Commensal gut microbiota, genetic and epigenetic factors and susceptibility to inflammatory bowel disease
Stephen M Riordan
+ Author Affiliations
- Author Affiliations
Gastrointestinal and Liver Unit
Prince of Wales Hospital
Barker Street, Randwick
NSW 2031, Australia
Tel: +61 2 9382 3100
Fax: +61 2 9382 2727
Email: stephen.riordan@sesiahs.health.nsw.gov.au
Microbiology Australia 34(3) 151-152 https://doi.org/10.1071/MA13050
Published: 4 September 2013
Abstract
The incidence of inflammatory bowel disease, an often debilitating disorder, is increasing. Recent data indicate that complex interactions between the commensal gut microbiota, genetic and epigenetic factors and mucosal immunity are important in pathogenesis. Ongoing studies into these interactions will continue to advance understanding of processes responsible for the development of inflammatory bowel disease, as well as inform new and more effective approaches to management.
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