A One Health genomic approach to antimicrobial resistance is essential for generating relevant data for a holistic assessment of the biggest threat to public health
Steven P Djordjevic A B and Branwen S Morgan A CA Australian Centre for Genomic Epidemiological Microbiology, Faculty of Science, University of Technology Sydney, Ultimo, NSW 2007, Australia
B Email: steven.djordjevic@uts.edu.au
C Email: Branwen.Morgan@uts.edu.au
Microbiology Australia 40(2) 73-76 https://doi.org/10.1071/MA19021
Published: 18 April 2019
Abstract
Antimicrobial resistance (AMR) threatens modern medicine as we know it. AMR infections may ultimately be untreatable and routine surgeries will become inherently risky1. By 2050 more people may die of drug-resistant infections (DRIs) every year than of cancer, which equates to more than 10 million annual deaths globally2 and the World Bank has estimated that AMR could cost the global economy $1 trillion every year after 2030. DRIs also lead to an increase in the length of hospital stays, the use of more toxic or costly antibiotics and an increased likelihood of death3. BRIC nations (Brazil, Russia, India, China) and socio-economically challenged countries and people who already have higher rates of infectious diseases will feel the greatest impact2. Indeed, AMR has been likened to the 2008 global financial crisis on an annual repeat cycle. That is because the effects of AMR are not just confined to the human medical sector. The veterinary sector is also reliant on the availability of antimicrobials to treat infectious diseases in companion and food-producing animals.
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