Trichostrongylosis and wool growth. 2. The wool growth response of infected sheep to parenteral and duodenal cystine and cysteine supplementation

Abstract

Two experiments are reported. In experiment 1, light infections with the intestinal nematode Trichostrongylus colubriformis reduced wool growth of sheep by 42 per cent compared with pair-fed controls. There was no significant difference in wool growth between those sheep given a cystine supplement as an intraperitoneal pellet and those given a daily intra-duodenal injection of cystine, although cystine was poorly absorbed from the peritoneal cavity. In experiment 2, fifteen sheep were fed a maintenance ration and their wool growth rates defined. When six of the sheep were given a daily intra-duodenal drip containing 2 g cysteine hydrochloride, and six sheep were given the same drip intravenously, their wool growth rate increased by a mean of 33 per cent compared with the wool growth of the three untreated sheep, irrespective of the route of administration of the cysteine. Three sheep in each group of six were then lightly infected with Trichostrongylus colubriformis and the wool production of all sheep was measured in the presence and absence of the daily cysteine supplement via the two routes. The infection depressed wool growth, but did not influence the wool growth response to either route of cysteine supplementation. It was concluded that the reduced wool growth induced by trichostrongylosis could not be attributed to malabsorption of cysteine. Evidence was obtained that sheep resistant to Trichostrongylus colubriformis produced less wool when subjected to a larval challenge.