The oral administration of meat and bone meal-derived protein fractions improved the performance of young broiler chicks
W. I. Muir A B , G. W. Lynch A , P. Williamson A and A. J. Cowieson A
+ Author Affiliations
- Author Affiliations
A Faculty of Veterinary Science, The University of Sydney, NSW 2570, Australia.
B Corresponding author. Email: wendy.muir@sydney.edu.au
Animal Production Science 53(5) 369-377 https://doi.org/10.1071/AN12209
Submitted: 18 June 2012 Accepted: 9 October 2012 Published: 7 February 2013
Abstract
A study was designed to assess the impact of water-soluble proteins and peptides extracted from meat and bone meal (MBM) on broiler chick performance, following their oral delivery during the early post-hatch period. Proteinaceous material was fractionated by size exclusion filtration into weight ranges of <3 kDa (Fraction 1; 0.5 mg protein/mL), 3–100 kDa (Fraction 2; 0.5 mg protein/mL) and >100 kDa (Fraction 3; 0.8 mg protein/mL), which formed the three protein fraction treatments. A total of 1 mL of each of the respective preparations was delivered orally via gavage over 4 days (0.25 µL each day) to Cobb broiler hatchlings. Three control groups: control–unhandled, control–phosphate-buffered saline and control–handled were also included. Chicks were grown to 30 days of age. Feed intake, chick weight gain and feed conversion ratio were determined from day old through to 29 days of age. On Days 10, 16, 23 and 30, the weight of the breast and the small intestine was determined from 10 birds/treatment. For all parameters measured there was no interaction between experimental week and protein fraction treatment. Chicks receiving Fraction 2 had a statistically significant increase in feed intake and weight gain (P = 0.012) compared with the control–unhandled chicks. Chicks receiving Fraction 2 also demonstrated a numerically higher final bodyweight. Mass spectrometric analysis of all three fractions revealed that they each contained a wide array of proteinacious material. The results of this study suggests the likelihood that protein or protein-derived fragment components within the 3–100 kDa molecular weight range of MBM can generate improvements in broiler chick production, and thus promote the need for further research to identify the specific protein(s) responsible for the observed positive growth effects.
References
Aird J, Spragg J (2003) Australian meat and bone meal: Nutritional Technical Review. Meat and Livestock Australia Ltd, North Sydney.Akin O, Temelli F, Koseoglu S (2012) Membrane applications in functional foods and nutraceuticals. Critical Reviews in Food Science and Nutrition 52, 347–371.
| Membrane applications in functional foods and nutraceuticals.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC38XivVCmtbY%3D&md5=0ff5962eb0430266ee93948e6bd695e7CAS |
Arihara K (2006) Functional properties of bioactive peptides derived from meat proteins. In ‘Advanced technologies for meat processing’. (Eds LML Nollet, F Toldrá) pp. 246–273. (CRC Press: Boca Raton, FL)
Association of Analytical Chemists (1990) ‘Official methods of analysis.’ 15th edn. (AOAC Press: Gaithersburg, MD)
Barnes DM, Kirby YK, Oliver KG (2001) Effects of biogenic amines on growth and the incidence of proventricular lesions in broiler chickens. Poultry Science 80, 906–911.
Bauchart C, Remond D, Chambon C, Patureau Mirand P, Savary-Auzeloux I, Reynes C, Morzel M (2006) Small peptides (<5 kDa) found in ready-to-eat beef meat. Meat Science 74, 658–666.
| Small peptides (<5 kDa) found in ready-to-eat beef meat.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28XoslOhtbo%3D&md5=c403471ffdc9682da9199154842a70b4CAS |
Bauchart C, Morzel M, Chambon C, Patureau Mirand P, Reynès C, Buffière C, Rémond D (2007a) Peptides reproducibly released by in vivo digestion of beef meat and trout flesh in pigs. The British Journal of Nutrition 98, 1187–1195.
| Peptides reproducibly released by in vivo digestion of beef meat and trout flesh in pigs.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXhtlSrt7w%3D&md5=5dd3bf5412a5e21789bda3d8b9c487cbCAS |
Bauchart C, Savary-Auzeloux I, Patureau Mirand P, Thomas E, Morzel M, Rémond D (2007b) Carnosine concentration of ingested meat affects carnosine net release into the portal vein of minipigs. The Journal of Nutrition 137, 589–593.
Bryden WL, Li X, Ravindran G, Hew LI, Ravindran V (2009) ‘Ileal digestible amino acid values in feedstuffs for poultry.’ Rural Industries Research and Development Corporation Publication 1440–6845; no. 09/071. (RIRDC: Barton, ACT)
Clare DA, Catignani GL, Swaisgood HE (2003) Biodefense properties of milk: the role of antimicrobial proteins and peptides. Current Pharmaceutical Design 9, 1239–1255.
| Biodefense properties of milk: the role of antimicrobial proteins and peptides.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3sXjslagt7g%3D&md5=3d7b812a67ef585c0283dbe359dd6cfdCAS |
den Brinker CA, Rayner CJ, Kerr MG, Bryden WL (2003) Biogenic amines in Australian by-product meals. Australian Journal of Experimental Agriculture 43, 113–119.
| Biogenic amines in Australian by-product meals.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3sXjt12hs7o%3D&md5=840e9642e34005a02c13c9ac16ce677cCAS |
Dozier WA, Kidd MT, Corzo A (2008) Dietary amino acid responses in broiler chickens. Applied Poultry Research 17, 157–167.
| Dietary amino acid responses in broiler chickens.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXos12js74%3D&md5=b14b1217e903bbf124c13ca6385483ccCAS |
Dziuba M, Darewicz M (2007) Food proteins as precursors of bioactive peptides – classification into families. Food Science & Technology International 13, 393–404.
| Food proteins as precursors of bioactive peptides – classification into families.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXltVKhtL4%3D&md5=81273dbfcffa6a14deaa54d834971b38CAS |
Fujita H, Yoshikawa M (1999) LKPNM: a prodrug-type ACE-inhibitory peptide derived from fish protein. Immunopharmacology 44, 123–127.
| LKPNM: a prodrug-type ACE-inhibitory peptide derived from fish protein.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK1MXotVKqs7c%3D&md5=2656e480a4fe3e6c8fa1becc840764caCAS |
Garcia RA (2007) New uses for rendered protein. Inform (Silver Spring, Md.) 18, 637–638.
Garcia RA, Phillips JG (2009) Physical distribution and characteristics of meat and bone meal protein. Journal of the Science of Food and Agriculture 89, 329–336.
| Physical distribution and characteristics of meat and bone meal protein.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXptVOmtw%3D%3D&md5=51f797b528735e9473a9bb14a9e9823dCAS |
Gatlin CL, Kleeman GR, Hays LG, Link AJ, Yates JR (1998) Protein identification at the low femtomole level from silver-stained gels using a new fritless electrospray interface for liquid chromatography-microspray and nanospray mass spectrometry. Analytical Biochemistry 263, 93–101.
| Protein identification at the low femtomole level from silver-stained gels using a new fritless electrospray interface for liquid chromatography-microspray and nanospray mass spectrometry.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaK1cXmtlygtL0%3D&md5=7c84f530253c589355c996006f3ea014CAS |
Hamilton CR (2002) Real and perceived issues involving animal proteins. In ‘Protein sources for the animal feed industry. FAO Expert Consultation and Workshop, Bangkok, 29 April–3 May’. pp. 255–276. (Food and Agriculture Organization of the United Nations: Rome, Italy)
Haque E, Chand R, Kapila S (2009) Biofunctional properties of bioactive peptides of milk origin. Food Reviews International 25, 28–43.
| Biofunctional properties of bioactive peptides of milk origin.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1MXht1agsQ%3D%3D&md5=775d3462123d75d91b9d6207860a9c43CAS |
Havenstein GB, Ferket PR, Quershi MA (2003) Carcass composition and yield of 1957 versus 2001 broilers when fed representative 1957 and 2001 broiler diets. Poultry Science 82, 1509–1518.
Kitts DD, Weiler K (2003) Bioactive proteins and peptides from food sources. Applications of bioprocesses used in isolation and recovery. Current Pharmaceutical Design 9, 1309–1323.
| Bioactive proteins and peptides from food sources. Applications of bioprocesses used in isolation and recovery.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3sXjslagtL8%3D&md5=76327d889d10bbac52af65faeaf9afbcCAS |
Li B, Chen F, Wang X, Ji B, Wu Y (2007) Isolation and identification of antioxidative peptides from porcine collagen hydrolysate by consecutive chromatography and electrospray ionization-mass spectrometry. Food Chemistry 102, 1135–1143.
| Isolation and identification of antioxidative peptides from porcine collagen hydrolysate by consecutive chromatography and electrospray ionization-mass spectrometry.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2sXht1Gksbc%3D&md5=cefbe1b5dcaaa81817053ed52f4c1b2fCAS |
Li X, Higgins TJV, Bryden WL (2006) Biological response of broiler chickens fed peas (Pisum sativum L.) expressing the bean (Phaseolus vulgaris L.) alpha-amylase inhibitor transgene. Journal of the Science of Food and Agriculture 86, 1900–1907.
| Biological response of broiler chickens fed peas (Pisum sativum L.) expressing the bean (Phaseolus vulgaris L.) alpha-amylase inhibitor transgene.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD28XpslWqtbg%3D&md5=ae3ed7567c3d3994f4b365c3b73f3500CAS |
Medenieks L, Vasiljevic T (2008) Underutilised fish as sources of bioactive peptides with potential health benefits. Food Australia 60, 581–588.
Meisel H (2007) Editorial: food-derived bioactive proteins and peptides as potential components of nutraceuticals. Current Pharmaceutical Design 13, 771–772.
| Editorial: food-derived bioactive proteins and peptides as potential components of nutraceuticals.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2sXlsVagtrc%3D&md5=21ad458102e5c64a98192733d2349915CAS |
Mine Y (2007) Egg proteins and peptides in human health-chemistry, bioactivity and production. Current Pharmaceutical Design 13, 875–884.
| Egg proteins and peptides in human health-chemistry, bioactivity and production.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2sXmtVWmur0%3D&md5=636e3f12304d727189073fa5764412c4CAS |
Mozdziak PE, Schultz E, Cassens RG (1997) Myonuclear accretion is a major determinant of avian skeletal muscle growth. The American Journal of Physiology 272, C565–C571.
Ohba R, Deguchi T, Kishikawa M, Arsyad F, Morimura S, Kida K (2003a) Physiological functions of enzymatic hydrolysates of collagen or keratin contained in livestock and fish waste. Food Science and Technology Research 9, 91–93.
| Physiological functions of enzymatic hydrolysates of collagen or keratin contained in livestock and fish waste.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3sXksFGgsrs%3D&md5=3a6c472b40b2df316d2eea29d244592cCAS |
Ohba R, Deguchi T, Kishikawa M, Morimura S, Suzuki I (2003b) Antioxidative effect of enzymatic hydrolysate of horn and hoof in rat. Food Science and Technology Research 9, 152–154.
| Antioxidative effect of enzymatic hydrolysate of horn and hoof in rat.Crossref | GoogleScholarGoogle Scholar |
Parsons CM, Castanon F, Han Y (1997) Protein and amino acid quality of meat and bone meal. Poultry Science 76, 361–368.
Pellegrini A (2003) Antimicrobial peptides from food proteins. Current Pharmaceutical Design 9, 1235–1238.
Ravindran V, Hendriks WH, Camden BJ, Thomas DV, Morel PCH, Butts CA (2002) Amino acid digestibility of meat and bone meals for broiler chickens. Australian Journal of Agricultural Research 53, 1257–1264.
| Amino acid digestibility of meat and bone meals for broiler chickens.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD38Xps1KgsL0%3D&md5=b42b5c3cbd63361b59c0814bde43f063CAS |
Robbins DH, Firman JD (2005) Evaluation of the metabolizable energy of meat and bone meal for chickens and turkeys by various methods. International Journal of Poultry Science 4, 633–638.
| Evaluation of the metabolizable energy of meat and bone meal for chickens and turkeys by various methods.Crossref | GoogleScholarGoogle Scholar |
Sakanaka S, Tachibana Y (2006) Active oxygen scavenging activity of egg-yolk protein hydrolysates and their effects on lipid oxidation in beef and tuna homogenates. Food Chemistry 95, 243–249.
| Active oxygen scavenging activity of egg-yolk protein hydrolysates and their effects on lipid oxidation in beef and tuna homogenates.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2MXhtVamsLvM&md5=8a7892571b3a9d5316cd3a2a53b24aeaCAS |
Shah NP (2000) Effects of milk-derived bioactives: an overview. The British Journal of Nutrition 84, S3–S10.
| Effects of milk-derived bioactives: an overview.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD3MXivFKitbw%3D&md5=0151c0240c314c9ff1a127f423f31390CAS |
Skurray GR, Herbert LS (1974) Batch dry rendering: influence of raw materials and processing conditions on meat meal quality. Journal of the Science of Food and Agriculture 25, 1071–1079.
| Batch dry rendering: influence of raw materials and processing conditions on meat meal quality.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DyaE2MXps1KmtQ%3D%3D&md5=f910fa2a56238f46450776fc24bb1a99CAS |
Smithers GW (2008) Whey and whey proteins – from ‘gutter to gold’. International Dairy Journal 18, 695–704.
| Whey and whey proteins – from ‘gutter to gold’.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXmvFWqsrs%3D&md5=6755e4f89c6656acf21a71cd0461d84eCAS |
Vercruysse L, Van Champ J, Smagghe G (2005) ACE inhibitory peptides derived from enzymatic hydrolysates of animal muscle protein: a review. Journal of Agricultural and Food Chemistry 53, 8106–8115.
| ACE inhibitory peptides derived from enzymatic hydrolysates of animal muscle protein: a review.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD2MXhtVWnurzF&md5=685f49412a256536585ef419e054c86fCAS |
Wallace RJ, Oleszek W, Franz C, Hahn I, Baser KHC, Mathe A, Teichmann K (2010) Dietary plant bioactives for poultry health and productivity. British Poultry Science 51, 461–487.
| Dietary plant bioactives for poultry health and productivity.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BC3cfnsFeltg%3D%3D&md5=8d31d1277175e35124cd4142190d2e9dCAS |
You S-J, Udenigwe CC, Aluko RE, Wu J (2010) Multifunctional peptides from egg white lysozyme. Food Research International 43, 848–855.
| Multifunctional peptides from egg white lysozyme.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BC3cXitV2ltLg%3D&md5=9569a25ff9ce65a137a21348d545924dCAS |
