Herpes and HIV infection—has the time come to act?
Darren B. Russell
+ Author Affiliations
- Author Affiliations
Cairns Sexual Health Centre, PO Box 902, Cairns, QLD 4870, Australia. Email: darren_russell@health.qld.gov.au
Sexual Health 3(2) 67-71 https://doi.org/10.1071/SH04001
Submitted: 5 January 2004 Accepted: 16 January 2006 Published: 26 May 2006
Abstract
It has been known for some years that the ulcerative and inflammatory STIs lead to an increased risk of HIV transmission. In particular, there is a two- to four-fold increased risk of HIV-1 acquisition associated with prevalent herpes simplex virus type 2. The challenges are discussed herein.
References
[1]
[2]
[3]
[4] Fenton AF, Imrie J. Increasing rates of sexually transmitted diseases in homosexual men in Western Europe and the United States: why? Infect Dis Clin North Am 2005; 19 311–31.
| Crossref | GoogleScholarGoogle Scholar | PubMed | [verified April 2006].
[16] Fleming DT, McQuillan GM, Johnson RE, Nahmias AJ, Aral SO, Lee FK, et al. Herpes simplex virus type 2 in the United States, 1976 to 1994. N Engl J Med 1997; 337 1105–11.
| Crossref | GoogleScholarGoogle Scholar | PubMed | [verified April 2006].
[28] Dhawan D, Mayer KH. Microbicides to prevent HIV transmission: overcoming obstacles to chemical barrier protection. J Infect Dis 2006; 193(1): 36–44.
| Crossref | GoogleScholarGoogle Scholar | PubMed |
[29] Diamond C, Richardson JL, Milam J, Stoyanoff S, McCutchan JA, Kemper C, et al. Use of and adherence to antiretroviral therapy is associated with decreased sexual risk behavior in HIV clinic patients. J Acquir Immune Defic Syndr 2005; 39(2): 211–8.
| PubMed |
[30] Bateganya M, Colfax G, Shafer LA, Kityo C, Mugyenyi P, Serwadda D, et al. Antiretroviral therapy and sexual behavior: a comparative study between antiretroviral- naive and -experienced patients at an urban HIV/AIDS care and research center in Kampala, Uganda. AIDS Patient Care STDS 2005; 19(11): 760–8.
| Crossref | GoogleScholarGoogle Scholar | PubMed |
[31] Bunnell R, Ekwaru JP, Solberg P, Wamai N, Bikaako-Kajura W, Were W, et al. Changes in sexual behavior and risk of HIV transmission after antiretroviral therapy and prevention interventions in rural Uganda. AIDS 2006; 20(1): 85–92.
| Crossref | GoogleScholarGoogle Scholar | PubMed |
[32] Smith RJ, Bodine EN, Wilson DP, Blower SM. Evaluating the potential impact of vaginal microbicides to reduce the risk of acquiring HIV in female sex workers. AIDS 2005; 19(4): 413–21.
| Crossref | GoogleScholarGoogle Scholar | PubMed |
[33]