Platypus Venom: a Review

Abstract

Platypuses (Ornithorhynchus anatinus) and other monotremes occupy an important position as an early offshoot from the evolutionary lineage leading from reptiles to mammals. One of the most intriguing characteristics of these mammals is that the males produce venom during the mating season. O. anatinus venom contains defensin-like peptide, C-type natriuretic peptide and nerve growth factor, as well as other unidentified fractions. These components of O. anatinus venom display similarity to components of the venom of other species such as sea anemones, snakes and shrews. Here we review available literature on O. anatinus venom and venom in other species. Further research into O. anatinus venom will offer some insight into the evolution and functions of venom components.