Factors influencing sexually transmissible infection disclosure to male partners by HIV-positive pregnant women in Pretoria townships, South Africa: a qualitative study
Joseph Daniels A E , Lindsey De Vos B , Winta Mogos C , Dawie Olivier B , Simukai Shamu B , Maanda Mudau B , Jeffrey Klausner D and Andrew Medina-Marino BA Charles Drew University, 1731 E. 120th Street, Los Angeles, CA 90059, USA.
B Foundation for Professional Development, 173 Mary Road, Die Wilgers, Pretoria, 0184, South Africa.
C Program in Public Health, 653 E. Peltason Drive, University of California Irvine, Irvine, CA 92617, USA.
D UCLA CARE Center, 1399 S. Roxbury Drive, Suite 100, Los Angeles, CA 90035, USA.
E Corresponding author. Email: josephdaniels@cdrewu.edu
Sexual Health 16(3) 274-281 https://doi.org/10.1071/SH18177
Submitted: 11 October 2018 Accepted: 19 February 2019 Published: 10 May 2019
Abstract
Background: Sexually transmissible infections (STI) may increase the risk of mother-to-child transmission (MTCT) of HIV. However, diagnostic testing and targeted treatment of STI (STI-TT) during pregnancy is not standard care in South Africa. Methods: A qualitative study was nested in a STI-TT intervention to investigate motivating and enabling factors associated with STI test results disclosure to sexual partners. A semi-structured interview protocol covered partner communication, HIV and STI disclosure, financial security and relationships dynamics. Interviews were conducted in participants’ preferred language, audio-recorded, transcribed into English and analysed using a constant comparison approach. The study was conducted in two townships in Pretoria, South Africa. Results: Twenty-eight HIV-positive pregnant women were interviewed. Based on the interviews, two disclosure experiences for women were identified – those with vulnerable experiences and those with self-enabling experiences within their partnerships. Vulnerable women discussed intimate partner violence (IPV) and fear of relationship dissolution as factors influencing their test result disclosure. Self-enabled women discussed their ability to talk with their partners about STI and HIV infections and the influence of multiple concurrent partnerships in the acquisition of HIV/STIs. Both groups of women were concerned about men’s health behaviours, and all cited the health and development of their unborn child as a key motivator for test result disclosure. Conclusions: Improved counselling and support for pregnant women to disclose their STI test results to their partners may improve the impact of STI diagnostic testing during pregnancy by improving partner treatment uptake and thus reducing the risk of re-infection.
Additional keywords: STI disclosure, HIV, pregnancy, antenatal care, diagnostic screening of STIs.
References
[1] Weiss SM, Karl P, Olga VL, Shikwane ME, Ryan C, Jones DL. Improving PMTCT uptake in rural South Africa. J Int Assoc Provid AIDS Care 2014; 13 269–76.| Improving PMTCT uptake in rural South Africa.Crossref | GoogleScholarGoogle Scholar | 23778240PubMed |
[2] Mate KS, Bennett B, Mphatswe W, Barker P, Rollins N. Challenges for routine health system data management in a large public programme to prevent mother-to-child HIV transmission in South Africa. PLoS One 2009; 4 e5483
| Challenges for routine health system data management in a large public programme to prevent mother-to-child HIV transmission in South Africa.Crossref | GoogleScholarGoogle Scholar | 19434234PubMed |
[3] Adachi K, Klausner JD, Bristow CC, Xu J, Ank B, Morgado MG, Watts DH, Weir F, Persing D, Mofenson LM, Veloso VG, Pilotto JH, Joao E, Nielsen-Saines K, for the NICHD HPTN 040 Study Team. Chlamydia and gonorrhea in HIV-infected pregnant women and infant HIV transmission. Sex Transm Dis 2015; 42 554–65.
| Chlamydia and gonorrhea in HIV-infected pregnant women and infant HIV transmission.Crossref | GoogleScholarGoogle Scholar | 26372927PubMed |
[4] Klausner JD. The sound of silence: missing the opportunity to save lives at birth. Bull World Health Organ 2013; 91 158–158A.
| The sound of silence: missing the opportunity to save lives at birth.Crossref | GoogleScholarGoogle Scholar | 23476083PubMed |
[5] Johnson LF, Lewis DA. The effect of genital tract infections on HIV-1 shedding in the genital tract: a systematic review and meta-analysis. Sex Transm Dis 2008; 35 946–59.
| The effect of genital tract infections on HIV-1 shedding in the genital tract: a systematic review and meta-analysis.Crossref | GoogleScholarGoogle Scholar | 18685546PubMed |
[6] Jarvis GA, Chang TL. Modulation of HIV transmission by Neisseria gonorrhoeae: molecular and immunological aspects. Curr HIV Res 2012; 10 211–7.
| Modulation of HIV transmission by Neisseria gonorrhoeae: molecular and immunological aspects.Crossref | GoogleScholarGoogle Scholar | 22384840PubMed |
[7] Ghys PD, Fransen K, Diallo MO, Ettiègne-Traore V, Coulibaly IM, Yeboue KM, Kalish ML, Maurcie C, Whitaker JP, Greenberg AE, Laga M. The associations between cervicovaginal HIV shedding, sexually transmitted diseases and immunosuppression in female sex workers in Abidjan, Cote d’Ivoire. AIDS 1997; 11 F85–93.
| The associations between cervicovaginal HIV shedding, sexually transmitted diseases and immunosuppression in female sex workers in Abidjan, Cote d’Ivoire.Crossref | GoogleScholarGoogle Scholar | 9342059PubMed |
[8] Mitchell C, Balkus JE, McKernan-Mullin J, Cohn SE, Luque AE, Mwachari C, Cohen CR, Coombs R, Frenkel LM, Hitti J. Associations between genital tract infections, genital tract inflammation, and cervical cytobrush HIV-1 DNA in US versus Kenyan women. J Acquir Immune Defic Syndr 2013; 62 143–8.
| Associations between genital tract infections, genital tract inflammation, and cervical cytobrush HIV-1 DNA in US versus Kenyan women.Crossref | GoogleScholarGoogle Scholar | 23018377PubMed |
[9] Gitau RW, Graham SM, Masese LN, Overbaugh J, Chohan V, Peshu N, Richardson BA, Joako W, Ndinya-Achola JO, McClelland RS. Effect of acquisition and treatment of cervical infections on HIV-1 shedding in women on antiretroviral therapy. AIDS 2010; 24 2733–7.
| Effect of acquisition and treatment of cervical infections on HIV-1 shedding in women on antiretroviral therapy.Crossref | GoogleScholarGoogle Scholar | 20871388PubMed |
[10] Wang CC, Mcclelland RS, Reiner MT, Overbaugh JM, Emery SR, Mandaliya KN, Chohan B, Ndinya-Achola J, Bwayo J, Kreiss JK. The effect of treatment of vaginal infections on shedding of human immunodeficiency virus type 1. J Infect Dis 2001; 183 1017–22.
| The effect of treatment of vaginal infections on shedding of human immunodeficiency virus type 1.Crossref | GoogleScholarGoogle Scholar | 11237825PubMed |
[11] Stime KJ, Garrett N, Sookrajh Y, Dorward J, Dlamini N, Olowolagba A, Sharma M, Barnabas RV, Drain PK. Clinic flow for STI, HIV, and TB patients in an urban infectious disease clinic offering point-of-care testing services in Durban, South Africa. BMC Health Serv Res 2018; 18 363
| Clinic flow for STI, HIV, and TB patients in an urban infectious disease clinic offering point-of-care testing services in Durban, South Africa.Crossref | GoogleScholarGoogle Scholar | 29751798PubMed |
[12] Helova A, Akama E, Bukusi EA, Musoke P, Nalwa WZ, Odeny TA, Onon M, Spangler SA, Turan JM, Wanga I, Abuogi LL. Health facility challenges to the provision of Option B+ in western Kenya: a qualitative study. Health Policy Plan 2017; 32 283–91.
| 28207061PubMed |
[13] Drake AL, Unger JA, Ronen K, Matemo D, Perrier T, DeRenzi B, Richardson BA, Kinuthia J, John-Stewart G. Evaluation of mHealth strategies to optimize adherence and efficacy of Option B+ prevention of mother-to-child HIV transmission: rationale, design and methods of a 3-armed randomized controlled trial. Contemp Clin Trials 2017; 57 44–50.
| Evaluation of mHealth strategies to optimize adherence and efficacy of Option B+ prevention of mother-to-child HIV transmission: rationale, design and methods of a 3-armed randomized controlled trial.Crossref | GoogleScholarGoogle Scholar | 28315480PubMed |
[14] Musoke P, Gakumo CA, Abuogi LL, Akama E, Bukusi E, Helova A, Nalwa WZ, Onono M, Spangler SA, Wanga I, Turan JM. A text messaging intervention to support Option B+ in Kenya: a qualitative study. J Assoc Nurses AIDS Care 2018; 29 287–99.
| A text messaging intervention to support Option B+ in Kenya: a qualitative study.Crossref | GoogleScholarGoogle Scholar | 29029867PubMed |
[15] Mudau M, Peters RP, De Vos L, Olivier DHJ, Davey D, Mkwanazi ES, McIntyre JA, Klausner JD, Medina-Marino A. High prevalence of asymptomatic sexually transmitted infections among human immunodeficiency virus-infected pregnant women in a low-income South African community. Int J STD AIDS 2018; 29 324–33.
| 28799824PubMed |
[16] National Department of Health. The 2015 National Antenatal Sentinel HIV & Syphilis Survey. Pretoria: National Department of Health; 2015.
[17] Chikovore J, Hart G, Kumwenda M, Chipungu GA, Desmond N, Corbett L. Control, struggle, and emergent masculinities: a qualitative study of men’s care-seeking determinants for chronic cough and tuberculosis symptoms in Blantyre, Malawi. BMC Public Health 2014; 14 1053
| Control, struggle, and emergent masculinities: a qualitative study of men’s care-seeking determinants for chronic cough and tuberculosis symptoms in Blantyre, Malawi.Crossref | GoogleScholarGoogle Scholar | 25301572PubMed |
[18] Chikovore J, Gillespie N, McGrath N, Orne-Gliemann J, Zuma T. Men, masculinity, and engagement with treatment as prevention in KwaZulu-Natal, South Africa. AIDS Care 2016; 28 74–82.
| 27421054PubMed |
[19] Hugo JM, Stall RD, Rebe K, Egan JE, Jobson G, De Swardt G, Struthers H, McIntyre JA. Knowledge, attitudes and beliefs regarding post exposure prophylaxis among South African men who have sex with men. AIDS Behav 2016; 20 350–6.
| Knowledge, attitudes and beliefs regarding post exposure prophylaxis among South African men who have sex with men.Crossref | GoogleScholarGoogle Scholar | 27539310PubMed |
[20] Peltzer K, Jones D, Weiss SM, Shikwane E. Promoting male involvement to improve PMTCT uptake and reduce antenatal HIV infection: a cluster randomized controlled trial protocol. BMC Public Health 2011; 11 778
| 21985332PubMed |
[21] Villar-Loubet OM, Bruscantini L, Shikwane ME, Weiss S, Peltzer K, Jones DL. HIV disclosure, sexual negotiation and male involvement in prevention-of-mother-to-child-transmission in South Africa. Cult Health Sex 2013; 15 253–68.
| HIV disclosure, sexual negotiation and male involvement in prevention-of-mother-to-child-transmission in South Africa.Crossref | GoogleScholarGoogle Scholar | 22974414PubMed |
[22] Ganle JK, Obeng B, Segbefia AY, Mwinyuri V, Yeboah JY, Baatiema L. How intra-familial decision-making affects women’s access to, and use of maternal healthcare services in Ghana: a qualitative study. BMC Pregnancy Childbirth 2015; 15 173
| How intra-familial decision-making affects women’s access to, and use of maternal healthcare services in Ghana: a qualitative study.Crossref | GoogleScholarGoogle Scholar | 26276165PubMed |
[23] Colombini M, James C, Ndwiga C, Team I, Mayhew SH. The risks of partner violence following HIV status disclosure, and health service responses: narratives of women attending reproductive health services in Kenya. J Int AIDS Soc 2016; 19 20766
| The risks of partner violence following HIV status disclosure, and health service responses: narratives of women attending reproductive health services in Kenya.Crossref | GoogleScholarGoogle Scholar | 27037140PubMed |
[24] Maman S, Van Rooyen H, Groves AK. HIV status disclosure to families for social support in South Africa (NIMH Project Accept/HPTN 043). AIDS Care 2014; 26 226–32.
| HIV status disclosure to families for social support in South Africa (NIMH Project Accept/HPTN 043).Crossref | GoogleScholarGoogle Scholar | 23875539PubMed |
[25] Bhatia DS, Harrison AD, Kubeka M, Milford C, Kaida A, Bajunirwe F, Wilson IB, Psaros C, Safren SA, Bangsberg DR, Smit JA, Matthews LT. The role of relationship dynamics and gender inequalities as barriers to HIV-serostatus disclosure: qualitative study among women and men living with HIV in Durban, South Africa. Front Public Heal 2017; 5 188
[26] Kalichman SC, DiMarco M, Austin J, Luke W, DiFonzo K. Stress, social support, and HIV-status disclosure to family and friends among HIV-positive men and women. J Behav Med 2003; 26 315–32.
| Stress, social support, and HIV-status disclosure to family and friends among HIV-positive men and women.Crossref | GoogleScholarGoogle Scholar | 12921006PubMed |
[27] Clum GA, Czaplicki L, Andrinopoulos K, Muessig K, Hamvas L, Ellen JM, and the Adolescent Medicine Trials Network for HIV/AIDS Interventions. Strategies and outcomes of HIV status disclosure in HIV-positive young women with abuse histories. AIDS Patient Care STDS 2013; 27 191–200.
| Strategies and outcomes of HIV status disclosure in HIV-positive young women with abuse histories.Crossref | GoogleScholarGoogle Scholar | 23596649PubMed |
[28] Zamudio-Haas S, Mudekunye-Mahaka I, Lambdin BH, Dunbar MS. If, when and how to tell: a qualitative study of HIV disclosure among young women in Zimbabwe. Reprod Health Matters 2012; 20 18–26.
| If, when and how to tell: a qualitative study of HIV disclosure among young women in Zimbabwe.Crossref | GoogleScholarGoogle Scholar | 23177677PubMed |
[29] Dunkle KL, Jewkes RK, Brown HC, Gray GE, McIntryre JA, Harlow SD. Gender-based violence, relationship power, and risk of HIV infection in women attending antenatal clinics in South Africa. Lancet 2004; 363 1415–21.
| Gender-based violence, relationship power, and risk of HIV infection in women attending antenatal clinics in South Africa.Crossref | GoogleScholarGoogle Scholar | 15121402PubMed |
[30] Jennings L, Na M, Cherewick M, Hindin M, Mullany B, Ahmed S. Women’s empowerment and male involvement in antenatal care: analyses of Demographic and Health Surveys (DHS) in selected African countries. BMC Pregnancy Childbirth 2014; 14 297
| Women’s empowerment and male involvement in antenatal care: analyses of Demographic and Health Surveys (DHS) in selected African countries.Crossref | GoogleScholarGoogle Scholar | 25174359PubMed |
[31] Morikawa E, Mudau M, Olivier D, De Vos L, Joseph Davey D, Price C, McIntyre JA, Peters RP, Klausner JD, Medina-Marino A. Acceptability and feasibility of integrating point-of-care diagnostic testing of sexually transmitted infections into a South African antenatal care program for HIV-infected pregnant women. Infect Dis Obstet Gynecol 2018; 2018 3946862
| Acceptability and feasibility of integrating point-of-care diagnostic testing of sexually transmitted infections into a South African antenatal care program for HIV-infected pregnant women.Crossref | GoogleScholarGoogle Scholar | 29861622PubMed |
[32] Creswell JW. Five qualitative approaches to inquiry. In Qualitative inquiry & research design: choosing among five approaches. Thousand Oaks: Sage; 2013. pp. 69–110.
[33] Atkinson S, Abu El Haj M. Domain analysis for qualitative public health data. Health Policy Plan 1996; 11 438–42.
| Domain analysis for qualitative public health data.Crossref | GoogleScholarGoogle Scholar | 10164200PubMed |
[34] Choko AT, Kumwenda MK, Johnson CC, Sakala DW, Chikalipo MC, Fielding K, Chikovore J, Desmond N, Corbett EL. Acceptability of woman-delivered HIV self-testing to the male partner, and additional interventions: a qualitative study of antenatal care participants in Malawi. J Int AIDS Soc 2017; 20 21610
| Acceptability of woman-delivered HIV self-testing to the male partner, and additional interventions: a qualitative study of antenatal care participants in Malawi.Crossref | GoogleScholarGoogle Scholar | 28691442PubMed |
[35] Walcott MM, Hatcher AM, Kwena Z, Turan JM. Facilitating HIV status disclosure for pregnant women and partners in rural Kenya: a qualitative study. BMC Public Health 2013; 13 1115
| Facilitating HIV status disclosure for pregnant women and partners in rural Kenya: a qualitative study.Crossref | GoogleScholarGoogle Scholar | 24294994PubMed |
[36] Fox AM, Jackson SS, Hansen NB, Gasa N, Crewe M, Sikkema KJ. In their own voices: a qualitative study of women’s risk for intimate partner violence and HIV in South Africa. Violence Against Women 2007; 13 583–602.
| In their own voices: a qualitative study of women’s risk for intimate partner violence and HIV in South Africa.Crossref | GoogleScholarGoogle Scholar | 17515407PubMed |
[37] Tong A, Sainsbury P, Craig J. Consolidated criteria for reporting qualitative research (COREQ): a 32-item checklist for interviews and focus groups. Int J Qual Health Care 2007; 19 349–57.
| 17872937PubMed |
[38] Daniels J, Maleke K, Lane T, Struthers H, McIntyre J, Kegeles S, Moore A, Coates T. Learning to live with HIV in the rural townships: a photovoice study of men who have sex with men living with HIV in Mpumalanga, South Africa. J Assoc Nurses AIDS Care 2017; 28 408–21.
| Learning to live with HIV in the rural townships: a photovoice study of men who have sex with men living with HIV in Mpumalanga, South Africa.Crossref | GoogleScholarGoogle Scholar | 28279587PubMed |
[39] McLean E, Renju J, Wamoyi J, Bukenya D, Ddaaki W, Church K, Zaba B, Wringe A. “I wanted to safeguard the baby”: a qualitative study to understand the experiences of Option B+ for pregnant women and the potential implications for “test-and-treat” in four sub-Saharan African settings. Sex Transm Infect 2017; 93 1–5.
[40] Townsend L, Jewkes R, Mathews C, Johnston LG, Flisher AJ, Zembe Y, Chopra M. HIV risk behaviours and their relationship to intimate partner violence (IPV) among men who have multiple female sexual partners in Cape Town, South Africa. AIDS Behav 2011; 15 132–41.
| HIV risk behaviours and their relationship to intimate partner violence (IPV) among men who have multiple female sexual partners in Cape Town, South Africa.Crossref | GoogleScholarGoogle Scholar | 20217470PubMed |
[41] Pines HA, Patterson TL, Rangel G, Martinez G, Bazzi AR, Ulibarri MD, Syvertsen JL, Martin NK, Strathdee SA. STI/HIV test result disclosure between female sex workers and their primary, non-commercial male partners in two Mexico-US border cities: a prospective study. Sex Transm Infect 2015; 91 207–13.
| STI/HIV test result disclosure between female sex workers and their primary, non-commercial male partners in two Mexico-US border cities: a prospective study.Crossref | GoogleScholarGoogle Scholar | 25298381PubMed |
[42] Petros G, Airhihenbuwa CO, Simbayi L, Ramlagan S, Brown B. HIV/AIDS “othering” in South Africa: the blame goes on. Cult Health Sex 2006; 8 67–77.
| HIV/AIDS “othering” in South Africa: the blame goes on.Crossref | GoogleScholarGoogle Scholar | 16500826PubMed |
[43] Maeri I, El Ayadi A, Getahun M, Charlebois E, Akatukwasa C, Tumwebaze D, Itiakorit H, Owino L, Kwarisiima D, Ssemmondo E, Sang N, Kabami J, Clark TD, Petersen M, Cohen CR, Bukusi EA, Kamya M, Havlir D, Camlin CS, and the Search Collaboration. “How can I tell?” Consequences of HIV status disclosure among couples in eastern African communities in the context of an ongoing HIV “test-and-treat” trial. AIDS Care 2016; 28 59–66.
| “How can I tell?” Consequences of HIV status disclosure among couples in eastern African communities in the context of an ongoing HIV “test-and-treat” trial.Crossref | GoogleScholarGoogle Scholar | 27421052PubMed |
[44] Daftary A, Padayatchi N.. Social constraints to TB/HIV healthcare: accounts from coinfected patients in South Africa. AIDS Care 2012; 24 1480–6.
| Social constraints to TB/HIV healthcare: accounts from coinfected patients in South Africa.Crossref | GoogleScholarGoogle Scholar | 22530855PubMed |
[45] Skovdal M, Campbell C, Madanhire C, Mupambireyi Z, Nyamukapa C, Gregson S. Masculinity as a barrier to men’s use of HIV services in Zimbabwe. Global Health 2011; 7 13
| 21575149PubMed |
[46] Nakayiwa S, Abang B, Packel L, Lifshay J, Purcell DW, King R, Ezati E, Mermin J, Coutinho A, Bunnell R. Desire for children and pregnancy risk behavior among HIV-infected men and women in Uganda. AIDS Behav 2006; 10 95–104.