Prevalence of human herpesvirus-8 among HIV-infected patients, intravenous drug users and the general population in Iran
Rezvan Kakavand-Ghalehnoei A , Zabihollah Shoja B , Alireza Najafi C , Mostafa Haji Mollahoseini D , Shohreh Shahmahmoodi A , Sayed Mahdi Marashi A , Ahmad Nejati A and Somayeh Jalilvand A E
+ Author Affiliations
- Author Affiliations
A Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran 14155, Iran.
B Department of Virology, Pasteur Institute of Iran, Tehran 1316943551, Iran.
C Department of Immunology, Faculty of Medicine, Iran University of Medical Sciences, Tehran 157856171, Iran.
D Department of Immunology, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran 1983963113, Iran.
E Corresponding author. Email: sjalilvand@sina.tums.ac.ir
Sexual Health 13(3) 295-298 https://doi.org/10.1071/SH15192
Submitted: 23 August 2015 Accepted: 30 December 2015 Published: 18 February 2016
Abstract
Studies looking at the frequency of human herpesvirus-8 (HHV-8) among Iranian blood donors have produced conflicting results. The aim of this study was to investigate the prevalence of HHV-8 DNA by using polymerase chain reaction methods among 168 healthy individuals, 60 intravenous drug users and 100 HIV-infected patients from Iran. The prevalence of HHV-8 was significantly higher among intravenous drug users (13.3%) compared with the general population (3.6%; P = 0.017). The HHV-8 genome was mostly detected among intravenous drug users who displayed high-risk sexual behaviours. Moreover, the HHV-8 genome was also detected in 8% of HIV-infected patients. The present study findings support the likelihood that the transmission of HHV-8 is via a sexual route in the Iranian population.
Additional keywords: sexual route, transmission.
References
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