archiv Fur Tierzucht-Archives of Animal Breeding 58, 325–333.

Biesalski HK (2005) Meat as a component of a healthy diet - are there any risks or benefits if meat is avoided in the diet? Meat Science 70, 509–524.
Meat as a component of a healthy diet - are there any risks or benefits if meat is avoided in the diet?Crossref | GoogleScholarGoogle Scholar |

Bogan KL, Brenner C (2008) Nicotinic acid nicotinamide and nicotinamide riboside: A molecular evaluation of NAD(+) precursor vitamins in human nutrition. Annual Review of Nutrition 28, 115–130.
Nicotinic acid nicotinamide and nicotinamide riboside: A molecular evaluation of NAD(+) precursor vitamins in human nutrition.Crossref | GoogleScholarGoogle Scholar |

Boyonoski AC, Spronck JC, Jacobs RM, Shah GM, Poirier GG, Kirkland JB (2002) Pharmacological intakes of niacin increase bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats. The Journal of Nutrition 132, 115–120.
Pharmacological intakes of niacin increase bone marrow poly(ADP-ribose) and the latency of ethylnitrosourea-induced carcinogenesis in rats.Crossref | GoogleScholarGoogle Scholar |

Cannan RK (1958) Proposal for a certified standard for use in hemoglobinometry - 2nd and final report. The Journal of Laboratory and Clinical Medicine 52, 471–476.

Cintra LTA, Samuel RO, Carrara Prieto AK, Sumida DH, Dezan-Junior E, Gomes-Filho JE (2017) Oral health, diabetes, and body weight. Archives of Oral Biology 73, 94–99.
Oral health, diabetes, and body weight.Crossref | GoogleScholarGoogle Scholar |

Cotter PF (2015) An examination of the utility of heterophil-lymphocyte ratios in assessing stress of caged hens. Poultry Science 94, 512–517.
An examination of the utility of heterophil-lymphocyte ratios in assessing stress of caged hens.Crossref | GoogleScholarGoogle Scholar |

Debut M, Berri C, Baeza E, Sellier N, Arnould C, Guemene D, Jehl N, Boutten B, Jego Y, Beaumont C, Le Bihan-Duval E (2003) Variation of chicken technological meat quality in relation to genotype and preslaughter stress conditions. Poultry Science 82, 1829–1838.
Variation of chicken technological meat quality in relation to genotype and preslaughter stress conditions.Crossref | GoogleScholarGoogle Scholar |

Denli M, Blandox JC, Guynot ME, Salado S, Perez JF (2009) Effects of dietary Afladetox on performance, serum biochemistry, histopathological changes, and aflatoxin residues in broilers exposed to aflatoxin B1. Poultry Science 881, 1444–1451.

Duclos MJ, Berri C, Le Bihan-Duval E (2007) Muscle growth and meat quality. Journal of Applied Poultry Research 16, 107–112.
Muscle growth and meat quality.Crossref | GoogleScholarGoogle Scholar |

Eggum BO, Jorgensen H, Danielsen V (1990) Lysine, methionine and threonine requirements for Weaned Pigs. Acta Agriculturae Scandinavica 40, 245–252.
Lysine, methionine and threonine requirements for Weaned Pigs.Crossref | GoogleScholarGoogle Scholar |

Elkin RG, Rogler JC (1990) Reduction of the cholesterol content of eggs by the oral-administration of lovastatin to laying hens. Journal of Agricultural and Food Chemistry 38, 1635–1641.
Reduction of the cholesterol content of eggs by the oral-administration of lovastatin to laying hens.Crossref | GoogleScholarGoogle Scholar |

Fernández C, Fraga MJ (1996) The effect of dietary fat inclusion on growth, carcass characteristics, and chemical composition of rabbits. Journal of Animal Science 74, 2088–2094.
The effect of dietary fat inclusion on growth, carcass characteristics, and chemical composition of rabbits.Crossref | GoogleScholarGoogle Scholar |

Fidele N, Joseph B, Emmanuel T, Theophile D (2017) Hypolipidemic, antioxidant and anti-atherosclerogenic effect of aqueous extract leaves of Cassia. occidentalis Linn (Caesalpiniaceae) in diet-induced hypercholesterolemic rats. BMC Complementary and Alternative Medicine 17, 76

Firman JD (1992) Amino acid digestibilities of soybean meal and meat meal in male and female turkeys of different ages1. Journal of Applied Poultry Research 1, 350–354.
Amino acid digestibilities of soybean meal and meat meal in male and female turkeys of different ages1.Crossref | GoogleScholarGoogle Scholar |

Flachowsky G (1993) Niacin in dairy and beef cattle nutrition. Archiv fur Tierernahrung 43, 195–213.
Niacin in dairy and beef cattle nutrition.Crossref | GoogleScholarGoogle Scholar |

Gille A, Bodor ET, Ahmed K, Offermanns S (2008) Nicotinic acid: pharmacological effects and mechanisms of action. Annual Review of Pharmacology and Toxicology 48, 79–106.
Nicotinic acid: pharmacological effects and mechanisms of action.Crossref | GoogleScholarGoogle Scholar |

Grewal RS, Tyagi N, Lamba JS, Ahuja CS, Saijpaul S (2014) Effect of bypass fat and niacin supplementation on the productive performance and blood profile of lactating crossbred cows under field conditions. Animal Nutrition and Feed Technology 14, 573–581.
Effect of bypass fat and niacin supplementation on the productive performance and blood profile of lactating crossbred cows under field conditions.Crossref | GoogleScholarGoogle Scholar |

Grummer RR, Carroll DJ (1988) A review of lipoprotein cholesterol-metabolism - importance to ovarian-function. Journal of Animal Science 66, 3160–3173.
A review of lipoprotein cholesterol-metabolism - importance to ovarian-function.Crossref | GoogleScholarGoogle Scholar |

Grundy SM, Mok HYI, Zech L, Berman M (1981) Influence of nicotinic-acid on metabolism of cholesterol and triglycerides in man. Journal of Lipid Research 22, 24–36.

Grünwaldt EG, Guevara JC, Estevez OR, Vicente A, Rousselle H, Alcuten N, Aguerregaray D, Stasi CR (2005) Biochemical and haematological measurements in beef cattle in Mendoza plain rangelands (Argentina). Tropical Animal Health and Production 37, 527–540.
Biochemical and haematological measurements in beef cattle in Mendoza plain rangelands (Argentina).Crossref | GoogleScholarGoogle Scholar |

Hemre GI, Lock EJ, Olsvik PA, Hamre K, Espe M, Torstensen BE, Silva J, Hansen AC, Waagbo R, Johansen JS, Sanden M, Sissener NH (2016) Atlantic salmon (Salmo salar) require increased dietary levels of B-vitamins when fed diets with high inclusion of plant based ingredients. PeerJ 4, e2493
Atlantic salmon (Salmo salar) require increased dietary levels of B-vitamins when fed diets with high inclusion of plant based ingredients.Crossref | GoogleScholarGoogle Scholar |

Hu M, Yamashita S, Masuda D, Poon E, Yang YL, Tomlinson B (2012) Effects of extended-release niacin on fasting lipoproteins, glucose and insulin levels in chinese patients with dyslipidaemia. Circulation 125, E910

Huff GR, Huff WE, Farnell MB, Rath NC, Solis De Los Santos F, Donoghue AM (2010) Bacterial clearance, heterophil function, and hematological parameters of transport-stressed turkey poults supplemented with dietary yeast extract. Poultry Science 89, 447–456.
Bacterial clearance, heterophil function, and hematological parameters of transport-stressed turkey poults supplemented with dietary yeast extract.Crossref | GoogleScholarGoogle Scholar |

Ilori BM, Peters SO, Yakubu A, Imumorin IG, Adeleke MA, Ozoje MO, Ikeobi CON, Adebambo OA (2011) Physiological adaptation of local, exotic and crossbred turkeys to the hot and humid tropical environment of Nigeria. Acta Agriculturae Scandinavica Section a-. Animal Science 61, 204–209.

Ivers DJ, Veum TL (2012) Effect of graded levels of niacin supplementation of a semipurified diet on energy and nitrogen balance, growth performance, diarrhea occurrence, and niacin metabolite excretion by growing swine. Journal of Animal Science 90, 282–288.
Effect of graded levels of niacin supplementation of a semipurified diet on energy and nitrogen balance, growth performance, diarrhea occurrence, and niacin metabolite excretion by growing swine.Crossref | GoogleScholarGoogle Scholar |

Javed MT, Ellahi M, Abbas N, Yasmin R, Mazhar M (2010) Effects of dietary chromium chloride, nicotinic acid and copper sulphate on meat of broilers. British Poultry Science 51, 354–360.
Effects of dietary chromium chloride, nicotinic acid and copper sulphate on meat of broilers.Crossref | GoogleScholarGoogle Scholar |

Jiang RR, Zhao GP, Chen JL, Zheng MQ, Zhao JP, Li P, Hu J, Wen J (2011) Effect of dietary supplemental nicotinic acid on growth performance, carcass characteristics and meat quality in three genotypes of chicken. Journal of Animal Physiology and Animal Nutrition 95, 137–145.
Effect of dietary supplemental nicotinic acid on growth performance, carcass characteristics and meat quality in three genotypes of chicken.Crossref | GoogleScholarGoogle Scholar |

Jiang RR, Zhao GP, Zhao JP, Chen JL, Zheng MQ, Liu RR, Wen J (2014) Influence of dietary nicotinic acid supplementation on lipid metabolism and related gene expression in two distinct broiler breeds of female chickens. Journal of Animal Physiology and Animal Nutrition 98, 822–829.
Influence of dietary nicotinic acid supplementation on lipid metabolism and related gene expression in two distinct broiler breeds of female chickens.Crossref | GoogleScholarGoogle Scholar |

Kamanna VS, Kashyap ML (2008) Mechanism of action of niacin. The American Journal of Cardiology 101, S20–S26.
Mechanism of action of niacin.Crossref | GoogleScholarGoogle Scholar |

Kause A, Mikkola L, Stranden I, Sirkko K (2015) Genetic parameters for carcass weight, conformation and fat in five beef cattle breeds. Animal 9, 35–42.
Genetic parameters for carcass weight, conformation and fat in five beef cattle breeds.Crossref | GoogleScholarGoogle Scholar |

Knopp RH, Alagona P, Davidson M, Goldberg AC, Kafonek SD, Kashyap M, Sprecher D, Superko HR, Jenkins S, Marcovina S (1998) Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia. Metabolism: Clinical and Experimental 47, 1097–1104.
Equivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemia.Crossref | GoogleScholarGoogle Scholar |

Kurtoglu F, Kurtoglu V, Nizamlioglu M (2004) Egg and serum cholesterol concentrations and zootechnical performances of layer hens fed with various levels of Niacin. Revue de Medecine Veterinaire 155, 393–400.

Leeson S, Caston LJ, Summers JD (1991) Response of laying hens to supplemental niacin. Poultry Science 70, 1231–1235.
Response of laying hens to supplemental niacin.Crossref | GoogleScholarGoogle Scholar |

Leibetseder J (1995) [Effects of L-carnitine in poultry.] Archiv fur Tierernahrung 48, 97–108.
[Effects of L-carnitine in poultry.]Crossref | GoogleScholarGoogle Scholar |

Li Y, Luo C, Wang J, Guo F (2017) Effects of different raising systems on growth performance, carcass, and meat quality of medium-growing chickens. Journal of Applied Animal Research 45, 326–330.
Effects of different raising systems on growth performance, carcass, and meat quality of medium-growing chickens.Crossref | GoogleScholarGoogle Scholar |

Lien TF, Horng YM, Yang KH (1999) Performance, serum characteristics, carcase traits and lipid metabolism of broilers as affected by supplement of chromium picolinate. British Poultry Science 40, 357–363.
Performance, serum characteristics, carcase traits and lipid metabolism of broilers as affected by supplement of chromium picolinate.Crossref | GoogleScholarGoogle Scholar |

Makkar SK, Rath NC, Packialakshmi B, Zhou ZY, Huff GR, Donoghue AM (2016) Nutritional supplement of hatchery eggshell membrane improves poultry performance and provides resistance against endotoxin stress. PLoS One 11, e0159433
Nutritional supplement of hatchery eggshell membrane improves poultry performance and provides resistance against endotoxin stress.Crossref | GoogleScholarGoogle Scholar |

Matte JJ, Corrent E, Simongiovanni A, Le Floc’h N (2016) Tryptophan metabolism, growth responses, and postprandial insulin metabolism in weaned piglets according to the dietary provision of niacin (vitamin B-3) and tryptophan. Journal of Animal Science 94, 1961–1971.
Tryptophan metabolism, growth responses, and postprandial insulin metabolism in weaned piglets according to the dietary provision of niacin (vitamin B-3) and tryptophan.Crossref | GoogleScholarGoogle Scholar |

Maurice DV, Jones JE, Lightsey SF, Rhoades JF, Hsu KT (1990) High dietary niacinamide and performance of male poults at 16 weeks of age. British Poultry Science 31, 795–802.
High dietary niacinamide and performance of male poults at 16 weeks of age.Crossref | GoogleScholarGoogle Scholar |

McKenney J (2003) Niacin for dyslipidemia: considerations in product selection. American Journal of Health-System Pharmacy 60, 995–1005.

McKenzie FE, Prudhomme WA, Magill AJ, Forney JR, Permpanich B, Lucas C, Gasser RA, Wongsrichanalai C (2005) White blood cell counts and malaria. The Journal of Infectious Diseases 192, 323–330.
White blood cell counts and malaria.Crossref | GoogleScholarGoogle Scholar |

Niu N, Yu YH, Wang Y, Wang LJ, Li Q, Guo LM (2009) Combined effects of niacin and chromium treatment on vascular endothelial dysfunction in hyperlipidemic rats. Molecular Biology Reports 36, 1275–1281.
Combined effects of niacin and chromium treatment on vascular endothelial dysfunction in hyperlipidemic rats.Crossref | GoogleScholarGoogle Scholar |

NRC (1994a) ‘Nutrient requirements of poultry.’ 9th rev. edn. (National Academy Press: Washington, DC)

NRC (1994b) ‘Nutrient requirements of poultry.’ 9th edn. (National Academy Press: Washington, DC)

Oke FO, Oso AO, Oduguwa OO, Jegede AV, Sudekum KH, Fafiolu AO, Pirgozliev V (2017) Growth, nutrient digestibility, ileal digesta viscosity, and energy metabolizability of growing turkeys fed diets containing malted sorghum sprouts supplemented with enzyme or yeast. Journal of Animal Physiology and Animal Nutrition 101, 449–456.
Growth, nutrient digestibility, ileal digesta viscosity, and energy metabolizability of growing turkeys fed diets containing malted sorghum sprouts supplemented with enzyme or yeast.Crossref | GoogleScholarGoogle Scholar |

Ouart MD, Harms RH, Wilson HR (1987) Effect of graded-levels of niacin in corn-soy and wheat-soy diets on laying hens. Poultry Science 66, 467–470.
Effect of graded-levels of niacin in corn-soy and wheat-soy diets on laying hens.Crossref | GoogleScholarGoogle Scholar |

Ponte PIP, Alves SP, Bessa RJB, Ferreira LMA, Gama LT, Bras JLA, Fontes CMGA, Prates Ja M (2008) Influence of pasture intake on the fatty acid composition, and cholesterol, tocopherols, and tocotrienols content in meat from free-range broilers. Poultry Science 87, 80–88.
Influence of pasture intake on the fatty acid composition, and cholesterol, tocopherols, and tocotrienols content in meat from free-range broilers.Crossref | GoogleScholarGoogle Scholar |

Rahman MS, Murphy AJ, Woollard KJ (2017) Effects of dyslipidaemia on monocyte production and function in cardiovascular disease. Nature Reviews. Cardiology 14, 387–400.
Effects of dyslipidaemia on monocyte production and function in cardiovascular disease.Crossref | GoogleScholarGoogle Scholar |

Real DE, Nelssen JL, Unruh JA, Tokach MD, Goodband RD, Dritz SS, Derouchey JM, Alonso E (2002) Effects of increasing dietary niacin on growth performance and meat quality in finishing pigs reared in two different environments. Journal of Animal Science 80, 3203–3210.
Effects of increasing dietary niacin on growth performance and meat quality in finishing pigs reared in two different environments.Crossref | GoogleScholarGoogle Scholar |

Ruiz N, Harms RH (1988) Niacin requirement of turkey poults fed a corn-soybean meal diet from 1 to 21 days of age. Poultry Science 67, 760–765.
Niacin requirement of turkey poults fed a corn-soybean meal diet from 1 to 21 days of age.Crossref | GoogleScholarGoogle Scholar |

Ruiz N, Harms RH (1990) The lack of response of broiler-chickens to supplemental niacin when fed a corn-soybean meal diet from 3-weeks to 7-weeks of age. Poultry Science 69, 2231–2234.
The lack of response of broiler-chickens to supplemental niacin when fed a corn-soybean meal diet from 3-weeks to 7-weeks of age.Crossref | GoogleScholarGoogle Scholar |

SAS (1999) ‘SAS/STAT user’s guide.’ (SAS Institute Inc.: Cary, NC)

Schalm OW, Jain NC, Qureshi MQ (1975) ‘Veterinary hematology.’ 3rd edn. (Lea and Fibinger: Philadelphia, PA)

Sibbald IR, Wolynetz MS (1989) Research note - pellet binder and steam pelleting as nitrogen-corrected true metabolizable energy contributors - an example of the statistics used to evaluate a component of a mixture. Poultry Science 68, 1299–1302.
Research note - pellet binder and steam pelleting as nitrogen-corrected true metabolizable energy contributors - an example of the statistics used to evaluate a component of a mixture.Crossref | GoogleScholarGoogle Scholar |

Skrivan M, Skrivanova V, Marounek M, Tumova E, Wolf J (2000) Influence of dietary fat source and copper supplementation on broiler performance, fatty acid profile of meat and depot fat, and on cholesterol content in meat. British Poultry Science 41, 608–614.
Influence of dietary fat source and copper supplementation on broiler performance, fatty acid profile of meat and depot fat, and on cholesterol content in meat.Crossref | GoogleScholarGoogle Scholar |

Sprecher D, Maxwell M, Goodman J, White B, Tang CM, Boullay V, De Gouville AC (2015) Discovery and characterization of GSK256073, a non-flushing hydroxy-carboxylic acid receptor 2 (HCA2) agonist. European Journal of Pharmacology 756, 1–7.
Discovery and characterization of GSK256073, a non-flushing hydroxy-carboxylic acid receptor 2 (HCA2) agonist.Crossref | GoogleScholarGoogle Scholar |

Svihus B, Hetland H, Choct M, Sundby F (2002) Passage rate through the anterior digestive tract of broiler chickens fed on diets with ground and whole wheat. British Poultry Science 43, 662–668.
Passage rate through the anterior digestive tract of broiler chickens fed on diets with ground and whole wheat.Crossref | GoogleScholarGoogle Scholar |

Tegge G (1985) ‘Bergmeyer, H. U. (Editor-in-Chief): Methods of enzymatic analysis (Methoden der enzymatischen analyse).’ 3rd edn. Volume III, enzymes 1: oxidoreductases, transferases. (Eds J Bergmeyer, M Graßl) (Verlag Chemie: Weinheim, Deerfield Beach, Basel)

Uijttenboogaart TG, Gerrits AR (1982). Method of dissection of broiler carcasses and description of parts. Beekbergen, Centrum voor Onderzoek en Voorlichting voor de Pluimveehouderij.

Varley JM, Macgregor HC, Erba HP (1980) Satellite DNA is transcribed on lampbrush chromosomes. Nature 283, 686–688.
Satellite DNA is transcribed on lampbrush chromosomes.Crossref | GoogleScholarGoogle Scholar |

Waldroup PW, Hellwig HM, Spencer GK, Smith NK, Fancher BI, Jackson ME, Johnson ZB, Goodwin TL (1985) The effects of increased levels of niacin supplementation on growth-rate and carcass composition of broiler-chickens. Poultry Science 64, 1777–1784.
The effects of increased levels of niacin supplementation on growth-rate and carcass composition of broiler-chickens.Crossref | GoogleScholarGoogle Scholar |

Wen C, Jiang XY, Ding LR, Wang T, Zhou YM (2017) Effects of dietary methionine on growth performance, meat quality and oxidative status of breast muscle in fast- and slow-growing broilers. Poultry Science 96, 1707–1714.

Whitehead C (2001) Nicotinic acid in poultry nutrition. Feed Mix, Doetinchem, The Netherlands, Misset International. Volume 9, number 1.

Wootton DM, Powell EC (1964) Parahalipegus (Gen N) for Halipegus Aspina Ingles 1936) Hemiuridae – Trematoda). The Journal of Parasitology 50, 662–663.
Parahalipegus (Gen N) for Halipegus Aspina Ingles 1936) Hemiuridae – Trematoda).Crossref | GoogleScholarGoogle Scholar |

Wu ZH, Zhao SP (2009) Niacin promotes cholesterol efflux through stimulation of the PPAR gamma-LXR alpha-ABCA1 pathway in 3T3–L1 adipocytes. Pharmacology 84, 282–287.
Niacin promotes cholesterol efflux through stimulation of the PPAR gamma-LXR alpha-ABCA1 pathway in 3T3–L1 adipocytes.Crossref | GoogleScholarGoogle Scholar |

Xia M-H, Huang X-L, Wang H-L, Jin M, Li M, Zhou Q-C (2015) Dietary niacin levels in practical diets for Litopenaeus vannamei to support maximum growth. Aquaculture Nutrition 21, 853–860.
Dietary niacin levels in practical diets for Litopenaeus vannamei to support maximum growth.Crossref | GoogleScholarGoogle Scholar |

Yang ZQ, Bao LB, Zhao XH, Wang CY, Zhou S, Wen LH, Fu CB, Gong JM, Qu MR (2016) Nicotinic acid supplementation in diet favored intramuscular fat deposition and lipid metabolism in finishing steers. Experimental Biology and Medicine 241, 1195–1201.
Nicotinic acid supplementation in diet favored intramuscular fat deposition and lipid metabolism in finishing steers.Crossref | GoogleScholarGoogle Scholar |

Zaina S, Lund G (2017) Connecting the dots between fatty acids, mitochondrial function, and DNA methylation in atherosclerosis. Current Atherosclerosis Reports 19, 36
Connecting the dots between fatty acids, mitochondrial function, and DNA methylation in atherosclerosis.Crossref | GoogleScholarGoogle Scholar |

Zerehdaran S, Vereijken ALJ, Van Arendonk Ja M, Van Der Waaij EH (2004) Estimation of genetic parameters for fat deposition and carcass traits in broilers. Poultry Science 83, 521–525.
Estimation of genetic parameters for fat deposition and carcass traits in broilers.Crossref | GoogleScholarGoogle Scholar |

Zuber T, Rodehutscord M (2017) Variability in amino acid digestibility and metabolizable energy of corn studied in cecectomized laying hens. Poultry Science 96, 1696–1706.