What does the future hold? Improved detection, treatment and management of One Health AMR
Trevor J. Lithgow
A and Mark A. T. Blaskovich B *
A
B
Prof. Trevor Lithgow is a biologist who studies drug-resistant bacteria at both the single cell and population level. He led the NHMRC Program in Cellular Microbiology that used the fundamental knowledge of bacterial cell biology to better understand mechanisms of AMR and the mechanics driving entry of bacteriophage (phage) into bacteria. Professor Lithgow was an ARC Federation Fellow, was an ARC Australian Laureate Fellow and is a Fellow of the Australian Academy of Science. In 2020, he established the inter-faculty Centre to Impact AMR located at Monash University. |
Prof. Mark Blaskovich is an ‘antibiotic hunter’ and Director of Translation for the Institute for Molecular Bioscience at The University of Queensland, as well as Director of the ARC Industrial Transformation Training Centre, CEAStAR, and the antibiotic crowdsourcing initiative CO-ADD. A medicinal chemist with 15 years of industrial drug development experience, since 2010 he has been developing new antibiotics, non-antibiotic therapies and diagnostics to detect and treat resistant bacterial and fungal infections, including multiple industry collaborations focused on AMR. |
Abstract
Antimicrobial resistance (AMR) is the poster child for the need for a ‘One Health’ approach that develops solutions across the human, agricultural and environmental sectors. This article provides a viewpoint of where AMR research is heading in the future, from the perspective of three Australian initiatives specifically established to combat AMR: the Centre to Impact AMR, the ARC Training Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance, and the Community for Open Antimicrobial Drug Discovery.
Keywords: antibiotic alternatives, antibiotics, antimicrobial resistance, One Health.
Prof. Trevor Lithgow is a biologist who studies drug-resistant bacteria at both the single cell and population level. He led the NHMRC Program in Cellular Microbiology that used the fundamental knowledge of bacterial cell biology to better understand mechanisms of AMR and the mechanics driving entry of bacteriophage (phage) into bacteria. Professor Lithgow was an ARC Federation Fellow, was an ARC Australian Laureate Fellow and is a Fellow of the Australian Academy of Science. In 2020, he established the inter-faculty Centre to Impact AMR located at Monash University. |
Prof. Mark Blaskovich is an ‘antibiotic hunter’ and Director of Translation for the Institute for Molecular Bioscience at The University of Queensland, as well as Director of the ARC Industrial Transformation Training Centre, CEAStAR, and the antibiotic crowdsourcing initiative CO-ADD. A medicinal chemist with 15 years of industrial drug development experience, since 2010 he has been developing new antibiotics, non-antibiotic therapies and diagnostics to detect and treat resistant bacterial and fungal infections, including multiple industry collaborations focused on AMR. |
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