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Australian Health Review Australian Health Review Society
Journal of the Australian Healthcare & Hospitals Association
RESEARCH ARTICLE

Depression in palliative care patients: a survey of assessment and treatment practices of Australian and New Zealand palliative care specialists

Kay Porche A , Liz Reymond B , John O’ Callaghan C and Margaret Charles D E
+ Author Affiliations
- Author Affiliations

A Palliative Care Unit, Rockhampton Hospital, 2–80 Canning St, Rockhampton, Qld 4700, Australia. Email: kay.porche@health.qld.gov.au

B Brisbane South Palliative Care Collaborative, Griffith University School of Medicine, Metro South Palliative Care Service, Metro South Health, Queensland Health, PO Box 4069, Eight Mile Plains, Qld 4113, Australia. Email: elizabeth_reymond@health.qld.gov.au

C Consultancy and Liaison Psychiatry, Metro South Addiction and Mental Health Service, Metro South Health, Queensland Health, Princess Alexandra Hospital, Woolloongabba, Qld 4102, Australia. Email: john_ocallaghan@health.qld.gov.au

D School of Psychology A18, The University of Sydney, Sydney, NSW 2006, Australia.

E Corresponding author. Email: margaret.charles@sydney.edu.au

Australian Health Review 38(1) 44-50 https://doi.org/10.1071/AH13041
Submitted: 13 February 2013  Accepted: 30 September 2013   Published: 6 December 2013

Abstract

Objective To explore the practices of members of the Australian and New Zealand Society of Palliative Medicine (ANZSPM) in assessing and treating depression in palliative care patients.

Methods Semistructured questionnaires were forwarded to ANZSPM members in consecutive mail-outs to survey diagnostic and treatment practices for depression.

Results The response rate was 62.3%. The median prevalence of depression, as perceived by respondents, in the present respondent patient populations was 20% (range 0%–90%); 57.1% of respondents always assessed for depression, whereas 42.9% assessed for depression sometimes. The majority (98.9%) of respondents relied on clinical interviews to assess depression; non-somatic symptoms of the Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV) criteria were more useful than somatic symptoms. The depression screening tools most frequently used were one- and two-item questions. Pharmacological and non-pharmacological methods were used to treat depression, with selective serotonin reuptake inhibitors the most frequently prescribed medications. Psycho-educational and supportive counselling were the most frequently used non-pharmacological interventions. Nominated measures to augment depression management included improving access to psychiatry, psychology and other allied health services, the development of a screening tool specific to palliative care patients and associated guidelines for depression management.

Conclusions This is the first Australasian study to explore the practice of medical practitioners regarding depression in palliative patients. Incorporation of screening tool questions into palliative care assessment interviews may warrant future research.

What is known about the topic? Depression in palliative care patients has a negative impact on quality of life; however, little is known about how Australasian palliative care medical practitioners manage depression in this patient population.

What does this paper add? To the researchers’ knowledge, this is the first Australasian study that explores the practices of local palliative care specialists in the management of depression in palliative patients.

What are the implications for practitioners? Overall management of depression in palliative care populations by Australasian practitioners is similar to that of their European colleagues. Consensus is that for assessment of depression in palliative patients, non-somatic symptoms of DSM-IV criteria are more useful than somatic symptoms. Practitioners report the need for improved access to psychiatric, psychological and other support services, for a palliative care-specific depression screening tool and for depression management guidelines applicable to palliative care patients.


References

[1]  Smith EM, Gomm SA, Dickens CM. Assessing the independent contribution to quality of life from anxiety and depression in patients with advanced cancer. Palliat Med 2003; 17 509–13.
Assessing the independent contribution to quality of life from anxiety and depression in patients with advanced cancer.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD3svmsVOnuw%3D%3D&md5=69c8f73d3c31893cc1ef31317c5f887bCAS | 14526884PubMed |

[2]  Delgado-Guay M, Parsons HA, Li Z, Palmer JL, Bruera E. Symptom distress in advanced cancer patients with anxiety and depression in the palliative care setting. Support Care Cancer 2009; 17 573–9.
Symptom distress in advanced cancer patients with anxiety and depression in the palliative care setting.Crossref | GoogleScholarGoogle Scholar | 19005686PubMed |

[3]  Lloyd-Williams M, Dennis M, Taylor F. A prospective study to determine the association between physical symptoms and depression in patients with advanced cancer. Palliat Med 2004; 18 558–63.
A prospective study to determine the association between physical symptoms and depression in patients with advanced cancer.Crossref | GoogleScholarGoogle Scholar | 15453627PubMed |

[4]  Mystakidou K, Tsilika E, Parpa E, Athanasouli P, Galanos A, Anna P, et al Illness-related hopelessness in advanced cancer: influence of anxiety, depression and preparatory grief. Arch Psychiatr Nurs 2009; 23 138–47.
Illness-related hopelessness in advanced cancer: influence of anxiety, depression and preparatory grief.Crossref | GoogleScholarGoogle Scholar | 19327556PubMed |

[5]  Block SD. Psychological issues in end-of-life care. J Palliat Med 2006; 9 751–72.
Psychological issues in end-of-life care.Crossref | GoogleScholarGoogle Scholar | 16752981PubMed |

[6]  Irwin SA, Rao S, Bowler K, Palica J, Rao SS, Maglione JE, et al Psychiatric issues in palliative care: recognition of depression in patients enrolled in hospice care. J Palliat Med 2008; 11 158–63.
Psychiatric issues in palliative care: recognition of depression in patients enrolled in hospice care.Crossref | GoogleScholarGoogle Scholar | 18333728PubMed |

[7]  Lloyd-Williams M, Friedman T, Rudd N. A survey of antidepressant prescribing in the terminally ill. Palliat Med 1999; 13 243–8.
A survey of antidepressant prescribing in the terminally ill.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DyaK1Mvgtl2muw%3D%3D&md5=603eba39a966edd2d3e09806459dd5a4CAS | 10474711PubMed |

[8]  Block S. Assessing and managing depression in the terminally ill patient. Ann Intern Med 2000; 132 209–18.
Assessing and managing depression in the terminally ill patient.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD3c7gsVyjsQ%3D%3D&md5=0e60cb9b114537982134670b376e0233CAS | 10651602PubMed |

[9]  Wilson KG, Lander M, Chochinov HM. Diagnosis and management of depression in palliative care. In Chochinov HM, Breitbart W (Eds). Handbook of psychiatry in palliative medicine. 2nd ed. New York. Oxford University Press; 2009. p.39–68.

[10]  American Psychiatric Association. Diagnostic and statistical manual of mental disorders, 4th edn. Washington, DC: American Psychiatric Association; 1994.

[11]  Endicott J. Measurement of depression in patients with cancer. Cancer 1984; 53 2243–9.
| 1:STN:280:DyaL2c7ls1WjtQ%3D%3D&md5=5a8b5774c9f02eddcc5ad0c1ba994e14CAS | 6704912PubMed |

[12]  Rayner L, Loge JH, Wasteson E, Higginson IJ. The detection of depression in palliative care. Curr Opin Support Palliat Care 2009; 3 55–60.
The detection of depression in palliative care.Crossref | GoogleScholarGoogle Scholar | 19365162PubMed |

[13]  Le Fevre P, Devereux J, Smith S, Lawrie SM, Cornbleet M. Screening for psychiatric illness in the palliative care in-patient setting: a comparison between the Hospital Anxiety and Depression Scale and the General Health Questionnaire-12. Palliat Med 1999; 13 399–407.
Screening for psychiatric illness in the palliative care in-patient setting: a comparison between the Hospital Anxiety and Depression Scale and the General Health Questionnaire-12.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD3c7isVegtQ%3D%3D&md5=d2e7a4abd4c7a6803acb8c0487c4baaeCAS | 10659112PubMed |

[14]  Lloyd-Williams M, Friedman T, Rudd N. Criterion validation of the Edinburgh Postnatal Depression Scale as a screening tool for depression in patients with advanced metastatic cancer. J Pain Symptom Manage 2000; 20 259–65.
Criterion validation of the Edinburgh Postnatal Depression Scale as a screening tool for depression in patients with advanced metastatic cancer.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD3M%2FkvVWksw%3D%3D&md5=d38e610676c8543bedd7d7414f8aa0f1CAS | 11027907PubMed |

[15]  Lloyd-Williams M, Shiels C, Dowrick C. The development of the Brief Edinburgh Depression Scale (BEDS) to screen for depression in patients with advanced cancer. J Affect Disord 2007; 99 259–64.
The development of the Brief Edinburgh Depression Scale (BEDS) to screen for depression in patients with advanced cancer.Crossref | GoogleScholarGoogle Scholar | 17055588PubMed |

[16]  Chochinov HM, Wilson KG, Enns M, Lander S. ‘Are you depressed?’ Screening for depression in the terminally ill. Am J Psychiatry 1997; 154 674–6.
| 1:STN:280:DyaK2s3ot12qsg%3D%3D&md5=48b04ba7aacf9990dd79c3f13b8a882bCAS | 9137124PubMed |

[17]  Lloyd-Williams M, Spiller J, Ward J. Which depression screening tools should be used in palliative care? Palliat Med 2003; 17 40–3.
Which depression screening tools should be used in palliative care?Crossref | GoogleScholarGoogle Scholar | 12597464PubMed |

[18]  Akechi T, Okuyama T, Sugwara Y, Shima Y, Furukawa T. Screening for depression in terminally ill cancer patients in Japan. J Pain Symptom Manage 2006; 31 5–12.
Screening for depression in terminally ill cancer patients in Japan.Crossref | GoogleScholarGoogle Scholar | 16442477PubMed |

[19]  Mitchell AJ. Are one or two simple questions sufficient to detect depression in cancer and palliative care? A Bayesian meta-analysis. Br J Cancer 2008; 98 1934–43.
Are one or two simple questions sufficient to detect depression in cancer and palliative care? A Bayesian meta-analysis.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD1cznt1Kmsw%3D%3D&md5=ba0877a3e4ca8a23a17e910ba1566264CAS | 18506146PubMed |

[20]  Mystakidou K, Tsilika E, Parpa E, Smyrniotis V, Galanos A, Vlahos L. Beck Depression Inventory: exploring its psychometric properties in a palliative care population of advanced cancer patients. Eur J Cancer Care (Engl) 2007; 16 244–50.
Beck Depression Inventory: exploring its psychometric properties in a palliative care population of advanced cancer patients.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD2s3psl2hug%3D%3D&md5=5c79791b7605a7f54bff1faec5b416d7CAS |

[21]  Olden M, Rosenfeld B, Pessin H, Breitbart W. Measuring depression at the end of life. Is the Hamilton Depression Rating Scale a valid instrument? Assessment 2009; 16 43–54.
Measuring depression at the end of life. Is the Hamilton Depression Rating Scale a valid instrument?Crossref | GoogleScholarGoogle Scholar | 18676960PubMed |

[22]  Robinson J, Crawford G. Identifying palliative care patients with symptoms of depression: an algorithm. Palliat Med 2005; 19 278–87.
Identifying palliative care patients with symptoms of depression: an algorithm.Crossref | GoogleScholarGoogle Scholar | 15984500PubMed |

[23]  Sela RA. Screening for depression in palliative cancer patients attending a pain and symptom control clinic. Palliat Support Care 2007; 5 207–17.
Screening for depression in palliative cancer patients attending a pain and symptom control clinic.Crossref | GoogleScholarGoogle Scholar | 17969824PubMed |

[24]  Lees N, Lloyd-Williams M. Assessing depression in palliative care patients using the visual analogue scale: a pilot study. Eur J Cancer Care 1999; 8 220–3.
Assessing depression in palliative care patients using the visual analogue scale: a pilot study.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD3czosVKlsQ%3D%3D&md5=19dbd4c7841d708e10afad05d751ca3aCAS |

[25]  Rayner L, Price A, Hotopf M, Higginson IJ. Expert opinion on detecting and treating depression in palliative care: a Delphi study. BMC Palliat Care 2011; 10 10
Expert opinion on detecting and treating depression in palliative care: a Delphi study.Crossref | GoogleScholarGoogle Scholar | 21619580PubMed |

[26]  Mitchell AJ, Chan M, Bhatti H, Halton M, Grassi L, Johansen C. Prevalence of depression, anxiety and adjustment disorder in oncological, haematological and palliative-care settings: a meta-analysis of 94 interview-based studies. Lancet Oncol 2011; 12 160–74.
Prevalence of depression, anxiety and adjustment disorder in oncological, haematological and palliative-care settings: a meta-analysis of 94 interview-based studies.Crossref | GoogleScholarGoogle Scholar | 21251875PubMed |

[27]  Lawrie I, Lloyd-Williams M, Taylor F. How do palliative medicine physicians assess and manage depression. Palliat Med 2004; 18 234–8.
How do palliative medicine physicians assess and manage depression.Crossref | GoogleScholarGoogle Scholar | 15198136PubMed |

[28]  Vodermaier A, Linden W, Siu C. Screening for emotional distress in cancer patients: a systematic review of assessments. J Natl Cancer Inst 2009; 101 1464–88.
Screening for emotional distress in cancer patients: a systematic review of assessments.Crossref | GoogleScholarGoogle Scholar | 19826136PubMed |

[29]  Rayner L, Price A, Hotopf M, Higginson IJ. The development of evidence-based European guidelines on the management of depression in palliative cancer care. Eur J Cancer 2011; 47 702–12.
The development of evidence-based European guidelines on the management of depression in palliative cancer care.Crossref | GoogleScholarGoogle Scholar | 21211961PubMed |

[30]  Rayner L, Lee W, Price A, Monroe B, Sykes N, Hansford P, et al The clinical epidemiology of depression in palliative care and the predictive value of somatic symptoms: cross-sectional survey with four week follow-up. Palliat Med 2011; 25 229–41.
The clinical epidemiology of depression in palliative care and the predictive value of somatic symptoms: cross-sectional survey with four week follow-up.Crossref | GoogleScholarGoogle Scholar | 21228092PubMed |

[31]  Rodin G, Lloyd N, Katz M, Green E, Mackay JA, Wong RKS. The treatment of depression in cancer patients: a systematic review. Support Care Cancer 2007; 15 123–36.
The treatment of depression in cancer patients: a systematic review.Crossref | GoogleScholarGoogle Scholar | 17058100PubMed |

[32]  Rayner L, Price A, Evans A, Valsraj K, Higginson IJ, Hotopf M. Antidepressants for depression in physically ill people. Cochrane Database Syst Rev 2010; 3 CD007503
Antidepressants for depression in physically ill people.Crossref | GoogleScholarGoogle Scholar | 20238354PubMed |

[33]  Rayner L, Price A, Evans A, Valsraj K, Hotopf M, Higginson IJ. Antidepressants for the treatment of depression in palliative care: systematic review and meta-analysis. Palliat Med 2011; 25 36–51.
Antidepressants for the treatment of depression in palliative care: systematic review and meta-analysis.Crossref | GoogleScholarGoogle Scholar | 20935027PubMed |

[34]  Department of Health and Ageing (DOHA). Pharmaceutical benefits scheme. Canberra: DOHA; 2011. Available at http//www.pbs.gov.au/pbs/home [verified 14 May 2011]

[35]  Pharmaceutical Management Agency of New Zealand. Pharmac. 2011. Available athttp//www.pharmac.govt.nz/healthpros/Schedule [verified 14 May 2011]

[36]  Horne-Thompson A, Grocke D. The effect of music therapy on anxiety in patients who are terminally ill. J Palliat Med 2008; 11 582–90.
The effect of music therapy on anxiety in patients who are terminally ill.Crossref | GoogleScholarGoogle Scholar | 18454611PubMed |

[37]  Roth AJ, Massie MJ. Anxiety and its management in advanced cancer. Curr Opin Support Palliat Care 2007; 1 50–6.
Anxiety and its management in advanced cancer.Crossref | GoogleScholarGoogle Scholar | 18660725PubMed |

[38]  Price A, Hotopf M. The treatment of depression in patients with advanced cancer undergoing palliative care. Curr Opin Support Palliat Care 2009; 3 61–6.
The treatment of depression in patients with advanced cancer undergoing palliative care.Crossref | GoogleScholarGoogle Scholar | 19365163PubMed |

[39]  Doyle D, Hanks G, Cherny N, Calman K, eds. Oxford textbook of palliative medicine, 3rd edn. Oxford: Oxford University Press; 2005.