Role of oxidant–antioxidant balance in reproduction of domestic animals
Saranika Talukder A , Kendra L. Kerrisk A , Gianfranco Gabai B and Pietro Celi C D E
+ Author Affiliations
- Author Affiliations
A Faculty of Veterinary Science, The University of Sydney, Camden, NSW 2570, Australia.
B Dipartimento di Biomedicina Comparata e Alimentazione, Università di Padova, Italy.
C DSM Nutritional Products, Columbia, MD 21163, USA.
D Faculty of Veterinary and Agricultural Sciences, The University of Melbourne, Parkville, Vic. 3010, Australia.
E Corresponding author. Email: pietro.celi@dsm.com
Animal Production Science 57(8) 1588-1597 https://doi.org/10.1071/AN15619
Submitted: 16 September 2015 Accepted: 26 February 2017 Published: 5 April 2017
Abstract
Reproductive process leads to dynamic changes in metabolism and energy consumption, which may be responsible for the excessive production of free radicals (oxidants) that are generated during the physiological process of oxygen consumption. As the ovary is a metabolically active organ, it produces oxidants. Growing follicles, granulose cells of Graffian follicles and ovulated follicles all produce both enzymatic and non-enzymatic antioxidants to preserve themselves from the oxidative damage of oxidants. Oxidants and antioxidants are involved in several reproductive functions such as the regulation of follicular fluid environment, folliculogenesis, steroidogenesis, corpus luteum function, and luteolysis. In this article, the currently available literature is reviewed in relation to the roles of oxidants and oxidative stress in both normal and abnormal reproductive physiological processes.
Additional keywords: antioxidants, female reproduction, ovulation, oxidative stress.
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