Unprecedented increase in syphilis cases among heterosexual men and women in Japan, 2021–2022
Ayu Kasamatsu A , Takuri Takahashi A , Yuzo Arima A * , Miyako Otsuka A , Takeshi Arashiro A , Hanae Ito B , Sakiko Tabata B , Takuya Yamagishi C and Motoi Suzuki AA Center for Surveillance, Immunization and Epidemiologic Research, National Institute of Infectious Diseases, Tokyo, Japan.
B Field Epidemiology Training Program, National Institute of Infectious Diseases, Tokyo, Japan.
C Center for Field Epidemic Intelligence, Research and Professional Development, National Institute of Infectious Diseases, Tokyo, Japan.
Sexual Health 20(4) 370-372 https://doi.org/10.1071/SH23031
Submitted: 14 February 2023 Accepted: 19 May 2023 Published: 7 June 2023
© 2023 The Author(s) (or their employer(s)). Published by CSIRO Publishing
Abstract
Based on national surveillance data, we describe an unprecedented increase in syphilis case reports in Japan, with a surge in 2021–2022 reaching 10 141 cases in Week 42, 2022, a 1.7-fold increase over the same period in 2021. This already represented the highest annual case count in nearly half a century; by Week 52, 2022, the number reached 12 966, far surpassing the 7978 cases in 2021. Predominantly affecting heterosexual men and young women, the proportionate increase in primary and secondary syphilis cases suggests a true increase in incidence. The syphilis surge during the pandemic poses a serious public health concern and underscores the importance of adequate testing and preventive measures.
Keywords: age distribution, Asia, congenital, epidemiology, Japan, sexually transmitted diseases, surveillance, syphilis.
References
[1] National Institute of Infectious Diseases. Reporting criteria for syphilis. Infectious Agents Surveillance Report; 2015. Available at https://www.niid.go.jp/niid/images/iasr/36/420/de4201.pdf [cited 11 October 2022].[2] National Institute of Infectious Diseases. Infectious disease weekly report week 42; 2022. Available at https://www.niid.go.jp/niid/ja/syphilis-m-3/syphilis-idwrc/11612-idwrc-2242.html [cited 7 November 2022].
[3] Kanai M, Arima Y, Nishiki S, Shimuta K, Itoda I, Matsui T, et al. Molecular typing and macrolide resistance analyses of Treponema pallidum in heterosexuals and men who have sex with men in Japan, 2017. J Clin Microbiol 2019; 57 e01167–18.
| Molecular typing and macrolide resistance analyses of Treponema pallidum in heterosexuals and men who have sex with men in Japan, 2017.Crossref | GoogleScholarGoogle Scholar |
[4] Takahashi T, Arima Y, Yamagishi T, Nishiki S, Kanai M, Ishikane M, et al. Rapid increase in reports of syphilis associated with men who have sex with women and women who have sex with men, Japan, 2012 to 2016. Sex Transm Dis 2018; 45 139–43.
| Rapid increase in reports of syphilis associated with men who have sex with women and women who have sex with men, Japan, 2012 to 2016.Crossref | GoogleScholarGoogle Scholar |
[5] Ministry of Health Labour and Welfare. Vital statistics. Available at https://www.mhlw.go.jp/toukei/list/81-1a.html [cited 7 April 2023].
[6] National Institute of Infectious Diseases. Notification trends among syphilis cases in Japan; 2022. Available at https://www.niid.go.jp/niid/ja/syphilis-m/syphilis-trend.html [cited 17 April 2023].
[7] National Institute of Infectious Diseases. Pregnant cases and female commercial sex worker cases among reported syphilis cases based on the national epidemiological surveillance of infectious diseases system, 2019–2021; 2022. Available at https://www.niid.go.jp/niid/ja/syphilis-m-3/syphilis-idwrs/11654-syphilis-20221130.html [cited 3 December 2022].
[8] Sudo K, Sano T, Kondo M, Imai M, Kato S, Imamura A. Health labour sciences research grant. Research report for improvement of HIV testing system and effective recommendation of HIV testing, survey on testing situation and accuracy of HIV mailed testing; 2021. Available at https://mhlw-grants.niph.go.jp/system/files/report_pdf/202120002A-buntan6.pdf [cited 21 November 2022].