Chlamydia prevention indicators for Australia: review of the evidence from New South Wales
Hammad Ali A E , Basil Donovan A B , Bette Liu A , Jane S. Hocking C , Paul Agius D , James Ward A , Christopher Bourne B , John M. Kaldor A and Rebecca J Guy AA The Kirby Institute, The University of New South Wales, Sydney, NSW 2052, Australia.
B Sydney Sexual Health Centre, Sydney Hospital, Sydney, NSW 2000, Australia.
C Centre for Women’s Health, Gender and Society, Melbourne School of Population Health, University of Melbourne, Melbourne, Vic. 2004, Australia.
D Mother and Child Health Research, La Trobe University, Melbourne, Vic., 3000, Australia.
E Corresponding author. Email: hali@kirby.unsw.edu.au
Sexual Health 9(5) 399-406 https://doi.org/10.1071/SH11183
Submitted: 19 December 2011 Accepted: 19 March 2012 Published: 20 August 2012
Abstract
Background: Annual notifications of chlamydia (Chlamydia trachomatis) diagnoses have increased steadily in Australia in the last decade. To guide public health programs, we developed 10 national chlamydia prevention indicators and report on each indicator for New South Wales (NSW). Methods: Using systematic methods, we reviewed the literature to report on the 10 health and behaviour indicators for 15- to 29–year-old heterosexuals in NSW from 2000. We included data with two or more time points. Results: Chlamydia notification rates (Indicator 1) in 15- to 29–year-olds have increased by 299%, from 237 per 100 000 population in 2001 to 946 per 100 000 population in 2010; and the percent of 15- to 34-year-olds with an annual Medicare-rebated chlamydia test (Indicator 2) increased by 326%, from 1.9% in 2001 to 8.1% in 2010. Since 2004, sentinel surveillance showed a 28% increase in chlamydia prevalence (Indicator 3) in 15- to 29-year-old females tested at their first sexual health service visit (from 8.5% in 2004 to 10.9% in 2010) but no significant increase in males. No NSW-specific chlamydia incidence (Indicator 4) was available. Pelvic inflammatory disease hospitalisation separations rate decreased from 0.58 per 1000 in 2001 to 0.44 per 1000 in 2010 in 15- to 29-year-old females (Indicator 5).Secondary school surveys in 2002 and 2008 showed chlamydia knowledge increased in males. The sexual risk-taking behaviour of young people remained unchanged (Indicators 6–10). Conclusions: Although notifications have risen steeply, the modest increase in chlamydia prevalence maybe a more realistic reflection of transmission rates. Strategies are needed to increase testing and to modify sexual risk behaviour. Crucial gaps in epidemiological data were identified.
Additional keywords: epidemiology, heterosexuals, surveillance, young people.
References
[1] Kong F, Guy RJ, Hocking JS, Merritt T, Pirotta M, Heal C, et al Australian general practitioner chlamydia testing rates among young people. Med J Aust 2011; 194 249–52.| 21381999PubMed |
[2] Department of Health and Ageing (DOHA). National notifiable diseases surveillance system. Canberra: DOHA; 2011. Available online at: http://www9.health.gov.au/cda/source/Rpt_5_sel.cfm [verified November 2011].
[3] NSW Department of Health. Chlamydia (genital only) notifications in NSW residents, 2012. Available online at: http://www.health.nsw.gov.au/data/diseases/chlamydia.asp [verified July 2012]
[4] Oakeshott P, Kerry S, Aghaizu A, Atherton H, Hay S, Taylor-Robinson D, et al Randomised controlled trial of screening for Chlamydia trachomatis to prevent pelvic inflammatory disease: the POPI (prevention of pelvic infection) trial. Brit Med J 2010; 340 c1642
| Randomised controlled trial of screening for Chlamydia trachomatis to prevent pelvic inflammatory disease: the POPI (prevention of pelvic infection) trial.Crossref | GoogleScholarGoogle Scholar | 20378636PubMed |
[5] Falk L, Coble B, Mjornberg P, Fredlund H. Sampling for Chlamydia trachomatis infection – a comparison of vaginal, first-catch urine, combined vaginal and first-catch urine and endocervical sampling. Int J STD AIDS 2010; 21 283–287.
| Sampling for Chlamydia trachomatis infection – a comparison of vaginal, first-catch urine, combined vaginal and first-catch urine and endocervical sampling.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BC3c3kvFWjsQ%3D%3D&md5=a638546575f44dc6c2a8b1735508df81CAS | 20378903PubMed |
[6] Michel C, Sonnex C, Carne C, White J, Magbanua J, Nadala E, et al Chlamydia trachomatis load at matched anatomic sites: implications for screening strategies. J Clin Microbiol 2007; 45 1395
| Chlamydia trachomatis load at matched anatomic sites: implications for screening strategies.Crossref | GoogleScholarGoogle Scholar | 17376879PubMed |
[7] Owusu-Edusei K, Bohm M, Chesson H, Kent C. Chlamydia screening and pelvic inflammatory disease: insights from exploratory time-series analyses. Am J Prev Med 2010; 38 652–7.
| Chlamydia screening and pelvic inflammatory disease: insights from exploratory time-series analyses.Crossref | GoogleScholarGoogle Scholar | 20494242PubMed |
[8] Idahl A, Lundin E, Elgh F, Jurstrand M, Møller J, Marklund I, et al Chlamydia trachomatis, Mycoplasma genitalium, Neisseria gonorrhoeae, human papillomavirus, and polyomavirus are not detectable in human tissue with epithelial ovarian cancer, borderline tumor, or benign conditions. Am J Obs Gyn 2010; 202 71
[9] Peterman T, Gottlieb S, Berman S. Chlamydia trachomatis screening: what are we trying to do? Int J Epidemiol 2009; 38 449
| Chlamydia trachomatis screening: what are we trying to do?Crossref | GoogleScholarGoogle Scholar | 19174542PubMed |
[10] Harryman L, Horner P. Chlamydia trachomatis and non-gonococcal urethritis. Medicine 2010; 38 249–54.
| Chlamydia trachomatis and non-gonococcal urethritis.Crossref | GoogleScholarGoogle Scholar |
[11] Trautmann G, Kip K, Richter H, Soper D, Peipert J, Nelson D, et al Do short-term markers of treatment efficacy predict long-term sequelae of pelvic inflammatory disease? Am J Obs & Gyn 2008; 198 30.
[12] Ness R, Soper D, Richter H, Randall H, Peipert J, Nelson D, et al Chlamydia antibodies, chlamydia heat shock protein, and adverse sequelae after pelvic inflammatory disease: the PID Evaluation and Clinical Health (PEACH) study. Sex Transm Dis 2008; 35 129
| Chlamydia antibodies, chlamydia heat shock protein, and adverse sequelae after pelvic inflammatory disease: the PID Evaluation and Clinical Health (PEACH) study.Crossref | GoogleScholarGoogle Scholar | 1:CAS:528:DC%2BD1cXptleitg%3D%3D&md5=86a3bea72f98e0513fa5c83dcf05bb8eCAS | 18300379PubMed |
[13] Gray-Swain M, Peipert J. Pelvic inflammatory disease in adolescents. Curr Opin Obs Gyn 2006; 18 503
| Pelvic inflammatory disease in adolescents.Crossref | GoogleScholarGoogle Scholar |
[14] Rutherford G, McFarland W, Spindler H, White K, Patel S, Aberle-Grasse J, et al Public health triangulation: approach and application to synthesizing data to understand national and local HIV epidemics. BMC Public Health 2010; 10 447
| Public health triangulation: approach and application to synthesizing data to understand national and local HIV epidemics.Crossref | GoogleScholarGoogle Scholar | 20670448PubMed |
[15] Joint United Nations Programme on HIV/AIDS. Implementation of the declaration of commitment on HIV/AIDS: core indicators. Geneva: United Nations General Assembly Special Session on HIV/AIDS; 2005.
[16] Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med 2009; 6 e1000097
| Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement.Crossref | GoogleScholarGoogle Scholar | 19621072PubMed |
[17] Dicker LW, Mosure DJ, Levine WC. Chlamydia positivity versus prevalence: what’s the difference? Sex Transm Dis 1998; 25 251
| Chlamydia positivity versus prevalence: what’s the difference?Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DyaK1c3kvVOhug%3D%3D&md5=40e7a3b60ed59b9c272e11f52e412d7bCAS | 9587176PubMed |
[18] LaMontagne D, Fenton K, Pimenta J, Catchpole M, Rogers P, Randall S, et al Using chlamydia positivity to estimate prevalence: evidence from the chlamydia screening pilot in England. Int J STD AIDS 2005; 16 323
| Using chlamydia positivity to estimate prevalence: evidence from the chlamydia screening pilot in England.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD2M3lvV2ktA%3D%3D&md5=1ae1810db40e9c3090afb7d9567451b2CAS | 15899088PubMed |
[19] Smith A, Agius P, Mitchell A, Barrett C, Pitts M. Secondary students and sexual health: Results of the 4th national survey of Australian secondary students, HIV/AIDS and sexual health. Melbourne: Australian Research Centre in Sex, Health & Society, La Trobe University; 2009. Available online at: http://www.latrobe.edu.au/arcshs/downloads/arcshs-research-publications/secondary-students-and-sexual-health-2008.pdf [verified December 2011].
[20] Kirby D. Emerging answers 2007: research findings on programs to reduce teen pregnancy and sexually transmitted diseases. Washington DC: National Campaign to Prevent Teen and Unplanned Pregnancy: 2007. Available online at: http://www.thenationalcampaign.org/EA2007/EA2007_full.pdf [verified December 2011].
[21] Royal Australian College of General Practitioners (RACGP). Guidelines for preventive activities in general practice,7th edition. Melbourne: RACGP; 2009.
[22] Sexual Health Society of Victoria. National management guidelines for sexually transmitted infection. 2008. Available online at: http://www.som.uq.edu.au/media/106223/sh7.pdf [verified July 2012]
[23] Guy R, Ali H, Liu B, Poznanski S, Ward J, Donovan B, et al Efficacy of interventions to increase the uptake of chlamydia testing in primary care: a systematic review. BMC Infect Dis 2011; 11 211
| Efficacy of interventions to increase the uptake of chlamydia testing in primary care: a systematic review.Crossref | GoogleScholarGoogle Scholar | 21816113PubMed |
[24] Pavlin NL, Gunn JM, Parker R, Fairley CK, Hocking J. Implementing chlamydia screening: what do women think? A systematic review of the literature. BMC Public Health 2006; 6 221
| Implementing chlamydia screening: what do women think? A systematic review of the literature.Crossref | GoogleScholarGoogle Scholar | 16948838PubMed |
[25] Grulich AE, Jin J. Sex in New South Wales: a companion report to The Australian and New Zealand Journal of Public Health 2003; Volume 27, Number 2. Sydney: National Centre in HIV Epidemiology and Clinical Research; 2003.
[26] Adam P, de Wit J, Hermans J, Story L, Edwards B, Murray C, et al. Understanding barriers to STI testing among young people: results from the online survey ‘Getting Down To it’. Sydney: National Centre in HIV Social Research, The University of New South Wales; 2011.
[27] Walker J, Fairley C, Bradshaw C, Tabrizi S, Chen M, Twin J, et al The difference in determinants of Chlamydia trachomatis and Mycoplasma genitalium in a sample of young Australian women. BMC Infect Dis 2011; 11 35
| The difference in determinants of Chlamydia trachomatis and Mycoplasma genitalium in a sample of young Australian women.Crossref | GoogleScholarGoogle Scholar | 21284887PubMed |
[28] Guy R, Kong F, Goller J, Franklin N, Bergeri I, Dimech W, et al A new national chlamydia sentinel surveillance system in Australia: evaluation of the first stage of implementation. Commun Dis Intell 2010; 34 319
[29] Vodstrcil L, Fairley C, Fehler G, Leslie D, Walker J, Bradshaw C, et al Trends in chlamydia and gonorrhea positivity among heterosexual men and men who have sex with men attending a large urban sexual health service in Australia, 2002–2009. BMC Infect Dis 2011; 11 158
| Trends in chlamydia and gonorrhea positivity among heterosexual men and men who have sex with men attending a large urban sexual health service in Australia, 2002–2009.Crossref | GoogleScholarGoogle Scholar | 21639943PubMed |
[30] O’Rourke KM, Fairley CK, Samaranayake A, Collignon P, Hocking JS. Trends in chlamydia positivity over time among women in Melbourne Australia, 2003 to 2007. Sex Transm Dis 2009; 36 763
| Trends in chlamydia positivity over time among women in Melbourne Australia, 2003 to 2007.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD1MjotVegtw%3D%3D&md5=537050bfdddb085fe062efa3bb8e7395CAS | 19801964PubMed |
[31] Guy R, Wand H, Franklin N, Fairley CK, Chen MY, O’Connor CC, et al Re-testing for chlamydia at sexual health services in Australia, 2004–08. Sex Health 2011; 8 242
| Re-testing for chlamydia at sexual health services in Australia, 2004–08.Crossref | GoogleScholarGoogle Scholar | 21592440PubMed |
[32] Hocking J, Temple-Smith M, Poznanski S, Vaisey V, Walker J, Guy R, et al. High chlamydia prevalence among young Australian men and women: results from the Australian Chlamydia Control Effectiveness Pilot. Australian Sexual Health Conference 2011. Canberra, Australia.
[33] Chen M, Fairley C, Donovan B. Discordance between trends in chlamydia notifications and hospital admission rates for chlamydia related diseases in New South Wales, Australia. Sex Transm Infect 2005; 81 318
| Discordance between trends in chlamydia notifications and hospital admission rates for chlamydia related diseases in New South Wales, Australia.Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD2MvhtFCkuw%3D%3D&md5=6b3e3a076abb2ff3e60eb1e4a88096b3CAS | 16061539PubMed |
[34] Cassell J, Low N. How can chlamydia diagnoses increase when their complications are declining? Sex Transm Infect 2005; 81 285
| How can chlamydia diagnoses increase when their complications are declining?Crossref | GoogleScholarGoogle Scholar | 1:STN:280:DC%2BD2MvhtFCksA%3D%3D&md5=dc4518e08c3dca9e2a1d3605e29470d8CAS | 16061531PubMed |
[35] Department of Health and Ageing (DOHA). Third national Aboriginal and Torres Strait Islander blood borne viruses and sexually transmissible infections strategy 2010–2013. Canberra: DOHA; 2010.
[36] Medicare Australia. Medicare benefits schedule (MBS) statistics, 2011. Medicare Australia; 2011. Available online at: https://www.medicareaustralia.gov.au/statistics/mbs_item.shtml [verified December 2011].
[37] Australian Bureau of Statistics (ABS). Statistics 2009. Canberra: ABS; 2009. Available online at: http://www.abs.gov.au/ausstats/abs@.nsf/web+pages/statistics [verified December 2011].
[38] NSW Ministry of Health. Separation statistics by principal diagnosis in ICD-10-AM, NSW, 2000 to 2010.