Streptomyces viewed from the inside: the application of proteomics to a model streptomycete

Abstract

Streptomyces coelicolor A3(2) has become the model system for this genus of antibiotic-producing bacteria, thanks to the life-time commitment of Sir David Hopwood to its genetic analysis. The determination of its complete genome sequence has made it an even more valuable model, opening up many analytical possibilities that emerge directly from the sequence, and also various functional genomics approaches.