Pattern of hospital admissions and costs associated with acute rheumatic fever and rheumatic heart disease in Australia, 2012–2017
Ingrid Stacey A B * , Judith Katzenellenbogen A , Joseph Hung C , Rebecca Seth D , Carl Francia E F , Bradley MacDonald A G , James Marangou H I J , Kevin Murray A and Jeffrey Cannon KA
B
C
D
E
F
G
H
I
J
K
Abstract
This study aims to describe the pattern and trends in acute rheumatic fever (ARF)/rheumatic heart disease (RHD)-related hospitalisations and costs for Australians aged <65 years.
This retrospective linked data study measured trends in hospitalisations and costs for ARF, RHD and complications of ARF/RHD in Northern Territory, South Australia, Western Australia, Queensland and New South Wales between 1 July 2012 and 30 June 2017. Persons with ARF/RHD were identified from RHD registers and/or hospital records.
Over the 5-year study period, 791 children, aged <16 years (86.3% Indigenous), and 2761 adults, aged 16–64 years (44.8% Indigenous), were hospitalised for ARF, RHD or associated complications. On average there were 296 paediatric admissions per year, increasing 6.1% annually (95% CI: 2.4–9.6%, P = 0.001) and 1442 adult admissions per year, increasing 1.7% annually (95% CI: 0.1–3.4%, P = 0.03). Total 5-year costs were AU$130.6 m (AU$17.6 m paediatric, AU$113.0 m adult). Paediatric costs were mostly for ARF-related admissions whereas adult costs mostly involved valvular surgery. Emergency admissions and air ambulance transfers were common, particularly for non-metropolitan residents.
Successful ARF/RHD prevention would deliver significant hospital cost savings. Investment in primary and specialist health care in regional areas may reduce emergency admissions and regional transfers, further reducing hospital burden.
Keywords: Aboriginal and Torres Strait Islander health, acute rheumatic fever, diagnosis related groups, End RHD in Australia: Study of Epidemiology (ERASE), hospitalisations, linked data, rheumatic heart disease.
References
1 Katzenellenbogen JM, Bond-Smith D, Seth RJ, Dempsey K, Cannon J, Stacey I, et al. Contemporary Incidence and Prevalence of Rheumatic Fever and Rheumatic Heart Disease in Australia Using Linked Data: The Case for Policy Change. J Am Heart Assoc 2020; 9(19): 016851.
| Crossref | Google Scholar | PubMed |
2 Stacey I, Ralph A, de Dassel J, Nedkoff L, Wade V, Francia C, et al. The evidence that rheumatic heart disease control programs in Australia are making an impact. Aust N Z J Public Health 2023; 47(4): 100071.
| Crossref | Google Scholar | PubMed |
4 Doran J, Canty D, Dempsey K, Cass A, Kangaharan N, Remenyi B, et al. Surgery for rheumatic heart disease in the Northern Territory, Australia, 1997-2016: what have we gained? BMJ Glob Health 2023; 8(3): e011763.
| Crossref | Google Scholar | PubMed |
5 Stacey I, Hung J, Cannon J, Seth RJ, Remenyi B, Bond-Smith D, et al. Long-term outcomes following rheumatic heart disease diagnosis in Australia. Eur Heart J Open 2021; 1(3): oeab035.
| Crossref | Google Scholar | PubMed |
7 Cannon J, Bessarab DC, Wyber R, Katzenellenbogen JM. Public health and economic perspectives on acute rheumatic fever and rheumatic heart disease. Med J Aust 2019; 211(6): 250-52.
| Crossref | Google Scholar | PubMed |
8 Wyber R, Noonan K, Halkon C, Enkel S, Cannon J, Haynes E, et al. Ending rheumatic heart disease in Australia: the evidence for a new approach. Med J Aust 2020; 213(10): S3-S31.
| Crossref | Google Scholar | PubMed |
9 Rheumatic Fever Strategy (RFS) Joint Advisory Committee (JAC). Communiqué. 2022. Available at https://www.naccho.org.au/app/uploads/2022/06/24-February-2022-Joint-Advisory-Committee-Communique.pdf. [accessed August 2023].
10 Hardefeldt HA, Monteiro Fernandes A, Yan J, Francis JR. Acute Rheumatic Fever: Recent Advances. Pediatr Infect Dis J 2023; 42(2): e42-e44.
| Crossref | Google Scholar | PubMed |
11 Casey D, Turner P. Australia’s rheumatic fever strategy three years on. Med J Aust 2024; 220: 170-71.
| Crossref | Google Scholar | PubMed |
12 Katzenellenbogen JM, Bond-Smith D, Seth RJ, Dempsey K, Cannon J, Nedkoff L, et al. The End Rheumatic Heart Disease in Australia Study of Epidemiology (ERASE) Project: data sources, case ascertainment and cohort profile. Clin Epidemiol 2019; 11: 997-1010.
| Crossref | Google Scholar | PubMed |
13 Bond-Smith D, Seth R, De Klerk N, Nedkoff L, Anderson M, Hung J, et al. Development and Evaluation of a Prediction Model for Ascertaining Rheumatic Heart Disease Status in Administrative Data. Clin Epidemiol 2020; 12: 717-730.
| Crossref | Google Scholar | PubMed |
14 Katzenellenbogen JM, Nedkoff L, Cannon J, Kruger D, Pretty F, Carapetis JR, et al. Low positive predictive value of ICD-10 codes in relation to rheumatic heart disease: a challenge for global surveillance. Int Med J 2019; 49(3): 400-3.
| Crossref | Google Scholar | PubMed |
15 Christensen D, Davis G, Draper G, Mitrou F, McKeown S, Lawrence D. Evidence for the use of an algorithm in resolving inconsistent and missing Indigenous status in administrative data collections. Aust J Soc Issues 2014; 49(4): 423-43.
| Crossref | Google Scholar |
16 Independent Health and Aged Care Pricing Authority. NWAU calculators. 2024. Available at https://www.ihacpa.gov.au/health-care/pricing/nwau-calculators [accessed May 2020].
17 Stacey I, Seth R, Nedkoff L, Hung J, Wade V, Haynes E, et al. Rheumatic heart disease mortality in Indigenous and non-Indigenous Australians between 2013 and 2017. Heart 2023; 109: 1025-1033.
| Crossref | Google Scholar | PubMed |
18 National Aboriginal Community Controlled Health Organisation (NACCHO). NACCHO Key Facts. 2022. Available at https://www.naccho.org.au/app/uploads/2022/11/NACCHO_KeyFacts_infographics_A4_221115.pdf
19 Haynes E, Marawili M, Marika MB, Mitchell A, Walker R, Katzenellenbogen JM, et al. Living with Rheumatic Heart Disease at the Intersection of Biomedical and Aboriginal Worldviews. Int J Environ Res Public Health 2022; 19(8): 4650.
| Crossref | Google Scholar | PubMed |
20 Haynes E, Mitchell A, Enkel S, Wyber R, Bessarab D. Voices behind the Statistics: A Systematic Literature Review of the Lived Experience of Rheumatic Heart Disease. Int J Environ Res Public Health 2020; 17(4): 1347-72.
| Crossref | Google Scholar | PubMed |
21 Farnsworth JH, Krieg BM, Bennetts JS, Baker RA. Public Health Costs for Northern Territory and South Australian Cardiac Surgery Patients. Heart Lung Circ 2019; 28(11): 1720-27.
| Crossref | Google Scholar | PubMed |
22 Wyber R, Noonan K, Halkon C, Enkel S, Ralph A, Bowen A, et al. The RHD Endgame Strategy: The blueprint to eliminate rheumatic heart disease in Australia by 2031. Eur. J. Public Health 2020; 30: ckaa165.05.
| Crossref | Google Scholar |
23 Rwebembera J, Beaton AZ, de Loizaga SR, Rocha RTL, Doreen N, Ssinabulya I, et al. The Global Impact of Rheumatic Heart Disease. Curr Cardiol Rep 2021; 23(11): 160.
| Crossref | Google Scholar | PubMed |
24 Lopez D, Katzenellenbogen JM, Sanfilippo FM, Woods JA, Hobbs MS, Knuiman MW, et al. Transfers to metropolitan hospitals and coronary angiography for rural Aboriginal and non-Aboriginal patients with acute ischaemic heart disease in Western Australia. BMC Cardiovasc Disord 2014; 14: 58.
| Crossref | Google Scholar |
25 Haynes E, Katzenellenbogen JM, Noonan S, Stacey I, Mitchell AG, Wade V, et al. Is the Australian primary healthcare system ready for the Rheumatic Heart Disease Endgame strategy? Data synthesis and recommendations. Aust N Z J Public Health 2022; 46(5): 554-57.
| Crossref | Google Scholar | PubMed |
26 Coroners Court of Queensland. INQUEST INTO THE DEATHS OF: Yvette Michelle Wilma BOOTH, Adele Estelle SANDY, Shakaya GEORGE (“RHD Doomadgee Cluster”). Coroners Court of Queensland; 2023. Available at https://www.courts.qld.gov.au/__data/assets/pdf_file/0006/770109/cif-booth-sandy-george-20230630.pdf
27 Gardiner FW, de Graaff B, Bishop L, Campbell JA, Mealing S, Coleman M. Mental Health Crises in Rural and Remote Australia: An Assessment of Direct Medical Costs of Air Medical Retrievals and the Implications for the Societal Burden. Air Med J 2020; 39(5): 343-50.
| Crossref | Google Scholar | PubMed |
28 Commonwealth Government of Australia. Rheumatic Fever Strategy Federation Funding Agreement. 2022. Available at https://federalfinancialrelations.gov.au/agreements/rheumatic-fever-strategy
29 Roberts KV, Maguire GP, Brown A, Atkinson DN, Remenyi B, Wheaton G, et al. Rheumatic heart disease in Indigenous children in northern Australia: Differences in prevalence and the challenges of screening. Med J Aust 2015; 203(5): 221.
| Crossref | Google Scholar |